The invention discloses special lubrication oil for a heavy-load LNG (liquefied natural gas) engine. The lubrication oil comprises base oil, a viscosity index improver, polymethacrylate, overbased compound magnesium sulfonate, borated polyisobutene succinimide, p,p'-octyldiphenylamine, a liquid hindered phenol type antioxidant, oxymolybdenum dialkydithiophosphate, thiophosphate complex ester, methyl silicone oil and thiadiazole polysulfide, wherein the viscosity index improver is prepared by mixing any of ethylene-propylene copolymers T604, T613, T614, T615 and T618 with a random copolymer of ethylene and alpha-olefin in the mass ratio of 1: 1-8:1. The lubrication oil has an excellent high-temperature detergent dispersing property, excellent high-temperature viscosity remaining capacity, acid neutralization capacity and attenuation resistance, the coking amount is small, the oil-change mileage of the engine is greatly increased, meanwhile, the low-temperature fluidity is good, the engine can work at a lower temperature, and the use requirement of the low-temperature heavy-load LNG engine can be met.