46results about How to "Lower glucose levels" patented technology

The invention relates to a process for preparing mannitol by using glucose as raw material, which comprises the steps of, converting glucose solution partly into mannose under acidic condition at temperature 60-160 deg. C by using molybdates as catalyst, separation by crystallization, converting part of the residual glucose in the mother liquid after separation by crystallization into fructose through glucose isomerase column, obtaining the miscible liquid of glucose, mannose and fructose, hydrogenation for obtaining the miscible liquid of sorbic alcohol and mannose, wherein the mannitol crystal can be prepared through the crystallization and purification of miscible liquids.

The invention discloses a production method for preparing high maltose syrup and dietary fibers by processing waste residues by means of sweet potato starch. The method comprises the steps of 1, enzyme supplementation and slurry mixing are conducted, wherein alpha-medium temperature amylase is added to potato residues to be mixed to be uniform according to the starch content of the potato residues; 2, gelatinization liquefaction is conducted, wherein uniformly mixed materials are subjected to heating and heat preservation for gelatinization liquefaction; 3, saccharification is conducted, wherein liquefied materials are cooled rapidly, and saccharification is conducted; 4, solid-liquid separation is conducted, wherein filtration is conducted after saccharification is conducted, and saccharified liquid and the potato residues with the starch removed are obtained; 5, the saccharified liquid is subjected to purification, concentration and refining, and the high maltose syrup is obtained; the potato residues with the starch removed are subjected to smashing, screening and drying, and the dietary fibers are obtained. According to the production method for preparing the high maltose syrup and the dietary fibers by processing the waste residues by means of the sweet potato starch, the fresh potato residues are adopted, saccharification is conducted on the starch in the potato residues by means of beta-amylase of the potato residues to produce the high maltose syrup, and the amount of use of enzymes is reduced; meanwhile, the potato residues with the starch removed are further processed to produce the dietary fibers, the production cost is low, the technological process is simplified, the pertinence is high, and the production method is specially suitable for popularization in sweet potato starch production enterprises.

The invention discloses a high receiving rate joint crystallizing method of fructose, mannitol and sorbitol, which comprises the following steps: enzymolyzing starch into glucose; transmitting glucose into fructose through glucose isomerase; separating fructose from glucose through analoging mobile bed; obtaining the component with rich fructose and glucose; crystallizing the fructose; transmitting glucose into mannitol under acid condition based on molybdate as catalyst; separating the mannitol from glucose; blending glucose component and glucose mother liquid to saccharify; combining the glucose component; repeating the epimerism reaction; combining the mannitol and crystallized fructose mother liquid; hydrogenating; obtaining the composite alcohol solution with mannitol and sorbitol; crystallizing; refining to obtain the mannitol crystal.

The invention discloses lactobacillus plantarum NX-1 and application thereof in the preparation of hypoglycemic drugs, and belongs to the technical field of microorganisms. The preservation number ofthe lactobacillus plantarum NX-1 provided by the invention is CGMCC No. 20109. Fermentation supernatant, bacterial suspension and cell disruption substance supernatant, which are not inactivated and inactivated, of the lactobacillus plantarum NX-1 have relatively strong inhibition effects on alpha-glucosidase and alpha-amylase; and the content of glucose in a model body of zebrafish with hyperglycemia can be obviously reduced. The lactobacillus plantarum NX-1 disclosed by the invention has a huge potential application prospect in the aspect of preparing medicines for treating and / or preventingdiabetes.

The present invention discloses a Gynostemma pentaphylla functional yoghurt product and a preparation method thereof. Lactobacillus plantarum HLX37 is added into fresh milk, 3wt.% Gynostemma pentaphyllum leach liquor, sucrose and pure water, and the yoghurt product is prepared by high-temperature fermentation process. The prepared yoghurt product can significantly reduce the damage of rat liver cells caused by high-fat diet, significantly reduce serum cholesterol and glucose levels in hyperlipidemia rats, and has a pharmacological effect in resisting lipid peroxidation in both inactivated and non-inactivated state; meanwhile, the yoghurt product can also significantly improve the immunity of rat intestine. The yoghurt product can be applied to mitigate or reduce the occurrence of high blood lipid, high blood pressure, high blood sugar symptoms for human beings, and can improve the immune function of human body at the same time, playing a good health-care role for human health.

The invention relates to a preparation process and a product of gynostemma pentaphylla health tea, aiming at solving the problems that the conventional health granules use saccharose with heat as a sweetening agent to realize heat increase of a customer and is not suitable for the diabetics, the heart disease patients and the obese patients. The gynostemma pentaphylla and momordica grosvenori health tea contains stevenleaf, momordica glycosides and other active ingredients. The specific preparation method comprises the following steps: processing fresh raw materials by withering, rolling and water removing; adding momordica grosvenori; fermenting; drying with microwave to obtain the gynostemma pentaphylla health tea.

The present invention discloses a diacetylamine aceticacid ethylenediamine large volume injection and its preparation method. It comprises 0.1-1.2% of diacelylamine aceticacid ethylenediamine and 98.8-99.9% of isotonic regulator, buffer, cosolvent and injection water, and can be made into the large injection with 100 ml, 250 ml and 500 ml, can be used for intravenous drip. Its operation is simple and convenient, and does not result in secondary pollution.

The invention discloses a method for preparing dietary fiber flour from sweet potato starch production waste. According to the method, a dietary fiber is prepared from sweet potato residues and liquid waste generated in the sweet potato starch production process; the sweet potato residues and nutrient substances contained in the liquid waste are also utilized to cultivate acetobacter xylinum as a carbon source and a partial nitrogen source, and are fermented to prepare bacterial cellulose; the raw materials are fully utilized; meanwhile, methods for carrying out ultra-low temperature frozen pretreatment on the sweet potato residues and carrying out high-pressure gas impact-assisted mixed enzymolysis are adopted in the preparation process; and the yield of the dietary fiber flour is increased and the purity of the dietary fiber flour is improved. According to the method, the sweet potato starch production waste can be fully utilized; the yield of the dietary fiber is increased, and the purity of the dietary fiber is improved; and the pollution to environment caused by sweet potato starch production is reduced.

The invention relates to an oat cereal beverage with low glucose content and a preparation method of the oat cereal beverage. The preparation method comprises the following steps: preparing oat pulp,and adding liquefying enzyme, saccharifying enzyme, glucose converting enzyme and xylosidase into the oat pulp for enzymolysis at 55-70 DEG C; and performing enzyme inactivation, then removing residues, adding ingredients, performing sufficient stirring, and performing sterilization so as to obtain the oat beverage. The oat beverage disclosed by the invention is pure in flavor, fine in taste, uniform and consistent in tissue state and outstanding in flavor.

The present invention provides a blueberry fruit storage and preservation method. Blueberry fruits with a uniform size, a consistent maturity and no mechanical damages are chosen and directly put into an airtight plastic box. 1-100[mu]mol / L of methyl jasmonate (MeJA) is used to treat the blueberry fruits for a treatment time of 10 h and at a treatment temperature of 20 DEG C, and the treated blueberry fruits are placed at 0-4 DEG C for storage. The blueberry fruit storage and preservation method effectively slows down the ripening and senescence of the blueberry fruits during the storage process, maintains a good fruit quality, and extends the storage period. As a natural agent, the MeJA applied in the blueberry fruit storage has advantages of being low in the processing cost, less in use amount, secure and easy to use, etc.

The invention discloses application of salvia miltiorrhiza extracts in preparing a protein tyrosine phosphatase 1B inhibitor and a drug for preventing and / or treating type 2 diabetes. The salvia miltiorrhiza extracts salvianolic acid C, salvianolic acid A, danshinolic acid C or salvianolic acid A methyl ester can significantly inhibit the activity of protein tyrosine phosphatase 1B, further increase the glucose uptake rate, reduce the plasma glucose levels and prevent and / or treat the type 2 diabetes. The salvianolic acid C, the salvianolic acid A, the danshinolic acid C or the salvianolic acid A methyl ester are used as active ingredients to make a pharmaceutical preparation which can be used as the protein tyrosine phosphatase 1B inhibitor to prevent and / or treat the type 2 diabetes.

The invention belongs to the technical field of aquatic animal nutrition and feed, and particularly relates to a mulberry leaf composite protein source replacing fish meal and a preparation method ofthe protein source. The invention discloses the mulberry leaf composite protein source replacing fish meal, and the protein source comprises the following components: mulberry leaves, soybean meal, cotton meal and DL-methionine, wherein the weight ration of the mulberry leaves, the soybean meal, the cotton meal to the DL-methionine is (14-20%):(40-45%):(39-43%):(0.2-0.4%). The invention also provides the preparation method of the mulberry leaf composite protein source. The protein source can promote the growth of tilapias, and increase the feeding amount and the weight gain rate of cultured animals; can promote the decrease of fat content of liver, and reduce the activity of glutamic oxalacetic transaminase and glutamic-pyruvic transaminase in serum separately; can improve anti-oxidation ability of organisms, reduce the content of malondialdehyde in the serum, and increase the total antioxidant capacity; can significantly improve the lipid metabolism of the cultured animals, and reducethe content of total cholesterol, triglycerides and glucose in the serum; and can improve the economic benefit, and reduce feed cost and breeding cost.

The invention discloses application of novel moderate temperature alpha-amylase, that is the invention discloses application of alpha-amylase AmyM of which the amino acid sequence is shown in SEQ ID No.1, for preparing syrup which is rich in maltohexaose through processingh. The syrup comprises the following components: more than 50% of oligosaccharide(higher than maltotetrose, 8-10% of maltotriose, lower than 6% of malt sugar, and lower than 35% of other kinds of oligosaccharide. When the syrup prepared from the amylase disclosed by the invention is compared with the conventional maltohexaose syrup, the glucose content is lower, the maltohexaose content is higher, the sugar components after enzyme treatment are relative single, and the application range is wider. Due to the good characteristic of the novel alpha-amylase AmyM disclosed by the invention, so that the preparation process of the oligosaccharide is simple, and products are easy to purify.

The invention belongs to the field of tea processing and relates to a kudzuvine flower-honey tea product. The kudzuvine flower-honey tea product is prepared from the following raw material ingredientsin parts by weight: 20-35 parts of kudzuvine flowers, 10-20 parts of ampelopsis grossedentata, 10-20 parts of honey, 5-10 parts of lotus leaves, 1-3 parts of barbary wolfberry fruit and 5-10 parts ofkudzuvine flower concentrated liquor. The kudzuvine flower-honey tea product is obtained by carrying out steps of extracting, mixing, fermenting and drying. According to the invention, by virtue of away of spraying the kudzuvine flower concentrated liquor, the utilization rate of the kudzuvine flowers can be increased, the fragrance of the kudzuvine flowers also can be beneficially enhanced, andthe absorption of the fragrance of the kudzuvine flowers also can be facilitated. A high temperature and high humidity way is adopted, bread yeasts can be autolyzed rapidly, and destruction of the original flavor in tea due to fermentation also can be reduced. By carrying out fermentation treatment on honey, glucose content in the honey is greatly reduced, and the drinking range of a honey product is expanded.

The invention provides a giant salamander nutrition powder product prepared from rhizoma polygonati odorati. The giant salamander nutrition powder product prepared by the steps of preparing 20-40 parts of rhizoma polygonati odorati rhizome, 10-15 parts of saponin rice and 40-60 parts of giant salamander, carrying out high-temperature water extraction and enzymolysis, blending, and drying for later user. According to the giant salamander nutrition powder product, proteins, polysaccharides and flavonoids in giant salamander, rhizoma polygonati odorati and saponin rice are adequately utilized, and the fishy taste produced by giant salamander in a traditional technical process is overcome, so that the giant salamander nutrition powder product has the efficacies of tonifying spleen, nourishing face and yin and the like. According to a method of the invention, the loss of the protein nutrient of giant salamander is avoided, and the giant salamander is subjected to deep processing treatments such as high-temperature processing and enzymolysis, so that the comprehensive processing of giant salamander is realized, the process is easy to control, the industrial production is convenient, and the processing added value of giant salamander is increased. By virtue of hydrolysis through compound cellulose and protease, rhizoma polygonati odorati polysaccharides are rapidly released, the use efficiency of rhizoma polygonati odorati is improved, and the necessary amino acid content in a product is increased. By virtue of germination of saponin rice, the protein content in the raw materials is effectively increased, and the glucose content in saponin rice is decreased; and by virtue of protease degradation, the amino acid content is increased, and antioxidant substances in germinated saponin rice can be adequately utilized.

The invention provides a composition used for adjusting blood sugar. The composition comprises an effective dose of monascine or / and ankaflavin. The invention also provides another composition used for adjusting blood sugar, and the composition comprises an effective dose of a monascus fermentation product obtained via inoculation of culture medium with monascus and further fermentation and preparation. It is confirmed by animal experiments that the composition is capable of adjusting hyperglycemia caused by high fat and high sugar diet effectively, and reducing oxidative stress response and inflammation induced by hyperglycemia effectively. The composition can also be used for reducing AST and ALT values in liver and sarcosine value in kidney synchronously besides reducing of blood glucose concentration, and relieving inflammation of liver and kidney.

The invention relates to the technical field of microorganisms, in particular to lactobacillus fermentum MF423 from rice flour fermentation wastewater and application of the lactobacillus fermentum MF423. The lactobacillus fermentum MF423 fermented rice bran extract disclosed by the invention has an effect of improving insulin resistance in vivo and in vitro. Through determination, on the cell and animal level, the rice bran extract fermented by the bacterium has relatively high antioxidant activity, and can be used for remarkably increasing the consumption of glucose in a culture medium by cells, reducing the blood sugar of mice, remarkably eliminating lipid accumulation of the mice and inhibiting the occurrence of low-grade inflammation, and has important value in subsequent efficient utilization of low-value resource rice bran and application of the rice bran in clinical treatment of the type 2 diabetes mellitus.

The invention discloses a highland barley low-sugar crisp skin moon cake. The moon cake includes the following components in parts by weight: 30-45 parts of highland barley powder, 5-10 parts of low-fat milk powder, 10-15 parts of shortening, 5-10 parts of salted egg yolk, 10-15 parts of xylitol, 5-10 parts of walnut powder, 5-10 parts of honey, 10-15 parts of sesame, 5-10 parts of mung bean powder, and 5-10 parts of lemon juice. According to the moon cake, the highland barley is used as a main raw material of the moon cake, the highland barley is rich in beta-glucan and can reduce the increase of the glucose content in blood, and the xylitol is used to replace white granulated sugar to reduce the sugar content in the moon cake, so that the moon cake is suitable for being eaten by patientswith diabetes, hypertension and hyperlipidemia, and the edible value of the moon cake is improved; the low-fat milk powder and the mung bean powder are added, so that more lysine can be provided forthe moon cake, the lysine content in the moon cake is increased, and the nutritional value of the moon cake is improved; and the lemon juice is added, so that the appetite of consumers can be increased, the greasy feeling of the moon cake can be reduced, and the fruit fragrance is given to the moon cake.

The present invention relates to the field of foods and particularly relates to an auxiliary blood-sugar-lowering type lactic acid bacterium composition and a method for preparing a lactic acid bacterium beverage therewith. The lactic acid bacterium composition comprises the following components in parts by weight: 60-70 parts of skim milk powder, 20-30 parts of corn stigma, 20-25 parts of mulberries, 10-15 parts of guava leaves, 8-10 parts of deep sea spirulina, 0.1-0.3 part of lactic acid bacteria, 6-8 parts of erythritol, 1-2 parts of tripterygium wilfordii powder and 2-3 parts of abelmoschus moschatus seed powder. After the components are fermented, toxicity of the tripterygium wilfordii is removed, and under synergistic actions of the corn stigma, mulberries, guava leaves, deep sea spirulina, tripterygium wilfordii and abelmoschus moschatus, the lactic acid bacterium composition can effectively lower blood sugar and improve blood sugar regulation ability.

The invention relates to the technical field of health food, and concretely relates to small molecular protein peptide health food having hpyerglycemic function and a preparation method thereof. The health food mainly comprises the following raw materials: 70-72 parts of soybean protein oligopeptide, 2-10 parts of a coptis extract product and a dark plum extract product, 0.3-0.6 parts of vitamin C, 0.01-0.06 parts of mineral element zinc, and 0.01-0.06 parts of mineral element magnesium. The synergism of the raw materials can increase the insulin sensitivity and glucose tolerance, reduces glucose content in blood, is sweet and sour, can regulate yin, and has the functions of eliminating dampness by bitter and cool, and alleviating yin deficiency symptom of diabetes, and an auxiliary metabolism mode can keep blood sugar balance of the body. The soybean protein oligopeptide contains a balanced amino acid mode, combination of soybean protein oligopeptide, vitamin C, mineral element zinc and mineral element magnesium can effectively improve the nutrient composition deletion status of the diabetes patients, and can enhance body immunity and mitigates various symptoms of diabetes.

The invention discloses a strain of Lactobacillus plantarum NX‑1 and its application in the preparation of hypoglycemic drugs, belonging to the technical field of microorganisms. A strain of Lactobacillus plantarum NX-1 disclosed by the present invention has a preservation number of CGMCC No.20109. Lactobacillus plantarum NX‑1 inactivated and inactivated fermentation supernatants, bacterial suspensions, and supernatants of cell disruptions have strong inhibitory effects on α-glucosidase and α-amylase; and both can Significantly reduce the glucose content in the zebrafish hyperglycemia model. The Lactobacillus plantarum NX‑1 disclosed by the invention has great potential application prospects in the preparation of medicines for treating and / or preventing diabetes.

The invention relates to the technical field of prevention and treatment of cotton diseases, in particular to application of a gene GhSWEET42 in prevention and treatment of cotton verticillium wilt, and the nucleotide sequence of the gene GhSWEET42 is as shown in SEQ ID NO: 1. The inventor finds that the expression condition of the gene GhSWEET42 is closely related to the infection process of the cotton verticillium wilt through verification in multiple aspects. When the verticillium dahliae infects the cotton root, the glucose content is obviously increased in the colonization process of the verticillium dahliae, and the expression quantity of the gene GhSWEET42 is obviously up-regulated when the verticillium dahliae invades; and subcellular localization and yeast heterologous complementation experiments prove that the gene GhSWEET42 encoding protein is a glucose transporter localized on plasma membranes. The gene GhSWEET42, which is a key gene of verticillium dahliae in cotton infection, is further obtained through an overexpression gene GhSWEET42 and a silence gene GhSWEET42.

The present invention provides a production method for removing lipoprotein from horse serum. The production method for removing lipoprotein from horse serum comprises the following steps: rough filtering of horse serum through sterile gauze; preliminarily filtering a filtrate A through a filtering column; passing a filtrate B through a modified cellulose acetate filter membrane with a pore size of 0.05-1 [mu]m; conducting ultra-filtering by passing an obtained filtrate C through a hollow fiber ultrafiltration column with a molecular weight cut-off lower than 100 kD; placing the filtrate C obtained by the ultrafiltration in C18 resin for chromatography; placing a chromatographic effluent in a reaction tank and adding ethanol for precipitation; adding a Celite 503 adsorbent to a supernatantA; and adding a polysaccharide microsphere adsorbent to a supernatant B to prepare a lipoprotein-removed horse serum finished product. The method is simple and fast, stable in processes and also suitable for mass production, and can effectively remove lipoproteins and fibrin-containing proteins in the horse serum through layer-by-layer filtration and separation.

The invention relates to compound seasoning oil. The compound seasoning oil is prepared from components in parts by mass as follows: 1-20 parts of wasabi, 10-50 parts of an enzymatic hydrolysate of marine fish, 1-10 parts of a dispersant, 1-10 parts of refined honey, 10-30 parts of a condiment, 20-100 parts of linseed oil and 10-50 parts of a spice extract solution. The invention further disclosesa preparation method of the compound seasoning oil. The compound seasoning oil with the linseed oil as base oil is provided in the technical scheme, deep processing of honey is performed with a special process, so that content of glucose in the honey is reduced, enzymatic hydrolysis and release of wasabi flavor substances in the compound seasoning oil are improved, allyl isothiocyanate in the wasabi is retained to the greatest extent and is enabled to have high retaining degree, meanwhile, the seasoning oil has fresh and sweet aroma of the honey and umami of seafood, and linoleic acid in thelinseed oil has a protective effect on pungent flavor substances and chlorophyll in the wasabi.

The invention relates to a process for preparing mannitol by using glucose as raw material, which comprises the steps of, converting glucose solution partly into mannose under acidic condition at temperature 60-160 deg. C by using molybdates as catalyst, separation by crystallization, converting part of the residual glucose in the mother liquid after separation by crystallization into fructose through glucose isomerase column, obtaining the miscible liquid of glucose, mannose and fructose, hydrogenation for obtaining the miscible liquid of sorbic alcohol and mannose, wherein the mannitol crystal can be prepared through the crystallization and purification of miscible liquids.

The invention relates to the field of chemical engineering, in particular to a compound and a preparation method thereof. The compound has high alpha-glucosaccharase inhibitory activity and can be used for preparing blood glucose reduction drugs. According to the preparation method, a double-chalcone type alpha-glucosaccharase inhibitor can be obtained through two-step reaction, and accordingly, reaction steps are simple. In-vitro pharmacological experiments show that the compound has a certain inhibition effect on alpha-glucosaccharase. Cellular level detection shows that the compound does not obviously affect ingestion activities of HepG-2 cells from exogenous glucose; a compound ccy-13 (1 micrometer) can obviously (p<0.05) reduce the glucose content (about 40%) of the cells, close to a positive control group PG (5 micrometers), thereby having high alpha-glucosaccharase inhibitory activity. The compound can be used for preparing the blood glucose reduction drugs.

The invention relates to a preparation method of composite beer syrup, belonging to the technical field of syrup preparation. The method comprises the following steps: inoculating a supernatant obtained by stirring and centrifuging biogas slurry and distilled water into a self-made screening culture medium, culturing, collecting the eluent, mixing the eluent with a liquid in humifuse euphorbia herb stems and a phosphoric acid solution to obtain a fermentation base solution, grinding bagasse, apple peel and the like, uniformly mixing the ground substance with the fermentation base solution, heating to perform fermentation, filtering the fermentation mixture, and carrying out adsorptive decolorization on the filtrate by using activated carbon, thereby obtaining the composite beer syrup. The composite beer syrup has the advantages of reasonable syrup components and high alpha-amino nitrogen content (up to 190-210 mg / L). The glucose content is lower than 8%, and the maltose content is up to 55-58%. The degree of fermentation can be effectively enhanced to 68.7-75.2%.

The invention provides a rhizoma bletillae granule product for protecting intestines and stomach. The rhizoma bletillae granule product is prepared by the following specific steps: taking dried rhizoma bletillae, cooking at high temperature, adding water, mashing, and carrying out enzymolysis by amylase; extracting with water at high temperature, filtering to obtain a filtrate, extracting with ethyl acetate to obtain a solution I, concentrating, carrying out ethanol precipitation, filtering with a gauze to obtain filter residues, and dissolving with water to obtain a rhizoma bletillae extract;taking dry radix astragali, crushing, extracting with water at high temperature, filtering to obtain a filtrate, extracting with ethyl acetate to obtain a solution II, concentrating, performing ethanol precipitation, filtering to obtain filter residues, and dissolving with water to obtain a radix astragali extract; sterilizing orange peel, adding the lactic acid bacteria liquid and water, and fermenting to obtain a mixture; filtering the mixture by a gauze, stirring and mixing the filtrate with the rhizoma bletillae extract and the radix astragali extract under pressurized conditions, filtering, and performing conventional spray drying on the filtrate to obtain the granule product for protecting intestines and stomach. The rhizoma bletillae polysaccharide, astragalus polysaccharide, orange peel flavone and other functional components are utilized to lower components for resistance to mycobacterium tuberculosis and other active components and glucose to the minimum level, thereby facilitating the development of the rhizoma bletillae health food and playing a role in nourishing the stomach.

The invention discloses a health-care beverage capable of reducing blood sugar and uric acid. The health-care beverage is characterized in that the health-care beverage consists of strontium, potassium, sodium, calcium, magnesium, zinc, manganese, selenium and chromium required by human bodies, and each liter of the health-care beverage comprises the following trace elements: the strontium of 0.1-0.3 mg / L, the potassium of 0.1-0.5 mg / L, the sodium of 5-10mg / L, the calcium of 11-13mg / L, the magnesium of 4-6mg / L, the zinc of 3-5mg / L, the manganese of 0.1-0.5 mg / L, the selenium of 0.1-0.4 mg / L and the chromium of 0.1-0.3mg / L. Elements such as the strontium, the potassium, the sodium, the calcium, the magnesium, the zinc, the manganese, the selenium and the chromium required by a human body are added into each liter of the alkaline beverage, so that the alkaline beverage has no toxic or side effect, and is beneficial to reducing the glucose content and uric acid content in the human body while quenching thirst.