The invention discloses a high barrier PET/PP film, which is prepared by adding PP plastic particles and PET plastic particles into a co-extrusion casting film machine, and comprises a PET layer and a PP layer, wherein the PP plastic particles are prepared through blending modification, N,N'-(4,4'-methylenebiphenyl)bismaleimide, methylolpropane trimethyl acrylate, and 4,4'-dihydroxy diphenyl sulfide are added to improve the barrier property, the PET plastic particles are modified through a synthetic modification method, terephthalic acid and ethylene glycol are adopted as base materials, and 2-amino terephthalic acid, 2-nitro-terephthalic acid-4-methyl ester, 1,4-diacetoxybenzene, 1,4-benzenedimethanol, 2,2-dimethyl-1,3-propanediol, 2,3-dibromo-2-butene-1,4-diol, dimethyl 2-bromoterephthalate, 2,2-difluoro-1,3-benzodioxole, and magnesium fluorosilicate are added to adjust the performance. According to the present invention, the PET plastic particles and the PP plastic particles are extruded through the co-extrusion casting cast film machine to prepare the multi-layer casting film, wherein the effects of good high-barrier, fire retardation and bacterial resistance can be achieved through the complementation between the two materials.