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White paeony root total glycoside nano preparation for treating inflammatory diseases and preparation method of white paeony root total glycoside nano preparation

The invention relates to the technical field of medical drug preparation, in particular to a total glucosides of paeony nano preparation for treating inflammatory diseases and a preparation method of the total glucosides of paeony nano preparation. The nanogel dispersoid is formed by self-assembling molecules in a water phase through thermal induction gelatinization and a subsequent cooling process; the mass ratio of the total glucosides of paeony to the starch is (1: 10)-(1: 50); the average hydrated particle size of gel particles in the nanogel dispersion ranges from 80 nanometers to 300 nanometers, and the polydispersity index of the gel particles is smaller than 0.3. According to the total glucosides of paeony nano preparation for treating inflammatory diseases and the preparation method thereof, the process is simple, the cost is low, complicated equipment or organic solvents are not needed, the preparation is very suitable for industrial production, edible starch is taken as a carrier material, the biocompatibility is excellent, the safety is high, the enrichment of medicines at inflammatory parts can be effectively improved, the action time can be prolonged, and the application prospect is wide. Therefore, curative effect is improved, and administration frequency is reduced.
Owner:UNIV OF SCI & TECH OF CHINA

A spore leaf of undaria pinnatifida-derived active peptide and a preparation method and application thereof

ActiveCN122011110BHas antioxidant propertiesBe activeSporelingUndaria pinnatifida
The application belongs to the technical field of biology, and discloses a Undaria pinnatifida sporophyll-derived active peptide as well as a preparation method and application thereof. The Undaria pinnatifida sporophyll-derived active peptide is selected from at least one of peptides with amino acid sequences as shown in SEQ. ID. NO. 1-4. The Undaria pinnatifida sporophyll-derived active peptide is obtained by screening from Undaria pinnatifida sporophyll through bioinformatics tools and molecular docking. Experiments prove that the Undaria pinnatifida sporophyll-derived active peptide has antioxidant and anti-inflammatory activities, and can be used for preparing antioxidant or antioxidant-assisted products and anti-inflammatory products.
Owner:LUDONG UNIVERSITY +1