The invention discloses a preparation method of oriental cherry
powder with activity of inhibiting generation of AGE. The method comprises low-temperature processes of cleaning, countercurrent extraction,
filtration, concentration, sterilization,
freeze drying, sieving and the like. Countercurrent extraction and low-temperature membrane treatment are combined for extraction of oriental cherry, and a low-temperature process is adopted in the whole process and totally-closed intensive
continuous production is adopted. According to the method, the contents of total flavonoids, caffeoyl glucose (1-O-caffeoyl-beta-D-glucopyranoside) and
quercetin glucoside (
quercetin-3-O-beta-D-glucopyranoside) contained in the oriental cherry are fully reserved, separated and enriched, active ingredients are fully extracted, the transfer rate is high, the yield of the active ingredients of the prepared oriental cherry
powder is high, and the prepared oriental cherry
powder is suitable for industrial production. A green membrane material is adopted, the safety is high, and active ingredients are effectively enriched, so that the prepared oriental cherry powder has a remarkable effect of inhibiting the generation activity of AGEs, the generation inhibition rate of AGEs reaches 58% (when the concentration is 100 micrograms per milliliter), and IC50 reaches 67 micrograms per milliliter.