Thyrotoxicosis is called as hyperthyroidism, and is a disease with the symptoms of palpitation, sweating, eating and urination time increase and weight loss caused by body hypermetabolism and sympathetic nervous excitement as too many thyroid hormones are synthesized and released from thyroid. Most patients have symptoms of exophthalmos, palpebral oedema, hypopsia and the like. The medicine is prepared from medicines including horsetail, atractylodes macrocephala, dandelion, duckweed, cordyceps sinensis, arabic cowry shells, honeysuckle, roots of kudzu vine, polygonum multiflorum, felwort, desmodium triquetrum, angelica sinensis, patrinia, artemisia anomala, prepared rehmannia roots, fructus viticis, chlorite schist, cimicifuga foetida, kelp, rhizoma anemarrhenae, pumex, reed rhizome, cuttle bone, cape jasmine, turtle shells, prunella vulgaris, seaweed, pipewort, concha haliotidis, moutan barks, oyster, houttuynia cordata, callorhinus ursinus and hawksbill. Due to the effects of the combined medicines, a synergistic effect can be achieved, and thus hyperthyroidism can be effectively treated.