The invention relates to a functional magnetic material for selective separation of pepsase, wherein the functional magnetic material is prepared by the following preparation steps: preparing ferroferric
oxide particles, namely preparing
silicon dioxide-coated ferroferric
oxide particles by using tetraethoxysilane as a
silicon source; adding functional monomers containing
glycosyl and positive charges into an
aqueous solution, freely polymerizing with allyl
triethoxysilane in the presence of an initiator, introducing
nitrogen into the
mixed solution to remove
oxygen, and carrying out a reaction at normal temperature; after the
polymerization is finished, adding ferroferric
oxide coated with
silicon dioxide, and carrying out a reaction in a water bath; and washing the obtained material withdistilled water, and
drying to obtain the material. The functional magnetic material disclosed by the invention is good in
biocompatibility and good in
dispersity; the material has the advantages ofuniform particle size, strong adsorption performance on pepsase, stable performance, realization of repeated use, repeated use for at least six times, realization of the separation of pepsase after the material is placed in a
room temperature dry environment for half a year, great saving of the use production cost, and wide application prospect.