49 results about "Cyclooctanes" patented technology

The invention discloses a CHA type aluminum-silicon molecular sieve and a preparation method and application of an SCR catalyst, and belongs to the field of chemical synthesis technology and application thereof. The CHA type aluminosilicate zeolite molecular sieve is synthesized by adopting an N,N,N-trialkylbicyclo[2.2.2]octylammonium compound as an organic template agent, wherein the molar ratiorange of silicon dioxide to aluminum oxide in the product is 6-80, the average grain diameter is less than or equal to 500 nm, the total specific surface area is more than or equal to 400m2/g, the total pore volume is more than or equal to 0.20 ml/g, the micropore volume is not less than 0.10 ml/g, and the grain diameter in the crystal face (-210) direction of the molecular sieve is 50-160 nm. After hydrothermal treatment of the molecular sieve at 600-800 DEG C, the tetra-coordinated aluminum accounts for more than or equal to 90% of the total aluminum amount, and the hexa-coordinated aluminumaccounts for less than or equal to 10% of the total aluminum amount. The molecular sieve provided by the invention has high hydrothermal stability without large crystal grains, shows high nitrogen oxide reduction characteristics, and especially shows a catalyst with high nitrogen oxide reduction characteristics in a temperature range of 200-550 DEG C.

This invention relates to a new method for the stereospecific thiocarboxylation of organic compounds for the preparation of compounds according to formula (I):

wherein a compound of formula (II):

is reacted with a compound of formula (IIIa) or (IIIb):

then treating the obtained product with a thiocarboxylic acid or a salt thereof, and subsequently carrying out a nitration reaction.

A liquid fuel composition includes: a liquid fuel; and a sublimatable organic compound that has a sublimation point lower than 45° C. at atmospheric pressure, and that includes a skeleton selected from bicycloheptane, indane, pyrone, cyclopropane, cyclobutane, cyclopentane, cyclohexane, cycloheptane, cyclooctane, and benzene.

The invention discloses an ultrathin wearing layer normal-temperature asphalt modifier and a preparation method thereof. The ultrathin wearing layer normal-temperature asphalt modifier is prepared from the following raw materials in parts by mass: 55-65 parts of cyclooctane, 30-35 parts of modified epoxy resin glue, 0.6-1 part of a dispersant and 5-10 parts of a coupling agent. The preparation method comprises the following steps: putting the cyclooctane, the modified epoxy resin glue and the dispersant into a stirring kettle according to a ratio, heating to 100+/-5 DEG C, mixing, and uniformly stirring for 4-6 hours; further putting a coupling agent into the materials in the stirring kettle, and continuously stirring for 4-6 hours, thereby obtaining the product. By adopting the modifier,the rotary viscosity of asphalt at 60 DEG C can be reduced to 2.2-3.0Pa*s, and a mixed asphalt material can be spread for 1.0-2.0cm by using a common spreading machine within 50-60 DEG C; the construction temperature can be greatly reduced when being compared with a conventional construction temperature, and both the construction cost is reduced and the construction quality is ensured.

The invention belongs to the technical field of organic synthesis, and relates to a preparation method of a novel dihydropyrone coumarin compound. The preparation method comprises the following steps:in tetrahydrofuran, takingtriphenyl phosphine as a ligand and1,4-diazabicyclo[2.2.2] octane as an alkali, and under the catalytic action of Pd(OAc)2, reacting a dihydropyrone compound with a 3-cyano-4-methyl coumarin compound to prepare the 3-cyano-4-(6-dihydropyrone) methyl coumarin. The preparation method is mild in reaction condition, and the product yield is not lower than 52%. The inventionprovides a preparation method for obtaining dihydropyrone coumarin with excellent regioselectivity and high stereoselectivity by a simple and effective method. The preparation method is mild in reaction condition, green, high in reaction efficiency and more suitable for large-scale production requirements, and the prepared dihydropyrone coumarin compound is a compound with potential physiologicalactivity.

The invention discloses a bicyclo[3,3,0]octane polymerizable compound. The general structural formula of the bicyclo[3,3,0]octane polymerizable compound is as shown in a formula I which is described in the specification. The compound as shown in the formula I has the advantages of good intersolubility with other monomers, good ultraviolet ray endurance capability, etc. As an RM, the bicyclo[3,3,0]octane polymerizable compound has the advantages of good intersolubility, a high voltage holding rate (VHR), high polymerization activity (few monomer residuals), etc., and is especially applicable as the RM to liquid crystal mixtures of a PSA (polymer-supported alignment) mode and a PS (polymer stabilization) mode. Meanwhile, the compound can be applied to a liquid crystal display including a polymer-stabilized blue phase and has good dissolvability and polymerisability; and a final product has no or tiny retardation effect.

The invention relates to a method for removing methanol, n-butanol and isobutanol from wastewater of an amino resin workshop. The method comprises the steps of adding 1,3,3-trimethyl-2-oxa bicyclo[2.2.2]octane, flavanone glycoside, S(-)-2-amino-6-n-propyl amino-4,5,6,7-tetrahydro benzothiazole di-hydrochloride, 4-octyl phenol ethoxylate, 3',4'-dihydroxy-2-(methyl amino)acetophenone hydrochloride, 4-acetyloxy-3-methoxy-(2-propenyl)benzene, acet-4-methoxy-benzyl ester, 6,6,10-trimethyl bicyclo-3,1,1-heptyl-2-alkene, 2-[[1-(3-acetylthio-2-methyl propionyl)pyrrolidine-2-formyl]amino]-3- phenylpropionic acid and the like. The method has the advantages that complex capabilities to target objects are high; the deposition velocities of complex compounds are fast; the removal rate can reach 99.9 percent; the dose is low; hazard to a water body is avoided.

A dibenzocyclooctalkyl carboxylate compound with herbiciding activity and its composition can be used to effectively control the mono-and di-cotyledonous weeds.

A method for preparing (2S,3S)-3-amino-bicyclo[2.2.2]octane-2-carboxylate is in the field of pharmaceutical intermediate synthesis. The method uses 3-carbonyl-bicyclo[2.2.2]octane-2-carboxylate as the starting material and performs reductive amination, alkalinity configuration flip, and hydrogenation to remove the protecting group in sequence to obtain the target product. This synthesis method of (2S,3S)-3-amino-bicyclo[2.2.2]octane-2-carboxylate is characterized by a novel route, mild reaction conditions and low cost, with a yield of more than 65%.

The invention relates to a preparation method of an SGLTs inhibitor and a key intermediate of the SGLTs inhibitor. The SGLTs inhibitor is (1S, 2S, 3S, 4R, 5S)-5-(3-((2, 3-dihydrobenzo [b] [1, 4] dioxin-6-yl)methyl)-4-ethyl phenyl)-1-(hydroxymethyl)-6, 8-dioxabicyclo [3.2.1] octane-2, 3, 4-triol. According to the preparation method, 6-(2-ethyl-5-iodobenzyl)-2, 3-dihydrobenzo [b] [1, 4] dioxin is taken as a raw material, silyl is taken as a protecting group, and six-step reaction is carried out to prepare the product. The preparation method disclosed by the invention is simple to operate, high in yield of each step and stable in process, can adapt to industrial production requirements, solves the problem of drug accessibility, and is beneficial to acceleration of clinical development of the SGLTs inhibitor and drug marketing.

The invention relates to a preparation method for tert-butyl dioxy-3,8-diazabicyclo[3.2.1]octane-8-carboxylic acid, and mainly solves the technical problems that in an existing synthetic process, the yield is low, the reaction is not easy to control, the experimental operation is inconvenient and the like. By taking t-butyloxycarboryl methyl pyroglutamate as an initial raw material, the tert-butyl dioxy-3,8-diazabicyclo[3.2.1]octane-8-carboxylic acid is prepared by five-step reactions. The tert-butyl dioxy-3,8-diazabicyclo[3.2.1]octane-8-carboxylic acid obtained by the method provided by the invention is a useful intermediate or an intermediate product for synthesis of multiple drugs.

The present invention relates to a pharmaceutical composition and a lyophilisate of a diazabicyclooctane derivative represented by Compound I, a process for producing the same and methods for using the same.