41results about How to "Great stability" patented technology

The present invention provides an immunoconjugate formulation that is substantially free of particles, the immunoconjugate formulation comprising: an immunoconjugate and one or more excipients selected from the group consisting of: sucrose, polysorbate 20, polysorbate 80, cyclodextrin, dextrose, glycerol, polyethylene glycol, mannitol, sodium chloride, and an amino acid, wherein the formulation is a buffered aqueous solution having a pH of 4.5 to 7.6. The present invention also provides an immunoconjugate formulation that is substantially free of aggregates, the immunoconjugate formulation comprising: an immunoconjugate and one or more excipients selected from the group consisting of histidine, sucrose, glycine and sodium chloride, wherein the formulation is a buffered aqueous solution having a pH of 4.5 to 7.6. The present invention further provides an immunoconjugate formulation that is substantially free of both particles and aggregates.

Distinctive components that enable high-throughput, whole-animal screening are described. These components can be used individually or in various combinations. A staging chip strains off the excess fluid that the input animals are immersed in, increasing their density (number of animals in a given volume) and rapidly bringing them close to other fluidic components. A microfluidic sorter is adapted to isolate and immobilize a single, physiologically active animal in a selected geometry. A multiplexed micro-chamber chip receives single animals and the microchamber chip includes individually addressable screening chambers for imaging, incubation and exposure of individual animals to selected chemical compounds. An imaging structure generates sub-cellular, high-resolution images of the physiologically active animals. A well-plate interface chip is used to deliver elements from a compound library to a single output of the chip.

A chimeric, carboxy-terminal truncated hepatitis B virus nucleocapsid protein (HBc) is disclosed that contains an immunogen for inducing the production of antibodies to malarial proteins. An immunogenic malarial epitope is expressed between residues 78 and 79 of the HBc immunogenic loop sequence. The chimer preferably contains a malaria-specific T cell epitope and is preferably engineered for both enhanced stability of self-assembled particles and enhanced yield of those chimeric particles. Methods of making and using the chimers are also disclosed.

Methods and computer readable media for performing a compositional reservoir simulation of a subterranean hydrocarbon-bearing reservoir is provided. Reduced variables for flash computations are utilized with a methodology of conditional stability testing for achieving optimal efficiency of phase behavior computations in a compositional reservoir simulator. A least abundant phase is selected as primary variables for a primary phase and a secondary phase is selected for a more abundant phase to ensure stability by not dividing by a value near zero due to the selection of the primary phase as being associated with phase which is the least abundant. A bounded interval may be used to limit solution changes in reduced variable algorithms to achieve greater stability of algorithms. Stability tests may be performed during flash computations using reduced variables by employing a direct residual form based on the definition of the reduced variables and the tangent-plane distance condition.

The invention discloses a white light organic electrofluorescence device which comprises RGB and includes an underlay, an anode layer and a cathode layer. An electrode is positioned on the surface of the underlay. An organic function layer equipped between the anode layer and the cathode layer includes a luminous layer at least and sends out white light under external power drive. The luminous layer comprises of RGB luminescent materials. A composite material layer consisting of blue and light fluorescent material, red, green and blue phosphorescence material and main host material sends out efficient white light under the external power drive. The invention adopts the method of doped phosphorescence material, adjusts proper doped concentration, and prepares high-performance white light and other color organic electrofluorescence device by utilizing the main and the object materials with luminescence principle.

The invention relates to a drinking straw which is sealed and/or re-sealable at the ends and which can serve as a supply container for a dry food product or which can comprise multiple parts, and to its use.

A differential oscillator circuit including first (10) and second (20) branches each including the series arrangement, between high (VDD) and low (VSS) supply potentials, of a transistor (4, 5) and bias means (2, 3, 8, 9) for imposing a determined current through the current terminals of the transistor. The transistors are interconnected so as to form a crossed pair of transistors, the most positive current terminal of each transistor (on the “drain” side) being connected to the control terminal of the other transistor of the crossed pair. This differential oscillator circuit further includes an electro-mechanical resonator (6) connected to the crossed transistor pair on the “drain” side, as well as a capacitive element (7) connected to the crossed transistor pair on the “source” side. The capacitance value of the capacitive element is selected so as to be less than a maximum value above which relaxation of the oscillator circuit can occur and thereby prevent relaxation of the oscillator circuit.

A consensus-based power control apparatus is provided, which includes a real power control module and a reactive power control module. A real power consensus signal between a first power generating apparatus and a second power generating apparatus is provided and a frequency restoration signal is generated according to the real power consensus signal, thereby allowing the real power control module to generate a real power output signal. A reactive power consensus signal between the first power generating apparatus and the second power generating apparatus is provided and a voltage differential restoration signal is generated according to the reactive power consensus signal, thereby allowing the reactive power control module to generate a reactive power output signal. Therefore, the invention can control real power and reactive power input signals (i.e., actual real power and reactive power outputs) of the first power generating apparatus in a grid system.

Provided is a method of operating a nonvolatile memory device to perform an erase operation. The method includes applying a composite pulse including a direct current (DC) pulse and a DC perturbation pulse to the nonvolatile memory device to perform the erase operation.

Drill sleeve (1) for a dental drill (70) having a hollow and cylindrical shape and a longitudinal axis A, a circular inner surface (10) for guiding the dental drill (70), and an outer surface (15) intended to be inserted into a template (50). The outer surface (15) of the drill sleeve (1) has at least one longitudinal flattened or concave area (20, 120), the circular inner surface (10) is essentially parallel to the longitudinal axis A, and the drill sleeve (1) is thin-walled.

The present invention relates to new crystalline salt forms of flibanserine which have valuable pharmacological properties, to a process for their manufacture, to pharmaceutical formulations containing them and to their use as medicament.

A magnetic tool holder includes a body having a bottom and side walls defining an elongate central channel, wherein the bottom defines a first plane and ends of the side walls define a second plane, wherein the body further includes side edges laterally extending from said side walls in the second plane, and outer side walls extending from the side edges back to the first plane; and at least one magnet in the elongate central channel, the at least one magnet having a tool securing surface positioned substantially coplanar with the second plane. The outer side walls configured in this manner greatly increase the magnetic flux in both planes or surfaces of the holder.

A golf club set which comprises a plurality of golf clubs having shafts of different tapered section lengths, at least two golf club shafts of the set having differing taper lengths and preferably differing taper angles, the tapered section length of the shaft increases as the shaft length increases for each club throughout the set, and vice versa. Accordingly, each shaft throughout the set of shafts has a distinct taper length. The distinct variable taper clubs provide efficient energy transfer, better feel perception by the golfer, greater ball flight distance, less ball flight dispersion, and greater club stability.

The present invention provides parathyroid hormone and/or parathyroid hormone-related protein analogs, compositions thereof and methods thereto.

The invention belongs to the technical field of heterogeneous catalysts, and particularly relates to a monodisperse porous organic metal polymer material and a preparation method and application thereof. The polymer is prepared by taking homogeneous double carbene iridium, palladium, gold, copper, cobalt and manganese compounds as monomers and aromatic hydrocarbon as a comonomer in a manner of adding a cross-linking agent and carrying out Friedel-Crafts alkylation under the catalysis of Lewis acid. The polymer can be used for catalyzing hydrogenation cyclization of levulinic acid to prepare gamma-valerolactone, or catalyzing oxidative dehydrogenation of polyol and derivatives thereof and carbohydrate compounds to efficiently prepare lactic acid and derivatives thereof, and dehydrogenationcoupling of alcohol compounds and amine to efficiently prepare pyrrole and derivatives thereof. The polymer material completely holds intrinsic high activity and high selectivity of a homogeneous catalyst precursor and has the characteristics of heterogeneous catalysis stability and easiness in recovery, so that biomass can be converted into various fine chemicals with high efficiency, high selectivity and a large amount; the catalyst can be recycled for multiple times and has a good industrial application prospect.

The present invention relates to gels prepared from novel anionic block copolymers of mono alkenyl arenes, diphenylethylenes and conjugated dienes, and to blends of such block copolymers with oils. The block copolymers are selectively hydrogenated and have mono alkenyl arene/diphenylethylene end blocks and conjugated diene mid blocks. The block copolymer may be combined with oils and other components to form the gels of the present invention.

An oral composition comprising an active component and an adhesive film forming component comprising bleached shellac and shellac wax for the treatment of teeth.

The invention relates to a strip steel wire drawing production line and an assembly-line wire drawing process thereof. The production line comprises a base plate, a material placing device, a guidingdevice and a wire drawing device; the material placing device and the guiding device are sequentially installed on the base plate from left to right, and the wire drawing device is arranged at the upper end of the guiding device and installed on the base plate; the material placing device comprises a material feeding mechanism and a material collecting mechanism, the wire drawing device comprisesa lifting frame, a rotary motor, a non-woven fabric roller brush, a vibration frame, a bump, a rotating shaft and a rotating motor, and the guiding device comprises a working table, a first mounting plate, positioning plates, a second mounting plate, pressing springs, extrusion frames, linear sliding rails, rotating shafts and pressing blocks. The strip steel wire drawing production line and the assembly-line wire drawing process thereof can solve the problems that in the strip steel wire drawing process, the surface of strip steel is uneven, the movement stability is poor, the use range is small, and the adjustability is poor, can achieve the function of automatic wire drawing on strip steel, and has the advantages that the flatness of the strip steel is high, the stability is high, the use range is wide, and the adjustment is flexible.

The invention discloses a strain loading system for micro-nano material multi-field joint characterization. A sample stage is fixed to the top end of a base body by spring screws, wherein piezoelectric ceramic is fixed to the upper end of the bottom of the base body, a loading stage is stuck in a metal support groove, a metal support is fixed to a groove in the right side of the sample stage by metal support screws, an electrode pressing sheet is fixed to the upper end of the sample stage, the electrode pressing sheet is in close contact with an electrode on the loading stage to form good electrical contact, a pressure head is fixed in the metal support groove, and the metal support is fixed in the top surface of the piezoelectric ceramic. Strain loading on micro-nano materials in multiple characterization devices is realized; an electrical measurement system has the characteristics of simple structure, reliable performance, simple and convenient installation, convenient operation and wide application scope, can be applied to all one-dimensional or two-dimensional nanomaterials with the length greater than 5 microns, and can be used together with instruments such as various optical microscopes, electron microscopes, spectrometers and synchronous radiometers for multi-field coupling testing.

The invention discloses a chemiluminescent immunoassay kit for quantitatively detecting digoxin. The chemiluminescent immunoassay kit is characterized in that the chemiluminescent immunoassay kit includes a reagent R1, a reagent R2 and a reagent R3, wherein the reagent R1 is a suspension containing streptavidin magnetic particles, the reagent R2 is a solution containing a digoxin monoclonal antibody marked by a chemiluminescent marker, and the reagent R3 is a solution containing digoxin derivatives marked by coupling markers. According to the chemiluminescent immunoassay kit provided by the invention, the digoxin is a small molecular substance, thus detection is conducted through the principle of a competitive method, the time and cost are saved, and the kit has the high specificity of animmune reaction, further has the high sensitivity of a luminous reaction and has the advantages of high sensitivity, high specificity, wide linear range, good reagent stability, easy and convenient operation and easy automation; a preparation method provided by the invention is simple in technology, and the kit is long in validity period and relatively low in cost; rapid detection is convenient torealize, the requirements for instruments are simple, and fully-automatic operation is convenient to realize.

The invention relates to a green environment-friendly sewage treating agent. The invention is characterized in that the sewage treating agent is mainly prepared by mixing the following components in parts by weight: 20-25 parts of composite iron, 15-20 parts of dibromonitrilo propanamide, 8-12 parts of polyaluminum chloride, 30-35 parts of bentonite, 18-26 parts of straw and 3-8 parts of sodium chloride. The sewage treating agent has the advantages of favorable sewage treatment effect, high bactericidal property, low toxicity, low cost and accessible raw materials.

The present invention discloses an iron-based cathode material for a sodium-ion battery, which comprises a Na₃Fe₂(SO₄)₃F material and a carbon-based material embedded into the bulk structure of Na₃Fe₂(SO₄)₃F material. The weight percentage of the carbon-based material is ranked between 1% and 10%. The present invention also provides a method for preparing the above-mentioned iron-based cathode material for a sodium-ion battery, and a corresponding sodium-ion full battery using the Na₃Fe₂(SO₄)₃F-based cathode material. The Na₃Fe₂(SO₄)₃F cathode material ensures desired electrochemical sodium storage performance, involving high specific sodium storage capacity, improved cycle stability and superior rate performance in comparison with that of various pristine Na_xFe_y(SO₄)_z materials. The actual operating potential of the reported sodium-ion full battery in the present invention is significantly higher than the output potential of existing commercial sodium-ion full batteries, and the increase in battery energy density is also achieved.

The invention discloses a goose egg incubation device. The goose egg incubation device comprises an incubation box, wherein a temperature adjusting device is connected with the incubation box; supporting rods are arranged in the incubation box, and multiple rotating rods are arranged on each supporting rod; each rotating rod is connected with a rotating motor, a timing device and an installation disk, and an upper incubation disk, a plurality of reflectors, fixing rods, pushing air cylinders, a lower incubation disk and illuminating light bars are arranged on each installation disk; the lowerincubation disks and the upper incubation disks are each provided with multiple incubation grooves which are evenly distributed, and fixing devices are arranged in each incubation groove; humidification pipes are arranged on both inner side surfaces of the incubation box, and an atomizer is arranged on each humidification pipe; and a ventilation pipe is arranged on the top surface of the incubation box, and a suction pump is arranged on the ventilation pipe. The goose egg incubation device not only can improve the safety of egg turning, but also has the advantages that the stability of goose egg placement is good, the working efficiency is high, use is convenient, an application range is wide, the incubation efficiency of goose eggs is high, the adjustment rate is high, and the heating rate is high.

The invention relates to a preparation method of a wearable gas-liquid difunctional alcohol electrochemical sensor, and belongs to the field of wearable gas-liquid difunctional alcohol electrochemicalsensors. The preparation method comprises the following steps: manufacturing a screen printing plate of a silk-screen printing three-electrode sensor array; carrying out silk-screen printing on the silk-screen printing slurry on a flexible substrate to manufacture a sensor array; modifying an electroactive material; and modifying the solid electrolyte to obtain the wearable gas-liquid bifunctional alcohol electrochemical sensor. The wearable gas-liquid bifunctional alcohol electrochemical sensor prepared by the invention shows extremely strong substrate applicability and environmental applicability, and still shows considerable sensing stability in certain stretching and bending states as a flexible sensor.

A device (10) is provided for the handling and transportation of an eyeball (1) including: at least one base body (2) including a first housing seat or cavity (4) for housing at least partially the eyeball; at least one retaining element (3) including at least three fins (13) for retaining the eyeball in the first housing seat or cavity; and at least one lid (5) removably combinable with the base body.

The invention relates to turning-over assisting equipment for nursing a patient in a general surgery department. The turning-over assisting equipment comprises a support, wherein a supporting plate is fixedly connected to the center of the outer surface of the support, a bed plate is fixedly connected to the top end of the support, leg exercise mechanisms are arranged at the front end and the rear end of the right side of the upper surface of the bed plate separately, a transmission box is fixedly connected to the bottom of the left end of the supporting plate, a transmission device is arranged in the transmission box, and a hinged plate is hinged to the left end of the bed plate. The stability of the equipment is improved by arranging the transmission device with a self-locking function, the transmission device drives a turning-over mechanism and a massage mechanism to work, the production cost of the equipment is reduced, the comfort degree of the patient lying in bed is improved by arranging the massage mechanism, rehabilitation of the patient is accelerated by arranging the leg exercise mechanisms, and the functionality and practicability of the equipment is improved; and by arranging a lifting mechanism, angle adjustment of the hinged plate is achieved, use requirements of different patients are met, and the application range of the equipment is widened.

Container made of a plastic material, provided with a base including a standing ring forming a support flange and a diaphragm extending from the standing ring to a central portion, the diaphragm being capable of standing in an outwardly-inclined position, wherein the diaphragm connects to the standing ring at an outer junction forming an outer articulation of the diaphragm; wherein the diaphragm connects to the central portion at an inner junction forming an inner articulation of the diaphragm; whereby the diaphragm is invertible with respect to the standing ring from the outwardly-inclined position to an inwardly-inclined position; and wherein, in the outwardly-inclined position, the diaphragm has an outer curved portion and an inner curved portion of opposite curvatures.

A laser-scanning microscope having an illumination-beam path and a detection-beam path and a microscope objective. A component for generating a plurality of scanning beams from at least one illumination beam is located in the illumination-beam path. A wedge-shaped, light-transmitting first component part provided in the illumination beam path generates spatially offset partial beams, the scanning beams being generated at the first component part by multiple reflections at an at least partially partially-reflecting surface. The microscope has a one-dimensional scanner for moving the scanning beams over a sample in the illumination beam path. The scanning beams have at least partially relative to one another a non-zero angle upstream of the objective in the illumination direction. The scanning beams can intersect at least partially in the objective pupil of the microscope objective. Additional compensation elements are provided for the scanning beams to compensate for a spectral dispersion and/or the beam direction.

The invention discloses a CXT liquid fluorescent whitening agent and a preparation method thereof, and belongs to the field of whitening agents. The CXT liquid fluorescent whitening agent comprises a fluorescent whitening agent acid precipitation substance, polyol amine and polyol. During preparation, the CXT fluorescent whitening agent acid precipitation substance, the polyol amine and the polyol are used as raw materials to be added into a reaction kettle, and uniform stirring is performed; the temperature is increased to 80-100 DEG C, and after the materials are dissolved, clarified and transparent, negative pressure evaporation is performed to remove 30-50% of water; and finally, the temperature is reduced to 40-45 DEG C by cooling, and filtering is performed to obtain the CXT liquid fluorescent whitening agent. The whitening agent is easily soluble in water, has relatively wide temperature stability, can be stored for a long time, supports automatic and continuous use, and is safe and environment-friendly.

The invention provides an energy storage system and method for preparing methanol by using methanol synthesis waste gas. A hydrogen outlet of an electrolytic bath is communicated with a methanol reactor A, and an oxygen outlet of the electrolytic bath is communicated with a waste heat boiler; the input end of the decarburization tower is connected with methanol synthesis waste gas, the carbon dioxide output end is connected with the reaction end inlet of the methanol reactor A, the separated gas outlet of the separation device is connected with the methanol reactor B, and the methanol outlet outputs methanol; a purge gas conveying pipeline is arranged on a pipeline between a separated gas outlet of the separation device and an inlet of the methanol reactor B and is used for being connected with a furnace side inlet of the waste heat boiler; the methanol reactor A is communicated with a waste heat boiler, and the waste heat boiler is connected with a heat absorption end inlet of the methanol reactor A after acting through a turbine to form a circulating energy storage loop. Wind energy, waste gas generated in methanol synthesis and the like are converted into methanol, energy is stored in the chemical energy storage mode, the energy density is high, long-term storage can be achieved, and the application range is wide.