The invention discloses a traditional Chinese medicine for treating mucocutaneous lymph node syndromes. The traditional Chinese medicine is prepared from the following medicinal materials: raw gypsum, root of rehmannia, honeysuckle, fructus forsythiae, the root of kudzu vine, coptis chinensis, rattle stick dance, herba agrimoniae, salvia miltiorrhiza, herb of glabrous sarcandra, plumbago zeylanica, radix scrophulariae, radix ophiopogonis, lophatherum gracile, root of common peony, cortex moutan, ginseng, jasmine, the root of straight ladybell, Epipremum pinnatum, sarel spleenwort herb, dendrobium stem, herb of snow of june, dendrobe, radices trichosanthis, lalang grass rhizome, fermented soybean, polygala tenuifolia, hawthorn, peach kernel, scorpio, raw keel, raw oyster shell, bulbus fritillariae cirrhosae, immature bitter orange, rheum officinale, paris polyphylla, ranunculus sceleratus, folium isatidis, burdock, mint, rhizoma phragmitis, sweet wormwood, Ishige okamurae, rhizoma anemarrhenae, sheepear inula herb, trifolium lupinaster, euonymus porphyreus, urtica fissa pritz., oldenlandia diffusa, dandelion, chrysanthemum, cicada slough, ligusticum wallichii, red flower and radix curcumae. The clinical experiment proves that the traditional Chinese medicine disclosed by the invention can be used for safely and effectively treating the mucocutaneous lymph node syndromes.