6 results about "Melibiose" patented technology

The invention relates to the technical field of biological medicine, in particular to application of a pharmaceutical composition in preparation of a medicine for treating diabetic nephropathy, the pharmaceutical composition is composed of active ingredients and pharmaceutically acceptable auxiliary materials, and the pharmaceutical composition is characterized in that the active ingredients are selected from the group consisting of active ingredients and pharmaceutically acceptable auxiliary materials; the active component is selected from one or more of melibiose or pharmaceutically acceptable salt, isomer and precursor thereof. The melibiose disclosed by the invention has the advantages that the melibiose can obviously improve diabetic mouse glomerular endothelial cell injury, reduce proteinuria, improve inflammation and play a role in protecting kidneys.

Promoters inducible with sugars such as glucose, maltose, raffinose, sucrose, arabinose, galactose, lactose, melibiose, and ribose; recombinant nucleic acids comprising the sugar-inducible promoters, including sugar-excisable nucleic acid cassettes comprising the sugar-inducible promoters; recombinant microorganisms comprising the recombinant nucleic acids; and methods of using same.

The invention discloses a composition for treating the problem of skin decline, a preparation method and application, and belongs to the technical field of health care and skincare, and the composition is mainly prepared from the following raw materials: cactus flower extract, abalone peptide, melibiose and the like. After the cactus flower extract, the melibiose and the abalone peptide are combined, the postpartum anti-aging effect is achieved through a new mechanism, and the anti-aging effect is obviously improved and is superior to that of any single component. Experimental research proves that the composition has anti-aging activity by activating calreticulin of fibroblasts in postpartum skin, enhancing the antigen presentation capacity of dendritic cells, activating a non-classical NF-kappa B signal channel, promoting lymphocyte homing and prolonging T cell telomere, does not have the mechanism when any component is independently used, and has no toxic or side effect. The composition is innovative in the anti-aging aspect.

This invention provides a fecal microbial freeze-drying protective solution. Through the synergistic effect of components such as phosphorylcholine polymer, glycerol, trehalose, ergothioneine, L-cysteine, melibiose, isomaltooligosaccharide, and stachydrine, it effectively reduces the damage to bacterial activity during the freeze-drying process, improves the stability of freeze-drying preservation, and enhances the ability to maintain bacterial metabolic activity. It plays a significant role in maintaining the diversity and functional activity of the bacterial community.

The invention belongs to the technical field of enzyme engineering, and particularly relates to a method for enhancing alpha-galactosidase oligosaccharide synthesis capacity through site-specific mutagenesis and an engineered enzyme. The mutant enzyme K480R for enhancing the oligosaccharide synthesis capability of the alpha-galactosidase is obtained by carrying out site-directed mutagenesis on the alpha-galactosidase from lactobacillus amyloliquefaciens L6 by utilizing a site-directed mutagenesis technology, has efficient and accurate catalytic capability, can efficiently convert melibiose into oligosaccharide, has the conversion rate of 34.30%, and can be used for preparing a mutant enzyme K480R for enhancing the oligosaccharide synthesis capability of the alpha-galactosidase. The activity of the alpha-galactosidase is higher than that of alpha-galactosidase derived from bacteria reported in China, side reactions are greatly reduced, and the production efficiency is improved. The synthesized oligosaccharide provides a new effective component for developing novel functional foods and medical products in the food field and the medical health care aspect. Therefore, the mutant enzyme has application potential in multiple industries such as food, medicine, cosmetics and the like, industrial innovation can be promoted, and considerable economic and social benefits can be created.

A laundry composition is disclosed comprising a plurality of hollow particles, wherein the hollow particle comprises (a) from 20 to 95% by weight of a water-soluble carrier selected from a carbohydrate, an inorganic alkali metal salt, an organic alkali metal salt, an inorganic alkaline earth metal salt, an organic alkaline earth metal salt, a urea and mixtures thereof, and (b) from 0.1 to 30% by weight of benefit agents; and wherein the hollow particles have (i) a flat base and a longitudinal length perpendicular to the base; and (ii) a hollow channel extending throughout the particles along the longitudinal length direction; wherein the water-soluble carrier comprises sugar selected from dextrose, sucrose, fructose, glucose, isoglucose, rhamnose, fucose, deoxyribose, ribose, trehalose, xylose, mannose, arabinose, galactose, cellobiose, lactose, maltose, isomaltose, melibiose, gentobiose, maltotriose, raffinose, panose, and mixtures thereof; and wherein the benefit agent is perfume.