The invention discloses a microneedle patch and a preparing method thereof, and belongs to the microneedle technology for medical cosmetology. The microneedle patch comprises a needle layer and a lining layer, and the needle layer is connected with the lining layer, wherein the needle layer is prepared from, by weight, 100 parts of degradable polymer materials, 5-10 parts of cosmetic function molecules and 1-2 parts of enhanceosome. A microneedle array can pierce through the skin, the polymer materials in the array can be degraded in the skin and are harmless to the human body, the cosmetic function molecules dissolved in the polymer materials can be released and directly act on the interior of the skin, and thus the effects of replenishing water to the deep layer, reducing wrinkles and beautifying the skin are achieved. The preparing method of the microneedle patch comprises the steps that a vacuum jetting method is adopted for injecting a polymer solution into a micropore cavity of amicroneedle mold, after the polymer solution is cured, the needle layer is obtained, one side of the needle layer is coated with dissoluble binder, then a layer of gelatin is poured, and after the gelatin is formed, the cured microneedle patch is taken out of the microneedle mold.