The invention discloses a nitrogen-doped mesoporous carbon-coated Titanium dioxide composite photocatalyst, a preparation method and use thereof. The preparation method comprises the steps of: dissolving an organic ligand and Ti(OC3H7)4 in a mixture of methanol and DMF at a certain ratio, performing a hydrothermal reaction, centrifuging and drying to obtain a Titanium-based metal organic framework (Ti-MOF); pyrolyzing the obtained Ti-MOF under an inert atmosphere, and oxidizing the same for etching to obtain a nitrogen-doped mesoporous carbon-coated Titanium dioxide composite photocatalyst. The obtained composite photocatalyst not only facilitates the adsorption, enrichment and mass transfer of low concentration VOCs, but also efficiently degrades VOCs under sunlight. It has high degradation activity and stability when performing photocatalytic removal of VOCs in the presence of visible light, is simple in synthesis, low in preparation cost, and has strong potential for the use in environmental protection.