The invention relates to a preparation technique for heavy hollow ingots of all levels between 50 tons to 300 tons, in particular to a manufacturing method for heavy hollow ingots with a movable core and low segregation. The manufacturing method is applicable to the preparation process of all heavy hollow ingots cast by adopting movable cores, including the casting of the hollow ingots of various shapes, specifications and materials; besides utilizing simulation means of computers to reasonably design a mould and a casting system for ingots, the manufacturing method mainly adopts a pore-forming technology with a movable core, an intensive cooling technology for various media at different stages, a movable core protection technology, a technology for controlling the flow of a cooling medium and the temperature of the movable core, an atomizing device for the cooling medium, an early electro slag protection and argon protection technology for molten metal and a technology for protecting the chassis from big temperature variation, thereby guaranteeing the purity of the molten metal and the operability and the stability of the casting technique, mitigating the segregation, controlling the segregation position, locating the segregation band of the hollow ingots in the middle position and increasing the utilization rate and the application range of the hollow ingots.