The invention provides a zero-pesticide-residue Chinese wolfberry fruit production method which comprises the following steps: in the dormancy period of Chinese wolfberry fruits, cleaning a garden by using a sulfur-containing mineral pesticide; before and after the germination period, nicotine insecticides are adopted for prevention and treatment; in a new shoot growth period, an acaricide, a nicotine insecticide and a plant resistance inducer are combined for prevention and removal; in the mature period of new shoots, tetronic acid miticides and plant resistance inducers are combined for prevention and removal; in the initial flowering stage, neonicotinoid insecticides, acaricides and plant inducers are combined for prevention and removal; in the young fruit stage, pyrethroid insecticides, macrolide insecticides, acaricides and plant resistance inducers are combined for prevention and removal; a sulfur-containing bactericide and a plant resistance inducer are combined for prevention in the first crop fruit mature period; after the fruits are harvested, acaricides and fungicides are combined for prevention and treatment. According to the method, pesticide application is carried out in combination with the actual situation of diseases and insect pests in Chinese wolfberry cultivation, zero pesticide residue of Chinese wolfberry is achieved, the input of harmful chemicals is reduced, and the cultivation cost is reduced.