4results about How to "Small application restrictions" patented technology

The invention provides a functional lung partition adjustment method and device, equipment and a medium, and the method comprises the steps: obtaining a functional lung image of a target object and an initial functional partition result corresponding to the functional lung image; constructing a graph structure model based on an initial function partitioning result and functional lung imaging; wherein the graph structure model comprises nodes, edges and weights of the edges; each node is used for representing an initial functional area, the edge is used for connecting two adjacent nodes, and the weight of the edge is used for indicating the similarity between the two adjacent nodes; and based on the graph structure model, adjusting the initial function partitioning result to obtain a target function partitioning result. According to the embodiment of the invention, the method can achieve the adjustment of the plurality of initial function regions based on the graph structure model through the similarity between the initial function regions, obtains a plurality of target function regions with continuous regions and regular boundaries, and further obtains a target function region result with low discreteness and small application limitation.

The utility model relates to a rotary transmission structure, belongs to the technical field of information transmission, and solves the problem that application limitation of one-way transmission is more in the prior art. The utility model discloses a rotary transmission structure which is composed of a transmission ball, a contact rod and a base. The contact rod and the transmission ball rotate relatively; one end of the contact rod is fixed on the base, and the other end is in point contact with the transmission ball; the plurality of contact rods are uniformly distributed along the circumference; the contact points of the contact rod and the transmission ball are on the circumference of the same circle, and the ratio of the diameter of the circle to the diameter of the transmission ball is 0.5-0.8. The multi-directional transmission device can realize multi-directional transmission, and is simple in structure and less in application limitation.

This invention discloses a combined safety valve core structure with pilot function and its usage method, relating to the field of safety valve technology. The main valve core is slidably and sealed to the inner wall of the valve body, while a secondary valve core is slidably and sealed to the central through-hole. A lower spring is sleeved around the secondary valve core. A main valve core seat is located at the bottom of the valve body. A pressure chamber is formed between the upper end face of the main valve core and the top of the inner wall of the valve body. The bottom medium inlet of the valve body is connected to the pressure chamber via a branch pipe. An upper spring is located within the pressure chamber, and a secondary valve core seat is located at the connection between the branch pipe and the top of the valve body. This invention achieves a synergistic effect of "secondary valve core pilot triggering and main valve core rapid response" through the coaxial nesting design of the main and secondary valve cores, combined with a dynamic balance mechanism between the upper and lower spring forces and the medium pressure. This invention possesses the rapid response characteristics of a direct-start safety valve, while also having the advantages of a pilot-operated safety valve, such as good sealing performance, pilot characteristics, and minimal impact from back pressure.

The application belongs to the technical field of gene therapy, and particularly relates to an AAV capsid protein mutant targeting glial cells and application thereof. The AAV capsid protein mutant is constructed by inserting a polypeptide with glial cell infection characteristics between N589 and R590 of an AAV-DJ capsid protein amino acid sequence, and exhibits enhanced transduction and targeting in inner ear basal membrane supporting cells, and has the function of enhancing supporting cell transduction in the cochlear basal membrane of newborn and adult mice, thereby being capable of solving the problem of low transduction efficiency of AAV in the cochlear basal membrane supporting cells of adult mice, and providing a potentially available tool for gene therapy of deafness genes positioned in supporting cells by Chen et al. GJB2 and the like.