The invention provides a wrinkle-removing essence containing traditional Chinese medicinal herbal extract, and relates to the technical field of skin-care essence. The essence is prepared from the following raw materials in parts by weight: 2-4 parts of safflower extract, 2-4 parts of spicate clerodendranthus herb extract, 2-4 parts of low-molecular collagen polypeptide extract, 2-4 parts of nano-supercritical propolis, 0.5-1 part of protease, 0.5-1 part of aminopeptidase, 1-2 parts of chamomile extract, 1-2 parts of licorice root extract, 1-3 parts of yeast polypeptide, 1-3 parts of oligopeptides -20, 0.5-1 part of carbomer, 0.6-2 parts of aminomethyl propanol, 3-6 parts of propylene glycol, 3-6 parts of 1,3-butanediol, 0.5-1 part of PEG-40 hydrogenated castor oil, 0.5-1 part of blumea balsamifera oil, 0.5-1 part of caprylin, 0.1-0.2 part of methylparaben, 0.1-0.2 part of allantoin, 0.02-0.1 part of EDTA bisodium, 0.03-0.1 part of sodium hyaluronate and 70-100 parts of deionized water. The essence has good permeability, can be easily absorbed, and has effects of removing and resisting wrinkles.