2 results about "Interphase Cell" patented technology

The application provides a method and system for simulating a microtubule self-organizing process in interphase cell polarization, and belongs to the fields of computational biology and physical technology; the method comprises the following steps: abstracting a cell as a two-dimensional circular domain, abstracting a microtubule as a line segment with a fixed direction starting from a point-like centrosome in the circular domain, abstracting a polar factor space distribution as a concentration field in the circular domain, and performing a time-dependent evolution process simulation by coupling centrosome positioning, microtubule length evolution and polar factor space distribution dynamics. The application can comprehensively investigate the feedback regulation mechanism of the microtubule self-organizing process in interphase cell polarization.

A B S T R A C T The invention relates to a combination therapy comprising administering a mitotic- phase (M-phase) cell cycle arresting compound and a modulator of an interphase cell cycle checkpoint to a subject and delivering ionizing radiation to the same subject for the treatment of a tumor. Provided is for (M-phase) cell cycle arresting compounds, modulators of an interphase cell cycle checkpoint and ionizing radiation for use in such treatments, as well as methods of the treatment involving the use of (M-phase) cell cycle arresting compounds and modulators of an interphase cell cycle checkpoint and ionizing radiation.