The invention discloses a freeze-dried snack for preventing alcoholism and protecting liver. The freeze-dried snack for preventing alcoholism and protecting liver comprises the following components in parts by mass: raw pears, seasoning syrup, mature vinegar, apple juice, white radish juice, cabbage core juice, amino acid oral liquid, skimmed milk powder, dried ginger powder, tea leaf powder, licorice powder, edible gelatin, potassium sorbate, sodium erythorbate and calcium citrate. Meanwhile, the invention further provides a preparation method. The preparation method comprises steps of raw pear pretreatment, raw pear block treatment, mixing and stirring, heating, drying and dewatering, and subpackaging and packaging. Compared with a liquid beverage, the freeze-dried snack has greatly reduced satiety, has better eating experience when used for preventing alcoholism, and does not increase the excessive satiety. In addition, in the freeze-dried snack for preventing alcoholism, raw pear blocks are used as a carrier, and effective components in the white radish juice, the cabbage core juice and the amino acid oral liquid added to the raw pears can protect internal organs of people with drunkenness.