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31results about How to "Lowers histamine levels" patented technology

Fermentation agent for low ergamine salami sausage and method of use thereof

The invention discloses a fermentation agent and the application method for processing low histamine salami sausage, comprising the followings: 1. The selected strains of fermentation agent are CGMCCNo.1923-pediococcus pentosaceus and CGMCCNo.1572-staphylococcus xylosus both without decarboxylase activity; 2. The matching proportion between the CGMCCNo.1923-pediococcus pentosaceus and the CGMCCNo.1572-staphylococcus xylosus is 1:1; 3. The fermentation agent dosage of the pediococcus pentosaceus and the staphylococcus xylosus are 100kg respectively every 100g of mince when processing, the inoculated-pathogen quantity can be up to 1 x 10<7>cfu/g. The adding method is as follow: to make fermentation liquid by mixing the pediococcus pentosaceus fermentation agent and the staphylococcus xylosus fermentation agent with equal ratio and being dissolved in 500g water, spread the fermentation liquid uniformly on the mix mince surface, and mix the mince and the fermentation liquid thoroughly; 4. The preserved preparation used is as follow: the mass ratio to the material mince is salt 3.0%, glucose 1.5%, sodium nitrite 0.015%, and ascorbic acid 0.08%; 5. Using the fermentation agent, preserved preparation and processing technology, the histamine content of salami product is reduced by more than 40% and meets with the food histamine content limitation requirement of the European Union. The invention is tested according to the regulated hygienic standards of cured meat products in the GB2730-2005 hygienic standard for cured meat products, the hygienic state of products meets with the standard, the product flavor and the hygienic safety are better than the traditional technologic product evidently. The invention has the advantages of good application prospect in the aspects of quality improvement and new product development of salami products.
Owner:INST OF ANIMAL SCI OF CHINESE ACAD OF AGRI SCI

Pure traditional Chinese medicine heal-care product granule for treating gastric ulcer and preparation method thereof

The invention discloses a pure traditional Chinese medicine heal-care product granule for treating a gastric ulcer and a preparation method of the pure traditional Chinese medicine heal-care product granule. The pure traditional Chinese medicine heal-care product granule contains the following raw material medicinal components in parts by weight: 18 parts of radix codonopsis, 12 parts of rhizoma atractylodis macrocephalae, 15 parts of poria, 9 parts of radix bupleuri, 5 parts of fructus citri sarcodactyli, 15 parts of cuttle bone, 5 parts of glycyrrhiza, 5 parts of radix notoginseng and 5 parts of fructus aurantii. According to the pure traditional Chinese medicine heal-care product granule for treating the gastric ulcer and the preparation method of the pure traditional Chinese medicine heal-care product granule of the invention, the granule with the effects of invigorating spleen and supplementing qi and soothing the liver and harmonizing the stomach is prepared based on a compatible principle of a traditional Chinese medicine prescription and mainly treats the gastric ulcer, duodenal ulcer, chronic gastritis and gastrointestinal neurosis. Compared with the existing tablets and capsules with the relative effects, the pure traditional Chinese medicine heal-care product granule has the advantages of being smaller in dosage, better in taste, higher in bioavailability, more stable in quality, simpler in production technology, more convenient to take, faster to absorb and the like.
Owner:XIAN FUAN INNOVATION CONSULTATION

Saccharomyces cerevisiae capable of reducing biogenic amine in yellow rice wine and its construction method and application

The invention discloses saccharomyces cerevisiae engineering bacteria capable of reducing biogenic amine in yellow rice wine and its construction method and application, and belongs to the technical field of molecular biology. Through knockout of a PEP4 propeptide gene of saccharomyces cerevisiae, the saccharomyces cerevisiae engineering bacteria having low protease A activity are obtained and can be used for fermentation production of yellow rice wine having low biogenic amine content. Under the premise of no influence on fermentation performances, a result of comparison between the converted offspring saccharomyces cerevisiae engineering bacteria and the parent bacteria shows that after simulative semi-solid state fermentation, main biogenic amine content is reduced, the reduction amounts of tyramine, cadaverine and histamine are maximum and compared with the original bacteria, the saccharomyces cerevisiae engineering bacteria have tyramine, cadaverine and histamine contents respectively reduced by 57.5%, 24.6% and 54.3%; and the screened engineering bacteria have no special requirements on fermentation equipment and conditions, are suitable for equipment and conditions of common wineries, have wide application prospects and can provide important guarantee for safe production of yellow rice wine.
Owner:TIANJIN UNIV OF SCI & TECH

Method for reducing histamine content in high-salt liquid-state soy sauce

PendingCN107518373ALowers histamine levelsFlavor is not affectedFood scienceBranSoya bean
The invention relates to a method for reducing histamine content in a high-salt liquid-state soy sauce. The method comprises the following steps of (1) adding 2.0-4.0% of sodium chloride in the process of making yeast: during making of the yeast, after soybean meal or soybeans are cooked, adding bran and rice bran in the proportion of the bran and the rice bran to the cooked soybean meal or the cooked soybeans being 1 to (0.2-1.0), adding the sodium chloride in the proportion of the sodium chloride to the cooked soybean meal or the cooked soybeans being 1 to (0.02-0.04), performing uniform mixing, performing inoculating with aspergillus oryzae extracts which are 0.02-1.0% of the mass ratio of the soybean meal or the cooked soybeans, making the yeast so as to obtain the hard liquor made with yeast; and (2) when the hard liquor made with yeast is mixed with salt water, adding 1.0-4.0% of ethanol: when the hard liquor made with yeast is mixed with the salt water, adding ethanol being 1.0-4.0% of the total mass ratio of the hard liquor made with yeast and the salt water, performing uniform mixing, performing fermentation by a brewing method of the high-salt liquid-state soy sauce for 60-90 days, and performing squeezing and performing filtering so as to obtain soy sauce crude oil. Through the method disclosed by the invention, the histamine content of the high-salt liquid-state soy sauce crude oil can be reduced by 60% or above, and conventional indexes and the flavor of the soy sauce are not influenced.
Owner:浙江五味和食品有限公司 +2

Dandruff-removing itch-relieving composition and preparation method thereof

The invention provides a dandruff-removing itch-relieving composition and a preparation method and application method thereof. The dandruff-removing itch-relieving composition is prepared from the following raw materials in parts by weight: 4-10 parts of dihydrogen oat alkaloid, 4-8 parts of alanyl glutamine, 5-30 parts of a thickener, 10-25 parts of organic alcohol, 5-10 parts of a surfactant, and 20-60 parts of a dispersing agent. The used raw materials are clear in component, and have little irritation to scalp cells; the dandruff-removing itch-relieving composition containing the dihydrogen oat alkaloid and the alanyl glutamine has a relatively good sterilization effect and anti-allergy effect, nourishes the scalp, slows down the abnormal rapid defluvium of stratum corneum cells of thescalp, and has an obvious itch-relieving effect; in addition, the composition is transparent liquid in appearance, and can be directly added into existing shampoo under room temperature to prepare dandruff-removing itch-relieving shampoo; development of new products, especially transparent shampoo products, by manufactures is convenient; the problems that existing dandruff-removing itch-relievingfunctional components cannot be directly added and / or preparation of the transparent shampoo is difficult are effectively solved.
Owner:甄旭东

Method for preparing trepang oil capsules from trepang internal organs

The invention discloses a method for preparing trepang oil capsules from trepang internal organs. The method comprises the following steps of (1) taking fresh trepang internal organs, cleaning taken fresh trepang internal organs, draining cleaned trepang internal organs, cutting the drained trepang internal organs into broken pieces, adding water, table salt, magnesium chloride and polypropylene fiber nonwoven fabric strips, and performing uniform stirring to obtain a mixture; (2) adding the mixture obtained in the step (1) into a high-pressure reactor, performing heating, then releasing pressure, and lowering the temperature; (3) performing pressure-reduced evaporation on the mixture obtained in the step (2) so as to obtain solids, and performing carbon dioxide super critical extraction so as to obtain coarse trepang oil; (4) washing the coarse trepang oil obtained in the step (3) sequentially with a sodium carbonate aqueous solution and hydrochloric acid, and then performing washingwith clean water; and (5) stuffing the trepang oil obtained in the step (4) in soft capsules so as to obtain the trepang oil capsules. Through the adoption of the method disclosed by the invention, the trepang oil can be efficiently extracted, and trepang oil products being very low in histamine content are obtained. The method is reasonable in technology and advanced in technique, and can be widely used for processing and utilizing the trepang internal organs.
Owner:荣成海锐芯生物科技有限公司

Method for controlling content of histamine in fermented aquatic products

The invention discloses a method for controlling the content of histamine in fermented aquatic products. The method comprises the following steps of: 1) cleaning a fresh aquatic product which serves as a raw material and then keeping the raw material fresh at a low temperature; 2) adding an appropriate quantity of salt and As3.942 protease into the cleaned aquatic product which serves as the raw material, and adding an appropriate quantity of lactic acid bacteria strains which serve as a biological control agent of the histamine at the same time, mixing uniformly, then placing the mixture into a fermentation container, and covering and tightly sealing the fermentation container, wherein the inoculum concentration is controlled to be 10<6> to 10<8> cfu / mL, and the used amount of an enzyme preparation is controlled to be 50,000 to 150,000 IU / kg in the raw material; and 3) transferring the fermentation container to a fermentation room for fermenting to obtain the fermented aquatic product, namely fish sauce, wherein the fermentation temperature is controlled to be between 18 DEG C and 22 DEG C, and the fermentation time is controlled to be 40 to 60 days. The method is simple and easy to implement; the conventional natural fermentation process is replaced by an enzyme engineering fermentation technology, and the lactic acid bacteria strains serve as the biological control agent, so that the fermentation period is shortened from six months to 40 to 60 days, and the production efficiency is improved; and harmful infectious microbes are prevented from generating decarboxylase to produce the histamine in the process of natural fermentation, so that the histamine is eliminated or degraded, and the yield and safety of the product are improved.
Owner:ZHEJIANG OCEAN UNIV

A strain of Saccharomyces cerevisiae capable of reducing biogenic amines in rice wine and its construction method and application

The invention discloses saccharomyces cerevisiae engineering bacteria capable of reducing biogenic amine in yellow rice wine and its construction method and application, and belongs to the technical field of molecular biology. Through knockout of a PEP4 propeptide gene of saccharomyces cerevisiae, the saccharomyces cerevisiae engineering bacteria having low protease A activity are obtained and can be used for fermentation production of yellow rice wine having low biogenic amine content. Under the premise of no influence on fermentation performances, a result of comparison between the converted offspring saccharomyces cerevisiae engineering bacteria and the parent bacteria shows that after simulative semi-solid state fermentation, main biogenic amine content is reduced, the reduction amounts of tyramine, cadaverine and histamine are maximum and compared with the original bacteria, the saccharomyces cerevisiae engineering bacteria have tyramine, cadaverine and histamine contents respectively reduced by 57.5%, 24.6% and 54.3%; and the screened engineering bacteria have no special requirements on fermentation equipment and conditions, are suitable for equipment and conditions of common wineries, have wide application prospects and can provide important guarantee for safe production of yellow rice wine.
Owner:TIANJIN UNIV OF SCI & TECH

A composition with anti-inflammatory synergistic effect and application thereof

The invention discloses a composition with anti-inflammatory synergistic effect, which is composed of licochalcone A and licorice flavonoid B, and the two are in the molar ratio (1-7):(1-3) preparation. Compared with licochalcone A or licorice flavonoid B, the anti-inflammatory activity of the composition provided by the invention is significantly enhanced, and it is superior to other flavonoid compounds and compositions, indicating that there is an obvious anti-inflammatory synergistic effect between the two . It has been confirmed by different inflammatory models that when licorice chalcone A and licorice flavonoid B are combined, the anti-inflammatory synergistic effect is prominent, and it is licorice flavonoid B that significantly affects the anti-inflammatory activity of licorice chalcone A or other compositions, overcoming the existing There is a technical prejudice that the content of licochalcone A is higher or significantly higher than that of licorice flavonoid B to have significant anti-inflammatory activity. In particular, when the combination ratio of licochalcone A and licorice flavonoid B is 1:1, the anti-inflammatory activity of the composition is the highest, and has wide application value in the field of anti-inflammatory.
Owner:新疆维吾尔自治区中药民族药研究所
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