The invention relates to the technical field of composite material gas cylinders, in particular to a satellite composite gas cylinder end socket and a manufacturing method thereof. The satellite composite gas cylinder end socket comprises a shell and a connector, wherein the shell and the connector are welded through electron beams; the connector comprises a connector area and a shoulder reinforcing area; the shell comprises a gradual transition area, an equal-wall-thickness film area and a barrel area; and the shoulder reinforcing area is smoothly welded to the gradual transition area, and the gradual transition area is smoothly and gradually connected with the equal-wall-thickness film area. The two materials of TA1 pure titanium and TA3 titanium alloy are adopted, the requirements for high elongation at break and high plasticity of the low-cycle fatigue life of a plastic lining of the end socket shell are met, meanwhile, the requirement for high strength of rigid constraint of the end socket connector is met, the problems of damage, failure and the like of bulging, fracture, buckling, fatigue cracks, permeation and the like of the plastic lining in the fatigue cycle of a gas cylinder are solved, and the satellite composite gas cylinder end socket has the advantages of ultra-thin wall, light weight, high structural precision, good strain displacement matching performance with a composite layer, long low-cycle fatigue life and the like are achieved.