35results about How to "Good resistance to photobleaching" patented technology

The invention belongs to the field of organic fluorescent porous materials, and provides a silfluorenyl conjugated porous polymer and a preparation method thereof, using 3,6-dimethoxy-2,7-diethynyl-9,9-dimethyl The silfluorene-based conjugated porous polymer is obtained through the Sonogashira coupling reaction at 75°C to 85°C through the Sonogashira coupling reaction. The polymer has a three-dimensional structure, spherical and tubular, and has a hollow structure. The fluorescence intensity will increase with the extension of the ultraviolet lamp (365nm) irradiation time. It has a light-induced fluorescence enhancement effect and has good photobleaching resistance. sex. The polymer will be widely used in fluorescence analysis, tracking detection, biological imaging and other aspects. At the same time, the preparation method is simple, the synthesis route is short, the operation is very convenient, the raw material preparation technology is mature, and the yield is high, which has important guiding and reference functions for the development of similar fluorescent dyes or organic fluorescent polymers.

The invention provides a near infrared fluorescent probe substrate material of rare earth ion nano alkali metal rare earth fluoride and a preparation method of the near infrared fluorescent probe substrate material. The chemical formula of the material is MRe (1-x-y) Rm (x) YbyNdzF4, wherein the M is one or more of Li, Na and K, the Re is one or more of Gd, La, Y and Lu, and the Rm is one or more of Er, Tm, Tb and Ho. The material is prepared through a solvothermal method and a hydro-thermal method, efficient near infrared light of 980 nm of a wave band can be obtained under the excitement of infrared light of 730 nm and 800 nm of wave bands, and upconversion fluorescence visible to near infrared light wave bands can be obtained under the excitement of infrared light of 980 nm and 800 nm of wave bands. Therefore, the material can serve as an upconversion fluorescence probe and a downconversion fluorescence probe for fluorescence imaging after being packed and subjected to surface decoration, and the material can serve as magnetic resonance imaging when a substrate contains magnetic element Gd.

The invention relates to a phosphorescent iridium complex with a lysosome targeting function and its preparation method and use and belongs to the technical field of organic photoelectric materials. The phosphorescent iridium complex comprises a C^N ligand, a metal core and an alkyl chain-containing auxiliary ligand and has a structural formula shown in the description. The phosphorescent iridium complex can be excited by visible light, produce emission light in a near infrared area and reduce an excitation light source-caused damage to a biological sample and has deep tissue penetrating depth. The phosphorescent iridium complex has good photobleaching resistance and realizes long-term effective observation of cell tissue. The phosphorescent iridium complex can be used in the field of lysosome labeling and bioimaging, has a simple chemical structure and good biocompatibility and is a good lysosome targeting phosphorescent probe.

The invention particularly relates to a synthesis method of tellurium-containing semiconductor nanocrystals. The chemical formula of the tellurium-containing semiconductor nanocrystal is shown as CdTexA1-x, wherein 0<x≤1, A is Se or S; the steps are as follows: preparation of the precursor; mixing the precursor to obtain a reaction solution; reacting the reaction solution for 1s-3h , cooling and precipitating to obtain the tellurium-containing semiconductor nanocrystal. Conventional, stable and low-toxic drugs are used in the synthesis process of the method, and the cost can be saved by more than 50%. The method is safe, easy to operate and has good repeatability. The synthesized Te-containing nanocrystals almost cover the visible-near-infrared light region; the size distribution is uniform, the fluorescence efficiency is high, the half-height width is narrow, and the photobleaching resistance is good; it has high application value in laboratory and industrial production .

The invention discloses a method for preparing synthetic sulfur-phosphorus co-doped graphene quantum dots and relates to preparation of nano materials. The method comprises the following steps: respectively putting citric acid monohydrate, sodium phytate and anhydrous sodium sulfate into a container, further adding deionized water, and stirring and dissolving so as to obtain a clear solution; transferring the obtained clear solution into a high-pressure kettle, performing hydrothermal treatment, and naturally cooling to a room temperature so as to obtain a dark yellow solution; transferring the obtained dark yellow solution into a centrifugal tube from the reaction kettle, and removing relatively large suspended granules through centrifugation so as to obtain supernate; performing suctionfiltration on the obtained supernate after centrifugation, and transferring the obtained yellow filtrate into a dialysis bag for dialysis; freezing the solution after dialysis, and further performingfreeze-drying on the obtained solid product, thereby obtaining the sulfur-phosphorus co-doped graphene quantum dots. The citric acid is adopted as a carbon source, the sodium phytate is adopted as a phosphorus source and the sodium sulfate is adopted as a sulfur source for the first time, and S,P-GQDs are synthesized through a simple one-step hydrothermal method.

The invention discloses a blue fluorescent silver nanocluster, a preparation method and application thereof, and belongs to the technical field of fluorescent nanomaterials. The present invention uses histidine as the reducing agent and protective agent, silver nitrate solution as the matrix, and prepares the fluorescent silver nanocluster solution through microwave synthesis. Reproducible without the use of commonly used reducing agents or other chemical reagents. The obtained silver nanoclusters have good stability, good water solubility, and low toxicity. At the same time, they have high sensitivity responses to copper ions and iron ions at different pH values, and can be applied to detect copper or iron ions with high sensitivity and high selectivity. , and the detection process is simple and fast, and the detection result is highly accurate, and can be used to construct a sensing system for detecting copper ions and iron ions.

The invention relates to a method for preparing a yellow fluorescent bioimaging material, comprising: step S1: preparing the yellow fluorescent bioimaging material; step S2: performing column chromatography purification on the yellow fluorescent bioimaging material prepared in step S1. It also relates to a yellow fluorescent bioimaging material. The invention also relates to the application of a yellow fluorescent bioimaging material. The advantage is that the yellow fluorescent bioimaging material is prepared by using the solvothermal method with small chemical molecules as precursors; the yellow fluorescent bioimaging material has the characteristics of high fluorescence efficiency and good photobleaching resistance; the material can be used as a biological probe label Reagents for cell and in vivo imaging.