The invention relates to a preparation method of an isostatic pressing microcrystalline graphite product. The isostatic pressing microcrystalline graphite product comprises the following components by weight: 35-50% of microcrystalline graphite, 10-25% of artificial graphite, 10-25% of electrically calcined pitch coke and 30-40% of modified coal tar pitch. The isostatic pressing microcrystalline graphite product is obtained by the steps of pretreating raw material, burdening, kneading, rolling, fragmenting and pulverizing, preforming, performing isostatic compaction, roasting, dipping, performing heat treatment under high temperature and the like. The unique part in the method is the usage of the natural microcrystalline graphite as a main aggregate, the resource can be used in a reasonable mode, high temperature graphitization heat treatment at more than 2500 DEG C on the product is not required, so that preparation period can be shortened, and the energy consumption is greatly reduced. The prepared isostatic pressing microcrystalline graphite has the advantages of high volume density, mechanical strength, low resistivity, fine and compact structure, and isotropy.