316 results about "Ionized radiation" patented technology

In the case of forming a fine resist pattern, it is desired to further reduce the roughness of the resist pattern.SOLUTION: A substrate processing apparatus comprising: a heat treatment unit configured to bake a resist film; an exposure unit configured to irradiate the resist film having a portion irradiated with a first radioactive ray with a second radioactive ray; a development unit configured to form a resist pattern by development for removing a part of the resist film; and a control unit configured to control the exposure unit such that the second radioactive ray is collectively irradiated to an entire region of the resist film including the portion irradiated with the first radioactive ray and a portion other than the portion irradiated with the first radioactive ray. The first radiation is ionizing radiation or non-ionizing radiation, and the second radiation is non-ionizing radiation. When the first radiation is non-ionizing radiation, the second radiation is non-ionizing radiation having a wavelength longer than the wavelength of the first radiation. The resist film includes a metal oxide photoresist material.SELECTED DRAWING: Figure 1

The invention relates to the technical field of ionization radiation detection, in particular to an ionization chamber detection device, a measurement system and a use method. An ionization chamber detection device comprises: a housing having an accommodation space in which a mixed reaction gas is accommodated; the at least one separating polar plate is arranged in the accommodating space, and the separating polar plate is used for separating the accommodating space into at least two sections of detection cavities; the at least two signal collecting polar plates are respectively arranged in different detection chambers; and the at least two signal transmission lines are respectively connected with different signal collecting polar plates, one end of each signal transmission line is connected with the signal collecting polar plate, and the other end of each signal transmission line extends out of the shell and is suitable for being connected with a data collecting and processing unit. The invention provides an ionization chamber detection device, a measurement system and a use method, and aims to solve the problem that a conventional ionization chamber is generally used for intensity and dose measurement of regional radiation and is not suitable for position sensitive detection of a space smaller than the sensitive volume of the ionization chamber.

A system includes a cylindrical phantom and a conical structure disposed in the phantom. The conical structure is shaped as a frustum and emits Cherenkov radiation when exposed to ionizing radiation. The system can be used for calibration of an MR-Linac system by exposing the system to ionizing radiation. The Cherenkov radiation can be imaged during exposure to ionizing radiation.

The invention provides an anti-ionizing radiation fiber with high filling amount, high strength and high elasticity and a preparation method and application thereof, and belongs to the field of functional fiber materials.The preparation method comprises the steps that rare earth nitrate and citric acid are dissolved in an acidic alcohol aqueous solution, heated and stirred, the pH value is adjusted, sol is obtained, the sol is subjected to secondary heating treatment to obtain gel, and the gel is dried to obtain the high-filling-amount high-strength high-elasticity anti-ionizing radiation fiber. Aging, drying, grinding and calcining the gel to obtain rare earth composite powder; wherein the rare earth nitrate is a mixture of gadolinium nitrate, dysprosium nitrate and cerium nitrate; adding polyurethane into a mixed solution of DMF and xylene, stirring, adding the rare earth composite powder, stirring, and defoaming to obtain a spinning solution; preparing nascent fibers from the spinning solution through wet spinning; and drawing, washing and drying to obtain the anti-ionizing radiation fiber. The anti-ionizing radiation fiber prepared by the invention has excellent shielding property, mechanical property and air permeability.

The present invention relates to intracellular copper zinc superoxide dismutase inhibitors for protecting a subject from damage caused by radiation outbreak. The invention also relates to kits comprising SOD1 inhibitors and radiosensitizers for cancer cells, to the in vitro use of SOD1 inhibitors for protecting non-cancer cells from ionizing radiation, and to methods, compositions and uses related thereto.

The invention discloses an aviation radiation dose global distribution real-time calculation system based on ground detection equipment, which belongs to the technical field of radiation detection and comprises a ground radiation detection module, a dose simulation module and a data correction module. The ground radiation detection module is used for continuously collecting ionizing radiation data of an atmospheric bottom layer in a calm state and a solar high-energy particle event so as to improve data precision and a signal-to-noise ratio under a weak dose, and the dose simulation module receives latitude and longitude, height and time parameters of an aviation flight path, and calculates a standard atmospheric model and a cosmic ray energy spectrum in combination with the standard atmospheric model and the cosmic ray energy spectrum. The data processing module is used for calculating theoretical dose rates and particle type distribution of different height levels based on a Monte Carlo method and outputting the theoretical dose rates and the particle type distribution, and the data correction module is used for dynamically correcting parameters and weights of simulation results by combining measured data based on a deep learning algorithm of deep learning, so that adaptive fusion of the simulation data and the measured data is realized; and the ground radiation detection module comprises a semiconductor radiation detector, a data acquisition and preprocessing unit, a remote control module and a network communication module. The system has the characteristics of high real-time performance and wide coverage range.

The invention discloses an application of a pyrrosia lingua aqueous extract in preparation of a medicine for preventing and treating radioactive intestinal injury. Radioactive intestinal injury is a common complication of ionizing radiation, and has main pathological characteristics of intestinal mucosal barrier destruction, excessive release of inflammatory factors, increase of oxidative stress level and hematopoiesis and immune function inhibition. At present, no effective and safe prevention and treatment medicine is available. It is found for the first time that the pyrrosia lingua aqueous extract can inhibit expression (IL-6, TNF-alpha and IL-1beta) of inflammatory factors of radiation-induced MODE-K cells and relieve the oxidative stress level (malondialdehyde (MDA) is reduced, and the content of superoxide dismutase (SOD) and glutathione (GSH) is increased). In animal experiments, the pyrrosia lingua aqueous extract can reduce the levels of TNF-alpha and IL-1beta inflammatory factors in serum of irradiated mice and improve oxidative stress disorders such as MDA increase, SOD and GSH decrease and the like; the reduction of leukocytes and lymphocytes is relieved; the length of intestinal villus is promoted and recovered; the proportion of Ki67 positive cells in a crypt region is increased, so that the regeneration capacity of intestinal epithelial cells is enhanced. The pyrrosia lingua aqueous extract disclosed by the invention provides an experimental basis and an application prospect for developing a novel medicine for preventing and treating the radioactive intestinal injury.

A kind of vacuum system for nanodose detector gas density precision control belongs to ionizing radiation nanodose measurement field.The present application includes vacuum pump group unit, vacuum degree detection unit, logic control unit.The present application is aimed at the requirement of nanodose detector to vacuum degree and gas concentration, and realizes that working air pressure is in 1Torr by the pump group in vacuum system and the cooperation of PLC logic control and data monitoring, and gas pressure control precision reaches 0.01Torr.The system can provide ionizing radiation gas and low vacuum environment for nanodose detector, ensure that nanodose detector measurement signal is accurate and stable.The ionization degree of nanodose detector depends on the vacuum degree in cavity, and the vacuum degree of cavity depends on the concentration of gas in sensitive volume.The present application has the advantages of high precision, high accuracy, high reliability and the like.Through the present application, the vacuum environment of nanodose detector can be constant and sensitive gas is single, which can support the accurate measurement of nanodose detector.

This application proposes methods for synthesizing aromatic compounds using ionizing radiation based on N₂O, and methods for synthesizing aromatic compounds using industrial waste gas. The method includes: placing benzene and a combined gas containing N₂O in a sealed container, and adjusting the volume of the combined gas to bring the benzene in the sealed container to its saturated vapor pressure; irradiating the sealed container with radiation to cause the benzene to react and yield the aromatic compounds, wherein the radiation includes X-rays, gamma rays, or electron beams, the energy range of which is 0.0110 MeV, and the absorbed dose rate is 0.1 Gy / min to 1000 kGy / min. This method can synthesize aromatic compounds such as phenol in one step using ionizing radiation based on N₂O without the use of a catalyst, achieving precise and high-value utilization of N₂O.

The utility model discloses a radiation simulation training platform, which belongs to the technical field of ionizing radiation simulation training equipment and comprises a radiation simulation training chamber, and the outer surface of the radiation simulation training chamber is a lead boron polyethylene shielding case shell. A through groove is formed in the front end of the lead boron polyethylene shielding case shell, a transparent rubber plate is embedded in the through groove, a control box is arranged on one side of the front end of the lead boron polyethylene shielding case shell, and a ventilation fan is embedded in the upper portion of the other side of the front end of the lead boron polyethylene shielding case shell. A timer is arranged above the control box body, an opening and closing door is installed on one side of the lead boron polyethylene shielding case shell, and a bearing plate is arranged on the surface, facing one side, of the lead boron polyethylene shielding case shell. According to the radiation simulation training platform, on one hand, much external ionizing radiation interference can be isolated, a multi-source radiation environment can be simulated, meanwhile, data such as operation videos and operation time in the practical operation process of radiation monitoring personnel can be obtained, and assessment personnel can be helped to more accurately judge the assessment result of simulation training.

Provided are methods and compositions for enhancing radiotherapy in various cancers by administering dopamine receptor (DRD2)‐binding phenylpiperazine derivatives such as brexpiprazole, cariprazine, pipamperone, and perospirone. In vitro studies show that combining these agents with ionizing radiation (e.g., 5 Gy) significantly reduces cancer cell survival, suppresses metastatic and stemness markers (e.g., CD44, MMP‑2, Snail, Nanog), and promotes apoptosis. Fractionated or single‐fraction radiation regimens can be paired with DRD2 antagonists to lower treatment‐resistant phenotypes, decrease the likelihood of recurrence, and potentially reduce necessary radiation dosages. The approach applies to breast, prostate, lung, pancreatic, and brain cancers, among others. Depending on tumor characteristics, additional chemotherapeutic or immunotherapeutic agents may further improve outcomes.

The application discloses a kind of rich defect perovskite coupling single-atom catalyst and its preparation method and application.The preparation method of the catalyst is that perovskite material doped with trace noble metal is dispersed in deionized water, after adding hydroxyl shielding agent, using ionizing radiation treatment, to introduce the defect that perovskite surface is uniformly distributed and promote the dissolution of trace noble metal (such as Pt, Pd or Au), form high dispersion single-atom catalytic active center.The solution after irradiation is dried and calcined, finally obtain rich defect perovskite coupling single-atom catalyst.The catalyst of the application has excellent catalytic activity and stability in the cooperative removal reaction of catalytic carbon smoke and NO x , especially suitable for automobile exhaust purification, industrial waste gas treatment and diesel engine exhaust emission treatment and other fields, with good application prospect.

The present disclosure relates to physically crosslinked closed cell continuous multilayer foam structures comprising at least one foamed polypropylene / polyethylene layer having a TPU overlay. A multilayer structure comprising at least one layer of a foam composition and at least one layer of a cover composition may be co-extruded, the co-extruded structure is irradiated with ionizing radiation, and the irradiated structure is continuously foamed.

Disclosed herein is a physically crosslinked, closed-cell, continuous multilayer foam structure comprising: a coextruded foam layer comprising at least one of polypropylene and polyethylene and a crosslinked, coextruded cover layer comprising at least one of polypropylene and polyethylene. The multilayer foam structure can be obtained by coextruding a multilayer structure comprising at least one foam composition layer and at least one cover composition layer, irradiating the coextruded structure with ionizing radiation, and continuously foaming the irradiated structure.

The invention relates to the technical field of radiation protection, in particular to personal protection equipment for radiation detection, which comprises a helmet body, a support ring, connecting cloth and a protection component, and the protection component comprises an assembly groove, two standby grooves, a filter element, a magnetic annular unit, a lifting pushing unit and a transverse pushing mechanism. The lifting pushing unit drives the filter element needing to be replaced to move downwards, the filter element is pushed into the magnetic attraction annular unit through the transverse pushing mechanism and driven to the outside of the assembling groove through the magnetic attraction annular unit to be cleaned, and meanwhile the unused filter element is pushed out of the standby groove to be used in a linkage mode. After the external filter element is cleaned, the filter element is put into the assembly groove again for use; therefore, the working efficiency of ionizing radiation monitoring is remarkably improved, meanwhile, radioactive cross contamination of working places or workers caused by the fact that the workers need to enter and exit a high-activity area, a low-activity area, a clean area and other related areas of a non-sealed radioactive substance working place when the filter element is replaced is avoided, and therefore the physical health and life safety of the radiation workers are ensured.

The present invention relates to the fields of biology and medicine, and discloses the use of thiolutin in preventing and / or treating radiation-induced lung injury. Thiolutin prevents and / or treats radiation-induced lung injury induced by localized ionizing radiation exposure, including improving survival rates, inhibiting early acute radiation pneumonitis, improving long-term lung function, and inhibiting the development of pulmonary fibrosis. Therefore, it can be used as a potential drug for preventing and / or treating radiation-induced lung injury.

The application discloses application of a cerium monatomic functional material in preparation of a tumor radiotherapy sensitizer. SA In the material, cerium is dispersed on a nitrogen-doped carbon carrier in a monatomic form and forms a stable coordination structure with N / O. The application determines the structure-activity relationship of the unique physical and chemical structure and multiple enzyme activities, verifies the radiotherapy sensitization effect and biological safety in and out of the body. The material has multiple enzyme activities such as simulating peroxidase and glutathione oxidase, can efficiently catalyze ROS and consume GSH, and enhances DNA damage and apoptosis induced by ionizing radiation. In vitro clone formation experiments show that the radiotherapy sensitization ratio reaches 1.38, which is better than that of CeO2 nano clusters (1.17). In vivo experiments on tumor-bearing mice prove that the material combined with radiotherapy can significantly inhibit tumor growth, prolong survival time, and has good biocompatibility. The application provides a new strategy of high efficiency and low toxicity for tumor radiotherapy sensitization, and has a good clinical application prospect.

A method for producing a polytetrafluoroethylene micropowder that enables a clean working environment as well as a polytetrafluoroethylene powder. A method for producing a polytetrafluoroethylene micropowder, the method including irradiating a polytetrafluoroethylene powder having an average particle size of 700 μm or greater with ionizing radiation to provide a polytetrafluoroethylene micropowder having an average particle size of 20 μm or smaller.

A smartphone application and method for generating radio frequencies is provided. The application utilizes smartphone hardware to generate radio frequency energy that mitigates the effect of lachrymator particles released during onion cutting. By emitting non-ionizing radiation, the application reduces the discomfort and tearing experienced from the lachrymator particles. The intensity and frequency of non-ionizing radiation is controllable through the smartphone interface.

To provide a decorative sheet having sufficient flaw resistance and hard to generate a crack at the time of bending.SOLUTION: The decorative sheet 1 includes a thermoplastic resin base material sheet 11, a picture pattern layer 12 formed on the thermoplastic resin base material sheet, a transparent thermoplastic resin layer 13 formed on the picture pattern layer, and a surface protective part 20 formed on the transparent thermoplastic resin layer. The surface protective part contains a base resin and a low gloss agent, and has a first protective layer 21 formed on the transparent thermoplastic resin layer and a second protective layer 22 formed on the first protective layer. The base resin of the second protective layer includes a curable resin containing at least one of a thermosetting resin and an ionizing radiation curable resin, and a mixed curing agent obtained by mixing a curing agent in which hexamethylene diisocyanate nurate type and xylylene diisocyanate are mixed and a curing agent having a longer side chain attached to a six-membered ring than the hexamethylene diisocyanate nurate type at a mass ratio of 1:1.SELECTED DRAWING: Figure 1

The present invention relates to nanoparticles of a metal chosen from among platinum, bismuth or a mixture thereof, which are functionalised at their surface by functionalised polyethylene glycol, comprising in particular at least one OH, COOH, NH2 or SH functional group, and to their method of preparation, which comprises of the following steps:a) Mixing a precursor of nanoparticles with a functionalised polyethylene glycol, in particular comprising at least one OH, COOH, NH2 or SH functional group, in water;b) Exposing the mixture to ionising radiation.

The utility model discloses an ionizing radiation monitor with a protective structure, and relates to the technical field of monitors. The monitoring instrument comprises a monitoring instrument body; the number of the protection shells is two, the two protection shells are symmetrically distributed and arranged on the two sides of the monitor body in a sleeving mode, and a fixing assembly is installed between the two protection shells and used for fixing the two protection shells to the monitor body; the number of the damping assemblies is multiple. Through the synergistic effect of the protection shell, the fixing assembly, the damping assembly and the rubber pad, all-around protection of the monitor body is achieved, the protection shell provides external hard protection, the damping assembly and the rubber pad provide buffering and damping, the safety and stability of the monitor when the monitor falls off accidentally or is impacted are ensured, and the monitor is safe and reliable. Therefore, the service life of the monitor is prolonged, and the reliability and practicability of the monitor in a severe environment are improved.

The application provides a core-shell heterogeneous gradient structure anti-ionizing radiation powder and a preparation method and application thereof, and belongs to the field of radiation protection. The preparation method of the core-shell heterogeneous gradient structure anti-ionizing radiation powder comprises the following steps: adding a high-atomic-number metal salt into deionized water, sequentially performing aging, washing, drying and primary calcination to obtain a core layer; adding the core layer and a low-atomic-number metal salt into deionized water, sequentially performing aging, washing, drying and primary calcination to obtain a preliminary wrapped powder in which a low-atomic-number metal wraps a high-atomic-number metal core layer; adding the preliminary wrapped powder and a rare earth salt into deionized water, sequentially performing aging, washing, drying, primary calcination, secondary calcination, airflow pulverization and air rotation blowing to obtain the core-shell heterogeneous gradient structure anti-ionizing radiation powder. Through the synergy of the core-shell heterogeneous structure, high-atomic-number and low-atomic-number oxides and multiple rare earth elements, the shielding performance of the material is significantly improved.

The present disclosure is directed to a method of treating glioblastoma in a subject in need thereof comprising administering to said subject an efficient amount of a radiopharmaceutical compound. The present disclosure is also directed to methods of treating glioblastoma in a subject in need thereof comprising administering to said subject an efficient amount of a radiopharmaceutical compound in combination with a step of irradiating the subject with an efficient dose of ionizing radiations, and optionally, with a therapeutically efficient amount of an alkylating agent, preferably temozolomide.

The present invention relates to the field of medical therapy of lesions detrimental to a body. The system is capable of treatment with a non-invasive, ionizing kV energy radiation source. Locally focused energy can be used to definitively treat, or as an adjuvant to enhance immune modulators, to eliminate tumors. Distributed external beam entry points produce a significant advantageous dose profile at depth as intersecting beams accumulate in a narrow focus to treat a selected volume. Targeted disease may have enhanced sensitivity to the radiation by taking up an ionizing-radiation, treatment-localizing agent. This increases the effectiveness of an energy dose in the lesion. The pattern of beam output is effectively directed towards a desired location and kV x-rays traveling towards undesired locations, such as healthy tissue, are quenched. Targeting a lesion within the body with volumetrically discrete energy dose deposition can beneficially impact harmful lesions. Aiming the beam at a pathologic target is done while moving an x-ray source mechanically around a patient to distribute surface dose. The purpose of the focused energy deposition is to destroy and disable pathologic physiology, such as malignant masses. More specifically this invention relates to a system, which optimizes delivery of ionizing kV beams to a lesion alone or one containing treatment-localizing agents in higher concentration than the surrounding normal tissues. Thereby an optimal delivery of ionizing radiation becomes more destructive to a mass of abnormal cells upon interaction with the targeted site.

The present invention relates to a radiation shield (1) for protecting an operator from ionizing radiation, the shield (1) comprising a front wall structure (2) made of one or more radiation-resistant materials and a side wall structure (3) made of one or more radiation-resistant materials, which are connected to each other at a vertical or substantially vertical corner edge (4), the shield (1) comprising a base (5) equipped with wheels (6) resting on the ground. Furthermore, according to the invention, the shield (1) is characterized in that the front wall structure (2) comprises a lower portion (21) and an upper portion (22) movable relative to each other, the upper portion (22) of the front wall structure (2) being mounted to pivot about a vertical or substantially vertical pivot (7) in the region of the corner edge (4).

The utility model discloses an anti-radiation lead sliding door which comprises a concrete wall body arranged at the top of a concrete ground, a hanging bar is fixedly installed at the top of the concrete wall body, a keel is installed at the bottom of the hanging bar, and the bottom of the keel is fixedly connected with a double-layer paper surface gypsum board through screws. A white antibacterial inorganic coating is laid at the bottom of the double-layer gypsum plaster board, a flame-retardant board base layer is installed on the right side of the concrete wall body, and a grain ice fire board is laid on the surface of the flame-retardant board base layer. The double-layer paper surface gypsum board, the white antibacterial inorganic coating, the first black wiredrawing stainless steel, the barium sulfate coating layer and the second black wiredrawing stainless steel are used in cooperation, the overall attractiveness of the ionizing radiation lead sliding door after installation can be improved, the whole installation is easy, construction of workers is facilitated, and through the arrangement of the sliding door limiter, the service life of the ionizing radiation lead sliding door is prolonged. Sliding of the ionizing radiation lead sliding door can be limited, so that the ionizing radiation lead sliding door slides according to a limited track.

The invention discloses application of ellagic acid in preparation of a medicine for preventing or treating ionizing radiation injury, and belongs to the technical field of biological medicine and radiation protection. Experiments prove that ellagic acid with an effective concentration can inhibit lipid peroxidation, enhance the activity of glutathione transferase and superoxide dismutase and promote the expression of antioxidant related genes such as sod-1, sod-2, gst-1 and gst-29 and immune related genes such as lys-1, irg-1, irg-2 and mul-1, so that the ellagic acid with an effective concentration can inhibit lipid peroxidation and improve the activity of glutathione transferase and superoxide dismutase. Therefore, oxidative damage, inflammatory response, reduced stress tolerance, accelerated aging and shortened service life caused by ionizing radiation exposure are relieved, and the compound can be applied to preparation of drugs for preventing or treating ionizing radiation damage and is suitable for nuclear accident emergency protection, space radiation protection of astronauts and adjuvant therapy of tumor radiotherapy patients. The invention provides a theoretical basis for developing an efficient and low-toxicity ionizing radiation protective agent based on ellagic acid, and has a wide application prospect.

The invention provides a strain capable of resisting radiation damage as well as a product and application thereof, and relates to the technical field of probiotics capable of resisting radiation damage. The probiotic strains are separated from healthy breast milk and comprise lactobacillus gasseri LG02, lactococcus lactis LL6 and bifidobacterium adolescentis BA18, and the three probiotic strains can improve the survival rate after ionizing radiation; the LG02 or LL6 strain relieves damage of ionizing radiation to tissue structures of the heart, the liver, the spleen, the lung, the kidney, the stomach, the small intestine, the colon and the femur, the physiological function of an organism is maintained, and recovery of the tissue structures is accelerated; the LG02 or LL6 strain accelerates the body repair after radiotherapy, reduces the side reactions of diarrhea, stomachache, constipation and cough, and reduces the incidence rate of hematochezia and radiation pneumonitis; the LG02 or LL6 strain increases or recovers the number of leukocytes, and improves the hematopoietic ability and immunity of the organism; the LG02 or LL6 strain has the effects of inhibiting harmful bacteria, improving the anti-infection and anti-inflammation capability of the body and improving the resistance; the LG02 or LL6 strain can improve the oxidation resistance of the body and enhance the aging resistance of the body.