The invention provides a GaN-based enhanced field effect device and a manufacturing method thereof. The GaN-based enhanced field effect device comprises an active region and an isolation region surrounded by the active region, wherein the active region comprises a single crystal substrate, a buffer layer, a channel layer, a barrier layer, an interface control layer, a source metal electrode, a drain metal electrode, a grid metal electrode and a dielectric passivation layer and further comprises a P-type two-dimensional material grid; the P-type two-dimensional material grid is inserted below the grid metal electrode, so the two-dimensional electron gas in the channel below the grid can be effectively depleted, and the GaN-based enhanced field effect device is realized. The P-type two-dimensional material is advantaged in that cavity concentration is high, crystal lattice matching and a low interface state are realized, selective removal from the surface of a gallium nitride material can be realized, and process controllability is good, so threshold consistency of the acquired GaN-based enhanced field effect device is good, and a reliability problem caused by current collapse is well suppressed.