The invention discloses an erasure method for a memory unit. The erasure method is characterized by comprising the steps of S1, receiving a programming operation instruction; S2, selecting a memory unit, connecting a word line and a bit line of the selected memory unit to a first programming voltage, suspending a word line of an unselected memory unit, and connecting a bit line of the unselected memory unit to a voltage source; S3, applying a programming pulse to the selected memory unit; S4, applying an erasure voltage pulse to a well CWELL of the selected memory unit; and S5, performing programming verification, and if the verification succeeds, then ending the programming operation, otherwise, performing the step S2. According to the erasure method for the memory unit, provided by an embodiment of the invention, the erasure pulse is applied to the well of the memory unit after the memory unit is programmed each time, so that electrons captured on a surface layer of the memory unit can be erased and the data retention property of the memory unit can be enhanced.