The invention discloses a mulberry compound conditioning health-maintaining cake which comprises the following components by weight part: 30-50 parts of mulberry dried fruit, 0.1-10 parts of silkworm pupa protein peptide powder, 5-15 parts of black sesame, 5-15 parts of semen juglandis, 0.1-15 parts of donkey-hide gelatin, 0.1-10 parts of honey and 15-30 parts of compound adhesive. According to the concept of Chinese traditional health-maintaining and health-care through the traditional Chinese medicine and on the basis of the principle of traditional drug matching, the mulberry dried fruit is taken as a main ingredient, the drug property mutual-requiring auxiliary materials, such as the black sesame, the semen juglandis, the donkey-hide gelatin, the honey, and the like, are finely selected, the silkworm pupa protein peptide powder with oxidation-resisting and immunity-boosting functions is specially added, the activities of the functional factors, such as, anthocyanin in the raw materials are effectively reserved, and the compound adhesive preparation comprising folium mori polysaccharide is adopted, so that the prepared mulberry compound conditioning health-maintaining cake is convenient to eat, is excellent in color, fragrance, flavor and nutrition, and has the effects of regulating blood sugar level, tonifying qi and yin, nourishing liver and kidney, relaxing bowel and blacking hair and improving eyesight.