13 results about "Structural isomer" patented technology

The objective is to provide a plant activator for soybeans that can increase soybean yield. [Solution] A plant activator for soybeans comprising at least one compound selected from ketooctadecadienoic acid or its derivatives, structural isomers, or salts thereof.

The invention discloses a bimetallic-Salen photocatalyst based on an isomerism effect as well as a preparation method and application of the bimetallic-Salen photocatalyst. The catalyst is synthesized through a solvothermal method, a diamine compound (such as 3, 3 '-diaminobenzidine or 1, 2-diaminobenzene) and a polyaldehyde compound (such as 2, 6-diformyl phenol or 3, 3', 5, 5 '-tetraformyl-4, 4'-biphenol) are used as organic ligands, a plurality of metal acetates (including Sc, In, Zn, Cu and the like) are used as metal sources, and the catalyst is synthesized through a solvothermal method. And the bimetallic-Salen isomer with a one-dimensional chain structure is prepared under a mild condition. The obtained material can form two isomers with zigzag (Z type) and linear (L type) structures according to different coordination orientations. The concept of'coordination oriented isomerization 'provided by the invention realizes accurate regulation and control of photoelectric properties on the molecular level, and provides a new theory and technical route for designing a multi-metal synergistic efficient artificial photosynthesis system. The catalyst material provided by the invention has wide application prospects in the fields of photocatalytic oxygen production, green oxidation reaction, sustainable energy conversion and the like.

The invention provides a method for detecting N-(2-alanyl)-L-glutamine tetramer impurities in a compound amino acid liquid preparation by adopting a liquid chromatography-mass spectrometry technology, and the conditions of liquid chromatography are as follows: a chromatographic column taking amide bonded silica gel as a filler is adopted, a formic acid aqueous solution with the volume ratio concentration of 0.05%-0.3% is taken as a mobile phase A, a mobile phase B is taken as a mobile phase C, a mobile phase D is taken as a mobile phase C, a mobile phase D is taken as a mobile phase C, and a mobile phase D is taken as a mobile phase C; the method comprises the following steps: by taking a chromatographic column as a mobile phase A and a formic acid acetonitrile solution with the volume ratio concentration of 0.05-0.3% as a mobile phase B, eluting by adopting a gradient elution procedure, and the conditions of mass spectrometry are as follows: the ionization form is ESI < + >, and the detection mass-to-charge ratios are 418.1 / 218.1 and 418.1 / 147.1. The method can be used for effectively separating and detecting two alanyl-glutamine tetramer structure isomer impurities in the alanyl-glutamine liquid preparation.

Described herein are compounds and compositions characterized, in certain embodiments, by conjugation of various groups, such as lipophilic groups, to an amino or amide group of an amino acid, a linear or cyclic peptide, a linear or cyclic polypeptide, or structural isomer thereof, to provide compounds of the present invention, collectively referred to herein as “APPLs”. Such APPLs are deemed useful for a variety of applications, such as, for example, improved nucleotide delivery. Exemplary APPLs include, but are not limited to, compounds of Formula (I), (II), (III), (IV), (V), and (VI), and salts thereof, as described herein:wherein m, n, p, R′, R1, R2, R3, R4, R5, R8, Z, W, Y, and Z are as defined herein.

The present application relates to the technical field of dissolved organic matter, and particularly relates to a method for analyzing molecular structure information of dissolved organic matter based on high-resolution tandem mass spectrometry. The method for analyzing molecular structure information of dissolved organic matter based on high-resolution tandem mass spectrometry comprises the following steps: obtaining tandem mass spectrometry data; tracking fragmentation path and identifying functional groups, identifying possible functional group combinations based on neutral loss mass difference between starting point molecules and fragment ions, and tracking fragmentation path; identifying and quantifying isomers, identifying and quantifying isomers of target molecules based on fragmentation path; algorithm evaluation and parameter optimization; structure evolution and statistical analysis. The method for analyzing molecular structure information of dissolved organic matter based on high-resolution tandem mass spectrometry establishes an analysis process from parent ions to structural isomers by constructing fragmentation path, identifying neutral loss combinations and extracting isomer characteristics, and significantly improves the depth and accuracy of molecular structure analysis of dissolved organic matter.

Methods for partial or full-surface sealing of drivable concrete traffic surfaces comprising the following work steps: 1. Substrate treatment with a primer based on aliphatic polyisocyanates and polyaspartic acid ester mixtures 2. Application of a liquid sealing layer based on aliphatic polyisocyanates and polyaspartic acid ester mixtures 3. Application of an adhesive layer based on aliphatic polyisocyanates and polyaspartic acid ester mixtures 4. Sprinkle quartz sand into the bonding layer 5. Application of at least one mastic asphalt wearing course characterized in that polyaspartic acid ester mixtures are used, containing at least i) a polyaspartic acid ester of the structure ii) at least one further amino-functional polyaspartic acid ester of the general structural formula in which R1 and R2 independently represent a methyl group or an ethyl group and X represents a divalent organic residue formed by removing the amino groups from an amino polyether of the general structural formula, which also includes corresponding constitutional isomers and n represents a number from 2 to 8, preferably 2.5 to 6.5 and particularly preferably 2.5 to 4.5.

A method of controlling phytopathogenic diseases on useful plants or on propagation material thereof, which comprises applying to the useful plants, the locus thereof or propagation material thereof a combination of components (A) and (B) in a synergistically effective amount, wherein component (A) is a compound of formula Icompound of formula IwhereinR is hydrogen or methoxy;Q isR1 is hydrogen, halogen or C1-C6alkyl;R2 is hydrogen, halogen, C1-C6alkyl, C2-C6alkenyl, C3-C6alkinyl, C3-C6cycloalkyl-C3-C6alkinyl, halophenoxy, halophenyl-C3-C6alkinyl, C(C1-C4alkyl)=NO-C1-C4alkyl, C1-C6haloalkyl,C1-C6haloalkoxy, C2-C6haloalkenyl, or C2-C6haloalkenyloxy;R3 is hydrogen, halogen, C1-C6alkyl;R4, R5 and R6, independently from each other, are hydrogen, halogen or -≡-R7; with the proviso that at least one of R4, R5 and R6 is different from hydrogen;R7 is hydrogen, C1-C6alkyl, C1-C6haloalkyl or C1-C4alkoxyalkyl; andR8 is hydrogen or methoxy;and agrochemically acceptable salts / isomers / structuralisomers / stereoisomers / diastereoisomers / enantiomers / tautomers and N-oxides of those compounds; and component (B) is a compound selected from compounds known for their fungicidal and / or insecticidal activity, is particularly effective in controlling or preventing fungal diseases of useful plants.

The application discloses a kind of negative electrode slurry for lithium ion battery and its preparation method, the preparation method of the negative electrode slurry includes the following steps: 1) with 3,4'-ODA or 3,4'-ASD and alpha-ODPA as raw material preparation solid component content≤5wt% with amino-terminated polyamic acid prepolymer solution;2) the polyamic acid prepolymer obtained is mixed with negative electrode active material and conductive agent uniformly, add or not add polar solvent, mix evenly to obtain slurry precursor;3) in slurry precursor, add asymmetric structure isomerization dianhydride end-capping agent, stir polymerization reaction, namely obtained;The asymmetric structure isomerization dianhydride end-capping agent is preferably MPDA, 3,3'-ODPA or alpha-ODPA, and the molar ratio of the total amount of all dianhydride in the entire preparation process to diamine is 1:1.The negative electrode slurry can effectively inhibit the expansion effect of negative electrode material, thereby improving the initial efficiency and cycle stability of the battery.

The invention relates to the technical field of soluble organic matters, in particular to a soluble organic matter molecular structure information analysis method based on high-resolution tandem mass spectrometry. The dissolved organic matter molecular structure information analysis method based on high-resolution tandem mass spectrometry comprises the following steps: acquiring tandem mass spectrometry data; fragmentation path tracking and functional group identification: identifying possible functional group combinations based on neutral mass loss difference between starting point molecules and fragment ions, and tracking fragmentation paths of the functional groups; isomer identification and quantification: identifying and quantifying the isomer of the target molecule based on the fragmentation path; evaluating an algorithm and optimizing parameters; and carrying out structural evolution and statistical analysis. According to the dissolved organic matter molecular structure information analysis method based on the high-resolution tandem mass spectrometry, the disintegration path is systematically constructed, the neutral loss combination is recognized, the isomer characteristics are extracted, the analysis process from parent ions to structural isomers is established, and the dissolved organic matter molecular structure analysis depth and precision are remarkably improved.

The invention discloses a cellobiose epimerase mutant with improved lactulose synthesis capability. The mutant CsCE-Q371E of the cellobiose epimerase (CsCE) is taken as a research object, the mutant CsCE-Q371E is constructed through random mutation, the mutant with the structural isomerization catalytic activity remarkably improved is obtained, and the structural isomerization catalytic activity is improved by about 263% compared with the structural isomerization catalytic activity of the CsCE-Q371E. The half-life period (t1 / 2) of the CsCE-IV reaches 478 min and is increased by about 10 times compared with the half-life period (t1 / 2) of CsCE-Q371E (42.68 min). The invention provides a feasible scheme for improvement of cellobiose epimerase, and has important significance for promoting enzymatic industrial synthesis of lactulose.

The invention discloses a mutant CE-FA with improved structural isomerization catalytic activity, and belongs to the field of enzyme engineering. According to the invention, a mutant CsCE-Q371E of cellobiose epimerase (CsCE) derived from Caldicellosipurtor schcharlyticus is taken as a research object, and a mutant CsCE-FA of which the structural isomeric activity is improved by 3.37 times compared with that of the CsCE-Q371E is obtained; under a buffer system with the temperature of 80 DEG C, the pH value of 7.5 and 50 mM of HEPEs, the half-life period (t1 / 2) of CsCE-FA reaches 545 min and is increased by about 10 times and about 8.37 h compared with the half-life period (t1 / 2) (42.68 min) of CsCE-Q371E, a feasible scheme is provided for CE enzyme improvement, and the CsCE-FA has important significance in promoting enzymatic industrial synthesis of lactulose.

The present disclosure addresses the problem of providing a novel compound or a novel agrochemical. Provided is a pyrazole compound represented by general formula (1) (where: A represents iodine, optionally substituted alkynyl, or the like; Z represents an optionally substituted divalent carbocyclic ring or the like; X represents an oxygen atom or carbonyl (C=O); T represents an oxygen atom or a sulfur atom; L represents optionally substituted alkyl or the like; R1 represents a hydrogen atom or the like; R2 represents a hydrogen atom or the like; and R3 represents a hydrogen atom or the like). Also provided is a structural isomer of the pyrazole compound, or a salt of the pyrazole compound or of the structural isomer.

This invention provides a method for producing novel antigen-binding molecules that have the activity to regulate interactions between antigen molecules. [Solution] A method for producing an antibody preparation, comprising the steps of contacting an antibody solution with a reducing agent and, following the contact step, re-oxidizing the antibody, wherein the antibody comprises a first antigen-binding domain and a second antigen-binding domain linked to each other by at least one disulfide bond, the at least one disulfide bond being formed between amino acid residues at EU numbering position 191 in the CH1 region of each of the first and second antigen-binding domains, and the antibody solution comprises two structural isoforms of antibodies differing only by the at least one disulfide bond.