520 results about "Ionized radiation" patented technology

The invention provides anti-ionizing radiation powder with a core-shell heterogeneous gradient structure and a preparation method and application of the anti-ionizing radiation powder, and belongs to the field of radiation protection.The preparation method of the anti-ionizing radiation powder with the core-shell heterogeneous gradient structure comprises the following steps that high-atomic-number metal salt is added into deionized water, aging, washing, drying and primary calcination are conducted in sequence, and the anti-ionizing radiation powder with the core-shell heterogeneous gradient structure is obtained; a core layer is obtained; the core layer and low-atomic-number metal salt are added into deionized water, aging, washing, drying and primary calcination are sequentially conducted, and preliminary wrapping powder with the high-atomic-number metal core layer wrapped by low-atomic-number metal is obtained; and adding the preliminarily wrapped powder and rare earth salt into deionized water, and sequentially performing aging, washing, drying, primary calcining, secondary calcining, airflow crushing and air rotation purging to obtain the anti-ionizing radiation powder with the core-shell heterogeneous gradient structure. Through cooperation of the core-shell heterostructure, the high-atomic-number oxide, the low-atomic-number oxide and the multi-element rare earth element, the shielding performance of the material is remarkably improved.

In the case of forming a fine resist pattern, it is desired to further reduce the roughness of the resist pattern.SOLUTION: A substrate processing apparatus comprising: a heat treatment unit configured to bake a resist film; an exposure unit configured to irradiate the resist film having a portion irradiated with a first radioactive ray with a second radioactive ray; a development unit configured to form a resist pattern by development for removing a part of the resist film; and a control unit configured to control the exposure unit such that the second radioactive ray is collectively irradiated to an entire region of the resist film including the portion irradiated with the first radioactive ray and a portion other than the portion irradiated with the first radioactive ray. The first radiation is ionizing radiation or non-ionizing radiation, and the second radiation is non-ionizing radiation. When the first radiation is non-ionizing radiation, the second radiation is non-ionizing radiation having a wavelength longer than the wavelength of the first radiation. The resist film includes a metal oxide photoresist material.SELECTED DRAWING: Figure 1

The invention relates to the field of air conditioning and purification, in particular to a low-radiation plasma air purification generator and a control system thereof.According to the low-radiation plasma air purification generator and the control system thereof, through the structural design that the intensity of a three-level gradient electric field is gradually enhanced in the gas flowing direction, and in combination with an extended contact path of an S-shaped purification air duct, the air purification efficiency is improved; the reaction time and action intensity of plasma and pollutants are effectively improved, operation information is collected in real time, quantitative analysis is carried out, and operation of the air purification generator is subjected to standardized control, so that operation of the air purification generator can be automatically adjusted; the operation effect of the air purification generator is improved, ionizing radiation and ozone generation are restrained, and the air purification generator is prevented from damaging surrounding electronic equipment and the body health of people.

The present invention relates to the nanoparticles (NP) of the invention, compositions thereof and their use as therapeutic agents, in particular in the field of oncology and / or as imaging agents. The NPs consist of first nanoparticles of at least one high-Z metal oxide material, to which smaller second nanoparticles are covalently bonded at the surface of the first nanoparticles. The second nanoparticles consist of a) at least one noble metal or at least one metal oxide, metal sulfide, metal selenide or metal sulfide / selenide as a Fenton or Fenton-like reaction catalyst. The NPs of the invention produce a surprising therapeutic effect when exposed to ionizing radiation such as X-rays, gamma-rays, protons, neutrons, radioisotopes and / or electron beams. Therefore, these NPs can be used as radiosensitizers in the field of oncology. These nanoparticles can also be used as contrast agents.

The invention relates to the technical field of ionization radiation detection, in particular to an ionization chamber detection device, a measurement system and a use method. An ionization chamber detection device comprises: a housing having an accommodation space in which a mixed reaction gas is accommodated; the at least one separating polar plate is arranged in the accommodating space, and the separating polar plate is used for separating the accommodating space into at least two sections of detection cavities; the at least two signal collecting polar plates are respectively arranged in different detection chambers; and the at least two signal transmission lines are respectively connected with different signal collecting polar plates, one end of each signal transmission line is connected with the signal collecting polar plate, and the other end of each signal transmission line extends out of the shell and is suitable for being connected with a data collecting and processing unit. The invention provides an ionization chamber detection device, a measurement system and a use method, and aims to solve the problem that a conventional ionization chamber is generally used for intensity and dose measurement of regional radiation and is not suitable for position sensitive detection of a space smaller than the sensitive volume of the ionization chamber.

A system includes a cylindrical phantom and a conical structure disposed in the phantom. The conical structure is shaped as a frustum and emits Cherenkov radiation when exposed to ionizing radiation. The system can be used for calibration of an MR-Linac system by exposing the system to ionizing radiation. The Cherenkov radiation can be imaged during exposure to ionizing radiation.

To provide an antireflection film that has both high antireflection properties and superior scratch resistance, and that is capable of acquiring high antifouling property without relying on fluorine-containing compounds, as well as a method for producing such an antireflection film.SOLUTION: An antireflection film 10 comprises: a base film 12; a hard coat layer 14 formed on a surface of the base film 12; and an optical functional layer 16 formed on a surface of the hard coat layer 14. The optical functional layer 16 is formed from a cured product of an ionizing radiation-curable composition that contains a polyfunctional (meth)acrylate compound having a reactive group, and an amino-modified organopolysiloxane, where at least a part of the polyfunctional (meth)acrylate compound and at least a part of the amino-modified organopolysiloxane form an addition reaction product, and that further contains alumina particles surface-treated with a silane coupling agent having a reactive group capable of forming a bond with the polyfunctional (meth)acrylate compound.SELECTED DRAWING: Figure 1

The invention relates to a rare earth ion doped enhanced ionizing radiation luminescence low-dimensional halide scintillator and a preparation method and application thereof, and belongs to the technical field of scintillating materials. Aiming at the problems that the radiuses of RE ions and low-dimensional halide A5B3 (ClxBryI1-x-y) 8 materials are poor in lattice adaptation degree, the melting points of the RE ions and the low-dimensional halide A5B3 (ClxBryI1-x-y) 8 materials are difficult to consider in the doping process, concentration segregation is easy to occur and large-size crystals are difficult to grow, the solid-solution ratio of halogen anions and the doping concentration of the rare earth ions are regulated and controlled, namely 0.25 < = x < = 0.875, 0 < = y < = 1, x + y < = 1 and 0 < m < 10 are controlled; meanwhile, a rotation descent method is adopted for crystal growth, the scintillator single crystal material A5B3 (ClxBryI1-x-y) 8: m at% RE with the advantages of high ionizing radiation luminous efficiency, high light output and the like is finally obtained, and the material can be applied to the fields of X-ray imaging, gamma-ray detection, particle detection and the like.

The invention provides an anti-ionizing radiation fiber with high filling amount, high strength and high elasticity and a preparation method and application thereof, and belongs to the field of functional fiber materials.The preparation method comprises the steps that rare earth nitrate and citric acid are dissolved in an acidic alcohol aqueous solution, heated and stirred, the pH value is adjusted, sol is obtained, the sol is subjected to secondary heating treatment to obtain gel, and the gel is dried to obtain the high-filling-amount high-strength high-elasticity anti-ionizing radiation fiber. Aging, drying, grinding and calcining the gel to obtain rare earth composite powder; wherein the rare earth nitrate is a mixture of gadolinium nitrate, dysprosium nitrate and cerium nitrate; adding polyurethane into a mixed solution of DMF and xylene, stirring, adding the rare earth composite powder, stirring, and defoaming to obtain a spinning solution; preparing nascent fibers from the spinning solution through wet spinning; and drawing, washing and drying to obtain the anti-ionizing radiation fiber. The anti-ionizing radiation fiber prepared by the invention has excellent shielding property, mechanical property and air permeability.

The invention provides a construction method of a radioactive esophageal injury organ-like model. The construction method comprises the following steps: performing X-ray ionizing radiation on esophageal organs; wherein the esophageal organ comprises a rat esophageal organ, a mouse esophageal organ or a human esophageal organ; the radiation dosage is 0.5 to 4 Gy, and the radiation dosage rate is 1.5 to 2 Gy / min. Experimental results show that along with increase of irradiation dose, connection around spheres of human esophageal organs, mouse esophageal organs and rat esophageal organs is loose, cell debris is increased, and the sizes are smaller than those of normal organs at the same time. The construction of the radioactive esophageal injury organ-like model is of great significance for deeply understanding the injury mechanism of ionizing radiation to the esophagus, searching for effective protection and treatment measures and promoting the development of personalized radiotherapy.

The present invention relates to intracellular copper zinc superoxide dismutase inhibitors for protecting a subject from damage caused by radiation outbreak. The invention also relates to kits comprising SOD1 inhibitors and radiosensitizers for cancer cells, to the in vitro use of SOD1 inhibitors for protecting non-cancer cells from ionizing radiation, and to methods, compositions and uses related thereto.

The invention discloses a vacuum system for precisely controlling the gas density of a nano-dose detector, and belongs to the field of ionizing radiation nano-dose measurement. The system comprises a vacuum pump set unit, a vacuum degree detection unit and a logic control unit. According to the requirements of the nano dose detector for the vacuum degree and the gas concentration, the working air pressure is within 1 Torr and the air pressure control precision reaches 0.01 Torr through cooperation of a pump set in a vacuum system and PLC logic control and data monitoring. The system can provide gas for generating ionizing radiation and a low-vacuum environment for the nano-dose detector, and ensures that a measurement signal of the nano-dose detector is accurate and stable. The ionization degree of the nano dose detector depends on the vacuum degree in the cavity, and the vacuum degree of the cavity depends on the concentration of gas in the sensitive volume. The method has the advantages of high precision, high accuracy, high reliability and the like. According to the invention, the vacuum environment of the nano-dose detector is constant, the sensitive gas is single, and the precise measurement of the nano-dose detector can be supported.

The invention discloses an aviation radiation dose global distribution real-time calculation system based on ground detection equipment, which belongs to the technical field of radiation detection and comprises a ground radiation detection module, a dose simulation module and a data correction module. The ground radiation detection module is used for continuously collecting ionizing radiation data of an atmospheric bottom layer in a calm state and a solar high-energy particle event so as to improve data precision and a signal-to-noise ratio under a weak dose, and the dose simulation module receives latitude and longitude, height and time parameters of an aviation flight path, and calculates a standard atmospheric model and a cosmic ray energy spectrum in combination with the standard atmospheric model and the cosmic ray energy spectrum. The data processing module is used for calculating theoretical dose rates and particle type distribution of different height levels based on a Monte Carlo method and outputting the theoretical dose rates and the particle type distribution, and the data correction module is used for dynamically correcting parameters and weights of simulation results by combining measured data based on a deep learning algorithm of deep learning, so that adaptive fusion of the simulation data and the measured data is realized; and the ground radiation detection module comprises a semiconductor radiation detector, a data acquisition and preprocessing unit, a remote control module and a network communication module. The system has the characteristics of high real-time performance and wide coverage range.

The invention relates to the field of quartz crystal component testing, in particular to a batch test implementation device for radiation resistance of SMD (Surface Mount Device) packaged crystal oscillators, which is used for solving the problems of incapability of batch detection and low test efficiency in the prior art. According to the invention, a plurality of SMD packaged crystal oscillators to be tested are installed on a power-on part, and an electric connection and output signal transmission path is provided for the SMD packaged crystal oscillators; the radiation-resistant protection part is arranged below the power-on part, covers the monitoring control part and is used for isolating ionizing radiation for the monitoring control part; the monitoring control part is arranged below the radiation-resistant protection part and is mounted in the fixed part in an embedded manner; the power-on part, the radiation-resistant protection part and the fixing part are detachably and fixedly connected. According to the invention, the efficient batch performance test of the SMD packaged crystal oscillator is realized.

The utility model relates to the technical field of ionizing radiation monitors, in particular to an ionizing radiation monitor which comprises a protective shell, the top surface of the protective shell is in sliding connection with two protective covers, and a monitor body is arranged in the protective shell; the movable assembly is arranged on one side of the protection shell and used for driving the two protection covers to move, when the monitor body is disassembled, a first adjusting block is rotated to drive a threaded rod to rotate, and when the threaded rod rotates, one rack can be driven to move; when one rack moves, the other rack is driven to move through cooperation of a gear, when the two racks move, the distance between the two L-shaped plates can be adjusted through the two sliding blocks, after one ends of the two L-shaped plates are separated from the two clamping grooves, limiting of the monitor body can be relieved, and at the moment, the protection shell can be separated from the monitor body; and therefore, the protective shell or the monitor body can be replaced conveniently, and the practicability of the device is enhanced.

The invention discloses a method and system for detecting environment low-dose ionizing radiation, and belongs to the technical field of radiation detection.The method comprises the steps that house indoor data and building material ionizing radiation parameters are obtained, and an indoor radon concentration change model and a gamma radiation air absorbed dose rate change model are constructed; introducing the measured indoor radon concentration, gamma radiation air absorbed dose rate and indoor building material ionizing radiation parameters into an indoor radon concentration change model and a gamma radiation air absorbed dose rate change model to evaluate the future ionizing radiation condition, and constructing an effective dose evaluation model; indoor radon gas concentration, gamma radiation air absorbed dose rate and resident habits are introduced into an effective dose evaluation model to evaluate the influence of ionizing radiation on residents, an effective dose early warning model is constructed, and the daily total effective dose of ionizing radiation is introduced into the effective dose early warning model to evaluate the safety of ionizing radiation. According to the invention, the influence of the effective dose of ionizing radiation on residents is comprehensively evaluated in combination with resident habits.

The invention provides a planetary exploration intense radiation environment progressive ionizing radiation shielding protection method, which comprises the following steps: according to a planetary exploration task, carrying out space radiation environment analysis, forming an ionization total dose depth curve table, and formulating space environment protection design requirements; arranging total dose resistance capability indexes of all single machines to form a single machine ionization radiation resistance capability statistical table; carrying out protection grade confirmation on the matching of each single machine and the space environment protection design requirement; forming an intense radiation environment progressive shielding protection single machine list; performing effect evaluation on the shielding protection strategy of the progressive ionizing radiation screen; and formulating a progressive ionizing radiation shielding protection implementation scheme, defining a single-machine protection level, a shielding protection strategy, platform layout and guarantee conditions, and forming an engineering implementation scheme. The invention provides an intense radiation environment protection method aiming at the ionizing radiation protection requirement of a planetary exploration task, and the method can be applied and implemented in engineering.

The present invention relates to the use of small molecule compounds that allosterically inhibit ALC1 (CHD1L), in particular two classes allosteric inhibitors of ALC1 (CHD1L), of Formula (I) and Formula (II), that show a potentiating, preferably additive effect in the treatment of proliferative disease when combined with several classes of cancer drugs, namely inhibitors of Topoisomerase I, Topoisomerase II, ATM, ATR, Wee1, BRD, and MEK, or when combined with mitomycin C, paclitaxel, with ionizing radiation, or with an antibody drug conjugate with a tumor specific antibody conjugated to a TOP1 inhibitor. Furthermore, the present invention relates to said inhibitors of ALC1 of Formula (II) that show a synergistic effect in the treatment of pancreatic cancer or fallopian tube cancer when combined with a PARP inhibitor (Poly(ADP-ribose)-Polymerase inhibitor (PARPi)). By being synergistic with the function of said cancer drugs, said ALC1 inhibitors, in particular those of Formula (I) and Formula (II), potentiate the cancer cell killing properties of the aforementioned cancer drugs, in particular enabling therapeutic approaches where any of the aforementioned inhibitors is already used as part of the standard of care.

The invention discloses an application of a pyrrosia lingua aqueous extract in preparation of a medicine for preventing and treating radioactive intestinal injury. Radioactive intestinal injury is a common complication of ionizing radiation, and has main pathological characteristics of intestinal mucosal barrier destruction, excessive release of inflammatory factors, increase of oxidative stress level and hematopoiesis and immune function inhibition. At present, no effective and safe prevention and treatment medicine is available. It is found for the first time that the pyrrosia lingua aqueous extract can inhibit expression (IL-6, TNF-alpha and IL-1beta) of inflammatory factors of radiation-induced MODE-K cells and relieve the oxidative stress level (malondialdehyde (MDA) is reduced, and the content of superoxide dismutase (SOD) and glutathione (GSH) is increased). In animal experiments, the pyrrosia lingua aqueous extract can reduce the levels of TNF-alpha and IL-1beta inflammatory factors in serum of irradiated mice and improve oxidative stress disorders such as MDA increase, SOD and GSH decrease and the like; the reduction of leukocytes and lymphocytes is relieved; the length of intestinal villus is promoted and recovered; the proportion of Ki67 positive cells in a crypt region is increased, so that the regeneration capacity of intestinal epithelial cells is enhanced. The pyrrosia lingua aqueous extract disclosed by the invention provides an experimental basis and an application prospect for developing a novel medicine for preventing and treating the radioactive intestinal injury.

A kind of vacuum system for nanodose detector gas density precision control belongs to ionizing radiation nanodose measurement field.The present application includes vacuum pump group unit, vacuum degree detection unit, logic control unit.The present application is aimed at the requirement of nanodose detector to vacuum degree and gas concentration, and realizes that working air pressure is in 1Torr by the pump group in vacuum system and the cooperation of PLC logic control and data monitoring, and gas pressure control precision reaches 0.01Torr.The system can provide ionizing radiation gas and low vacuum environment for nanodose detector, ensure that nanodose detector measurement signal is accurate and stable.The ionization degree of nanodose detector depends on the vacuum degree in cavity, and the vacuum degree of cavity depends on the concentration of gas in sensitive volume.The present application has the advantages of high precision, high accuracy, high reliability and the like.Through the present application, the vacuum environment of nanodose detector can be constant and sensitive gas is single, which can support the accurate measurement of nanodose detector.

This application proposes methods for synthesizing aromatic compounds using ionizing radiation based on N₂O, and methods for synthesizing aromatic compounds using industrial waste gas. The method includes: placing benzene and a combined gas containing N₂O in a sealed container, and adjusting the volume of the combined gas to bring the benzene in the sealed container to its saturated vapor pressure; irradiating the sealed container with radiation to cause the benzene to react and yield the aromatic compounds, wherein the radiation includes X-rays, gamma rays, or electron beams, the energy range of which is 0.0110 MeV, and the absorbed dose rate is 0.1 Gy / min to 1000 kGy / min. This method can synthesize aromatic compounds such as phenol in one step using ionizing radiation based on N₂O without the use of a catalyst, achieving precise and high-value utilization of N₂O.

The utility model discloses a radiation simulation training platform, which belongs to the technical field of ionizing radiation simulation training equipment and comprises a radiation simulation training chamber, and the outer surface of the radiation simulation training chamber is a lead boron polyethylene shielding case shell. A through groove is formed in the front end of the lead boron polyethylene shielding case shell, a transparent rubber plate is embedded in the through groove, a control box is arranged on one side of the front end of the lead boron polyethylene shielding case shell, and a ventilation fan is embedded in the upper portion of the other side of the front end of the lead boron polyethylene shielding case shell. A timer is arranged above the control box body, an opening and closing door is installed on one side of the lead boron polyethylene shielding case shell, and a bearing plate is arranged on the surface, facing one side, of the lead boron polyethylene shielding case shell. According to the radiation simulation training platform, on one hand, much external ionizing radiation interference can be isolated, a multi-source radiation environment can be simulated, meanwhile, data such as operation videos and operation time in the practical operation process of radiation monitoring personnel can be obtained, and assessment personnel can be helped to more accurately judge the assessment result of simulation training.

Provided are methods and compositions for enhancing radiotherapy in various cancers by administering dopamine receptor (DRD2)‐binding phenylpiperazine derivatives such as brexpiprazole, cariprazine, pipamperone, and perospirone. In vitro studies show that combining these agents with ionizing radiation (e.g., 5 Gy) significantly reduces cancer cell survival, suppresses metastatic and stemness markers (e.g., CD44, MMP‑2, Snail, Nanog), and promotes apoptosis. Fractionated or single‐fraction radiation regimens can be paired with DRD2 antagonists to lower treatment‐resistant phenotypes, decrease the likelihood of recurrence, and potentially reduce necessary radiation dosages. The approach applies to breast, prostate, lung, pancreatic, and brain cancers, among others. Depending on tumor characteristics, additional chemotherapeutic or immunotherapeutic agents may further improve outcomes.

A nuclear power generation system capable of generating power with robust shielding against ionizing radiation is provided. This nuclear power generation system includes: a nuclear reactor that includes a core fuel, and a reactor vessel that surrounds to cover the core fuel and to shield a space having the core fuel for shielding against ionizing radiation; a thermal conductor that is disposed inside of the reactor vessel, and transfers heat of the core fuel via solid thermal conduction; a refrigerant circuit that includes a pipe with a part inserted in the reactor vessel and another part disposed outside of the reactor vessel, and through which refrigerant is passed, and that circulates the refrigerant exchanging heat with the thermal conductor; a turbine that is rotated by the refrigerant circulating through the refrigerant circuit; and a generator that is rotated integrally with the turbine.

The invention relates to an adjustable load space test support method. The load cold table and the telescopic device fix the load, the pressure is regulated and controlled through the pressure control assembly, the temperature is regulated and controlled through the heat support assembly and the load cold table, and the environment with the adjustable short-time space exposure radiation quantity is provided for the test load by combining stretching and retracting of the telescopic device and opening and closing of the load cabin door. Comprising the step of providing a load test support method for pressure control and temperature regulation in the microgravity cabin. A vacuum exposure test method which is long in time consumption and high in risk and is transferred by grabbing a load adapter through a mechanical arm is improved, and a load space test supporting method with exposure ionizing radiation and adjustable temperature in a microgravity cabin is provided. According to the load space test supporting method, the telescopic device carrying the load directly extends out of the cabin to carry out an exposure test, and the telescopic device can retract into the spacecraft at any time to achieve urgent danger avoiding. According to the invention, diversification of load space test support methods is expanded, complexity and cost of test support are reduced, and test safety and efficiency are improved.

The invention relates to application of amlexanox and polydatin in preparation of a preparation for preventing and / or treating radiation-induced lung injury, and belongs to the technical field of medicines. The invention provides application of amlexanox combined with polydatin in preparation of a medicine for preventing and / or treating radiation-induced lung injury. The amlexanox and the polydatin are combined for use, so that the radiation-induced lung injury caused by ionizing radiation can be well prevented and / or treated, and the survival rate of a radiation-induced lung injury model mouse is increased by more than 50% on the premise of remarkably reducing the administration dosage of the amlexanox and the polydatin; the traditional Chinese medicine composition has the characteristics of small dosage, excellent prevention and / or treatment effect, no toxic or side effect and no dose dependence.

The application discloses a kind of rich defect perovskite coupling single-atom catalyst and its preparation method and application.The preparation method of the catalyst is that perovskite material doped with trace noble metal is dispersed in deionized water, after adding hydroxyl shielding agent, using ionizing radiation treatment, to introduce the defect that perovskite surface is uniformly distributed and promote the dissolution of trace noble metal (such as Pt, Pd or Au), form high dispersion single-atom catalytic active center.The solution after irradiation is dried and calcined, finally obtain rich defect perovskite coupling single-atom catalyst.The catalyst of the application has excellent catalytic activity and stability in the cooperative removal reaction of catalytic carbon smoke and NO x , especially suitable for automobile exhaust purification, industrial waste gas treatment and diesel engine exhaust emission treatment and other fields, with good application prospect.

Compositions and methods of improving radiation therapy are provided. The composition typically includes an effective amount of 7-DHC or a derivative or analog thereof. The methods typically include administering the composition to a subject in need thereof in combination with one or more doses of radiation therapy, preferably non-ultraviolet radiation therapy. A preferred radiation is ionizing radiation. The compositions and methods can be used to treat tumors, e.g., benign and malignant tumors. Thus, methods of treating cancer are provided. In preferred embodiments, the 7-DHC or a derivative or analog thereof is encapsulated or incorporated into nanoparticles. The particles can be, for example, polymeric nanoparticles, lipoprotein or lipoprotein-like particles, liposomes, inorganic nanoparticles, or a combination thereof. In some embodiments, the 7-DHC or analog thereof is derivatized with a polymer or saccharide, which is some embodiments, can self-assemble into particles. In some embodiments, the nanoparticles further include a targeting agent coupled thereto.

The invention relates to the field of biology and medicine, and discloses application of dapam nitrile in prevention and / or treatment of radioactive intestinal injury. The inventor of the invention finds that dapam nitrile can protect radioactive intestinal injury induced by ionizing radiation local irradiation, including improvement of tissue pathological injury, promotion of intestinal crypt cell regeneration, inhibition of intestinal cell apoptosis, improvement of intestinal cell pyroptosis and reduction of serum inflammatory factor level; therefore, the compound can be used as a potential medicine for preventing and / or treating radioactive intestinal injury.

The present disclosure relates to physically crosslinked closed cell continuous multilayer foam structures comprising at least one foamed polypropylene / polyethylene layer having a TPU overlay. A multilayer structure comprising at least one layer of a foam composition and at least one layer of a cover composition may be co-extruded, the co-extruded structure is irradiated with ionizing radiation, and the irradiated structure is continuously foamed.