The invention discloses a device and a method for preparing slurry liquid by utilizing seawater. The device comprises a seawater pretreatment device, a reverse osmosis device, a slurry stirring pool and the like, wherein the seawater pretreatment system is provided with an active carbon filter and a nanofiltration membrane filter, the reverse osmosis device consists of a plurality of RO (Reverse Osmosis) components, an EDI (Electrodeionization) equipment is used for removing residual Na<+> ions and Cl<-> ions, and a disincrustant in a storage tank, ultrapure water and an electromagnetic valve control switch form maintenance of the reverse osmosis device. According to the method disclosed by the invention, natural seawater flows into the seawater pretreatment system by being pressurized by a booster pump, water after treatment passes through the reverse osmosis device by being pressurized by a high-pressure pump, and produced pure water and bentonite are stirred to prepare the slurry liquid. In addition, the pure water passes through the EDI deionization equipment to produce the ultrapure water use as domestic water for offshore exploration operation, so that the materials produced in the method are used according to the needs and work according to respective ability, and therefore, factor restriction that offshore exploration is limited by a platform space, load, fresh water transportation, fresh water preparation cost and the like is broken through, and the exploration cost is effectively lowered. Furthermore, a maintenance system with the unique design ensures that the service life of the RO components is longer.