55 results about "Ω-3 fatty acids" patented technology

The present invention relates to a nutritional supplement for administration to children. The supplement comprises a protein component, a carbohydrate component, and a fat or lipid component which further comprises a source of DHA. The supplement has an ω-6:ω3 fatty acid ratio of about 6:1 or less. The present invention also relates to a method of providing nutrition to a pediatric subject comprising administering to the subject a nutritional supplement comprising a protein component; a carbohydrate component; and a fat or lipid component, which further comprises a source of DHA, wherein the composition has an ω-6:ω-3 fatty acid ratio of about 6:1 or less.

Recombinant expression of fat-1 gene of Caenorhabditis elegans in a wide variety of cells, including cells of Arabidopsis thaliana and Saccharomyces cerevisiae, produces a polypeptide having ω-3 desaturase activity.

A multiphase culturing process for high density heterotrophic microalgal growth uses crude glycerol as the primary carbon source and produces ω-3 fatty acids. The process uses multiphase growth conditions that decouple the phases of increasing cell density and increasing cell size and fatty acid production. The entire process is integrated with biodiesel production.

The present invention relates to compositions, kits and methods for the administration of various vitamin, mineral and nutrient compositions, and in a specific embodiment, the compositions, kits and methods may utilize or include vitamin D, iodine, vitamin B1, vitamin B6, vitamin B12, vitamin B2, vitamin B9, vitamin B3, vitamin E, vitamin A, vitamin C, iron, zinc, copper, magnesium, omega 3 fatty acids and one or more pharmaceutically acceptable carriers.

A dietary supplement system including three general components is provided. The first component is the fatty acid component and this includes sunflower seeds (containing omega 6 fatty acids), flax seed (containing omega 3 fatty acids) and powdered oils (containing omega 3 or omega 6 fatty acids and generally produced from sunflower oils). The weight ratio of omega 6 fatty acids to omega 3 fatty acids is 10:1 to 1:1, with 10:1 to 5:1 being preferred for normal animals and 2:1 to 1:1 being preferred for animals which have fatty acid responsive conditions. The second component is the GI component, which is used for facilitating animal gut health. This component includes prebiotics, probiotics and immunoglobulin (typically from albumin concentrate). The third component is the breed specific component and can include vitamins, minerals, additional fatty acids, antioxidants, amino acids, palatants, and nutraceutical additives.

The present invention relates to methods and nutritional compositions for the prevention and treatment of cachexia and anorexia. The methods of the invention comprise administering a composition comprising effective amounts of ω-3 fatty acids such as alpha-linolenic acid, stearidonic acid, eicosapentaenoic acid, docosapentaenoic acid, docosahexaenoic acid or mixtures thereof; of branched-chain amino acids valine, leucine, isoleucine or mixtures thereof; with or without reduced levels of tryptophan and 5-hydroxytryptophan; and of antioxidant system selected from the group comprising beta-carotene, vitamin C, vitamin E, selenium, or mixtures thereof.

A multiphase culturing process for high density heterotrophic microalgal growth uses crude glycerol as the primary carbon source and produces ω-3 fatty acids. The process uses multiphase growth conditions that decouple the phases of increasing cell density and increasing cell size and fatty acid production. The entire process is integrated with biodiesel production.

The present invention relates to an improved method for the specific production of unsaturated ω-3 fatty acids and a method for the production of triglycerides having an increased content of unsaturated fatty acids, in particular ω-3 fatty acids having more than three double bonds. The invention relates to the production of a transgenic organism, preferably a transgenic plant or a transgenic microorganism, having an increased content of fatty acids, oils or lipids having Δ6 double bonds due to the expression of a Δ6-desaturase from Primulaceae. The invention additionally relates to expression cassettes containing a nucleic acid sequence, a vector and organisms containing at least one nucleic acid sequence or an expression cassette. The invention further relates to unsaturated fatty acids and triglycerides having an increased content of unsaturated fatty acids and use thereof.

A composition comprising (a) one or more ω-3 fatty acids selected from DHA, DPA and EPA, (b) uridine or its equivalent, and (c) a methyl donor, useful in the treatment of a person having characteristics of a prodromal dementia patient. The characteristics include e.g. a level of more than 350 ng Total-tau per litre cerebrospinal fluid (CSF), and a weight ratio of abeta-42 / Phospho-tau-181 of less than 6.5 in CSF.

The invention relates to the processing of substances that are not soluble, or soluble with difficulty, in water, in such a manner that, introduced into water or oil, these substances can yield a clear solution and can be easily integrated with finest homogeneous distribution into foodstuff, cosmetics, pharmaceuticals, and nutrient solutions. To achieve that, the invention provides a concentrate, consisting of an active substance from the group, which includes an algae oil, an essential oil, a terpene, phosphatidylserine, an ω 3 fatty acid, lanolin, a linoleic acid triglyceride, citral or tea tree oil, and a surplus amount of a polysorbate with at least two and half times the weight of the active substance.

The present invention relates to the field of methods for purifying fatty acid ethyl esters. According to the present invention, a method for obtaining a ω3 fatty acid ethyl ester, such as EPA and DHA, each as a high purity product at a high yield is provided. In the method according to the present invention, a raw material fat including EPA and DHA is treated with a lipolytic enzyme and ethyl-esterification is performed as needed; the treated substance is fractionated into a glyceride fraction and a free fatty acid fraction; a fraction comprising more EPA ester and a fraction comprising DHA ester are obtained from the respective fractions; the fraction comprising more EPA ester is purified to prepare a high-purity EPA ester; and the fraction comprising more DHA ester is purified to prepare a high-purity DHA ester.

A Cynara scolymus extract with a high content of caffeoylquinic acids, and a composition containing the Cynara scolymus extract with a Phaseolus vulgaris extract. The composition is useful in reducing obesity as it reduces cholesterol, triglycerides and blood glucose by sensitising the cells to insulin. This combination, when taken before meals, reduces the appetite, leading to a reduction in body weight. The extracts are preferably formulated in Oenothera biennis oil, fish oil, or oils rich in unsaturated ω-3 fatty acids.

The present invention can provide a nutrition composition useful for patients with renal diseases, which has an effective prophylactic or improving effect for various symptoms of malnutrition, inflammation, arteriosclerosis, abnormal lipid metabolism and oxidative stress, associated with renal diseases, or for diabetic nephropathy.The nutrition composition of the present invention m contains one or more kinds of free amino acids selected from the group consisting of valine, leucine, isoleucine and histidine, and a lipid comprising ω-3 fatty acid and ω-6 fatty acid at a weight ratio (ω-6 fatty acid to ω-3 fatty acid) of 0.5-5.5. In addition, the composition further contains a soybean protein or a hydrolysate thereof together with the aforementioned lipid or instead of the aforementioned lipid.

The invention relates to a method for the production of multiply-unsaturated fatty acids in an organism, into which nucleic acids have been introduced, which code for polypeptides with Δ-5 elongase activity. Said nucleic acid sequences, optionally with further nucleic acid sequences, coding for polypeptides for the biosynthesis of fatty acids and lipid metabolism, are advantageously expressed in the organism. Nucleic acid sequences coding for a Δ-6 desaturase, a Δ-5 desaturase, Δ-4 desaturase and / or Δ-6 elongase activity are particularly advantageous and, advantageously, said saturases and elongases are derived from Thalassiosira, Euglena or Ostreococcus. The invention further relates to a method for the production of oils and / or triacylglycerides with an increased content of long-chain, multiply-unsaturated fatty acids. A particular embodiment of the invention is a method for the production of unsaturated ω-3 fatty acids and a method for the production of triglycerides with an increased content of unsaturated fatty acids, in particular, of Δ-3 fatty acids with more than three double bonds. Also disclosed is the production of a transgenic organism, preferably a transgenic plant, or a transgenic microorganism with increased content of ω-3 fatty acids, oils or lipids with ω-3 double bonds as a result of the expression of the elongases and desaturases employed in the above method, preferably in combination with ω-3 desaturases, for example a ω-3 desaturase from fungi of the family Pythiaceae such as the genus Phytophtora, for example, the genus and species Phytophtora infestans, or a ω-3 desaturase from algae such as the family Prasinophyceae, for example, the genus Ostreococcus and, particularly, the genus and species Ostreococcus tauri or diatomaceæ such as the genus Thalassiosira and, particularly, the genus and species Thalassiosira pseudonana. The invention also relates to the nucleic acid sequences, nucleic acid constructs, vectors and organisms containing the nucleic acid sequences and / or the nucleic acid constructs and transgenic organisms containing said nucleic acid sequences, nucleic acid constructs and / or vectors. A further part of the invention relates to oils, lipids and / or fatty acids produced according to the above method and use thereof and, furthermore, unsaturated fatty acids and triglycerides with an increased content of unsaturated fatty acids and use thereof.

An optimized nutrient fatty acid composition capable of using as food, skin care, hair care and media for delivery of drugs and nutrients through mucous membrane, skin and parenterally for humans, pets and farm animals, with a ratio of omega 6 fatty acid to omega 3 fatty acids ranging from 1:1 to 1:1.25 stabilized with vitamin E 0.8-4mg / ml. More specifically a stable fatty acid composition with 50-70% of the total fatty acids as essential and, or semi essential fatty acid of which 25-35% omega 3 fatty acids, 25-35% as omega 6 fatty acids and 20-30% as monounsaturated fatty acids is capable of optimization of bodily functions, maintenance of health, prevention of diseases, promotion of healing, delay aging, and treatment of diseases caused by imbalance in omega 3 and 6 fatty acid ratio in diet and nutritional support for pregnant and lactating women, growing children, senior citizens, sports persons, obese and over weight on calorie restricted diet.

Nutrient compositions comprising botanical extracts and an omega 3 fatty acid as well as methods of their use for treating, inter alia, autism or apraxia and / or ameliorating one or more symptoms thereof are disclosed. The use of such compositions for enhancing cognitive function and / or one or more aspects thereof, or for treating stroke or seizures and / or ameliorating one or more symptoms thereof are also disclosed.

This invention relates to compositions for delaying aging. The compositions comprise branched-chain amino acids and whey protein, and combinations thereof, containing the same, such as L-leucine, L-isoleucine, L-valine, lactoferrin, and β-lactoglobulin. The compositions are heat stable when dissolved in water at near neutral pH. The compositions are palatable and suitable for delivering orally administrable anti-aging agents such as ω-3 fatty acids, coenzyme Q10, xanthophylls, L-arginine, and L-glutathione.

The present invention provides food products, nutritional programs, and methods for meeting nutritional needs of subjects with dementia and related cognitive disorders. In one embodiment, the invention provides a food product comprising a reversibly sealed container and a soup, wherein the soup is in the container and comprises a total volume of 200-2000 mls, a vegetable or meat component, 300 to 2500 calories, a macronutrient caloric distribution comprising: 20-80% fat, 10-45% protein, and 10-65% carbohydrate, about 2% to about 40% medium chain triglycerides, omega 3 fatty acids in an amount of 100 to 2000 mg and less than 20 solid food particles having a volume greater than about 20 cm3. Such food products, when administered to affected subjects, can positively impact (i) nutritional status; (ii) quality of life; (iii) disease course; (v) the demand for assistance from a care giver; (vi) subject compliance with a nutritional plan using the food product, and (vii) ease of monitoring compliance by the caregiver for verification.

The invention discloses an optimized nutrient food for optimization of bodily functions and thereby maintenance of health, prevention of diseases and delaying aging. The optimized nutrient food includes about 28 % to about 36 % of protein, about, 17 % to about 26 % of dietary fiber, about 6 % to about 10 % of omega 3 fatty acid, about 6 % to about 10 % of omega 6 fatty acid, about 4 % to about 8 % of omega 9 fatty acid, about 2 % to about 6% of saturated fat, about 4 % to about 13 % of starch / sugar, about 6 % to about 10 % of vitamins and minerals, about 2 % to about 5 %, by weight of water and, a ratio of omega 3 fatty acid to omega 6 fatty acid ranging from about 0.75:1.25 to about 1.25:0.75. Methods of preparation of the optimized nutrient food as well as methods of treatment administering the optimized nutrient food are provided.

The invention relates to a compound and administration of the compound to mammals containing salsalate in a nanofied form to reduce inflammation. This compound and administration may be combined with caffeine, omega 3 fatty acids, sodium bicarbonate, and / or simvastatin to further benefit that administration.

A composition and a method of treatment utilizing a combination of statins (or HMG-CoA reductase inhibitors), a class of drug used to lower cholesterol levels by inhibiting the enzyme HMG-CoA reductase, with mixtures of an omega-3 fatty acid formulation containing about 90% or more omega 3 fatty acids by weight including a combination of Eicosapentaenoic acid (EPA), Docosapentaenoic acid (DPA) and Docosahexaenoic acid (DHA) in a weight ratio of EPA:DHA of from 5.7 to 6.3, wherein the sum of the EPA, DHA and DPA represent about 82% by weight of the total formulation and about 92% of the total omega 3 fatty acid content of the composition are taught.

The invention provides a halophytes omega 3 fatty acid desaturase gene and its expression vector and the said gene transformed cell and plant. The said gene expressed excessively in plants can increase the ª‡-linolenic acid content of leaf, can increase the cold-resistant, salt-tolerant and antimycotic ability, and can promote nutritious value of vegetable. That antisense suppression of the said gene expression in vivo plant can reduce ª‡-linolenic acid content, and can promote the plant high temperature resistance. The invention relates to chimeric gene construction with eukaryon expression promotor, and chimeric gene transformed host cell and recombination and transformation method. At same time, the invention provides a method for cultivating transgenic plant in which the gene is expressed excessively or antisense suppressed.

A composition comprising (a) one or more ω-3 fatty acids selected from DHA, DPA and EPA, (b) uridine or its equivalent, and (c) a methyl donor, useful in the treatment of a person having characteristics of a prodromal dementia patient. The characteristics include e.g. a level of more than 350 ng Total-tau per liter cerebrospinal fluid (CSF), and a weight ratio of abeta-42 / Phospho-tau-181 of less than 6.5 in CSF.

Combinations of one or more anti-obesity drugs with mixtures of an omega-3 fatty acid formulation containing about 90% or more omega 3 fatty acids by weight comprised of a combination of Eicosapentaenoic acid (EPA), Docosapentaenoic acid (DPA) and Docosahexaenoic acid (DHA) in a weight ratio of EPA:DHA of from 5.7 to 6.3, wherein the sum of the EPA, DHA and DPA comprise about 82% by weight of the total formulation and about 92% of the total omega 3 fatty acid content of the composition for the reduction of body weight in cardiovascular disease patients (CVD) and diabetics.

The invention discloses a nutritional grass carp feed with linseed meal. The feed is characterized by being prepared from following raw materials including, by weight, 20-23 parts of rapeseed cake, 19-24 parts of the linseed meal, 1-3 parts of detoxified cotton protein, 14-17 parts of pea straw, 15-18 parts of broad bean straw powder, 16-19 parts of pod shells of petits pois, 12-14 parts of chicken manure, 10-13 parts of milk powder, 8-12 parts of sweet potato powder, 12-16 parts of sweet corn, 13-15 parts of trichosanthes kirilowii, 14-18 parts of angelica sieboldi, 0.3-0.5 parts of brandisia hancei, 0.2-0.4 parts of loquat flowers, 0.1-0.3 parts of rhodiola rosea, 0.2-0.5 parts of fructus sphaerophysa salsula, 3-6 parts of additives and a proper amount of water. In the invention, the linseed meal, which is rich in fibers and [omega]3 fatty acid, is added to the feed so that the feed can reduce cholesterol. Meanwhile, with addition of Chinese herbal medicines, such as the brandisia hancei, the loquat flowers, the rhodiola rosea, the fructus sphaerophysa salsula and the like, the feed can enhance immunity of grass carp, can enhance health of the grass carp and cold-resistant and diseases-resistant capability of the grass carp, thereby ensuring the grass carp to go through winder successfully and increasing a safe coefficient of overwintering breeding.

The invention discloses a coarse fiber cookie and a manufacturing method thereof. The coarse fiber cookie is prepared from, 150-200 parts of flour, 20-30 parts of oat, 15-30 parts of flaxseeds, 10-20 parts of egg liquid, 75-90 parts of butter, 35-50 parts of dried cranberry, 20-30 parts of fresh milk and 60-70 parts of sugar. The coarse fiber cookie is crisp in mouthfeel, full-bodied in fragrance, free of any man-made additive, natural and healthy, by adding the low-sugar, high-nutrition and high-energy oat and the flaxseeds rich in fiber and omega 3 fatty acid, gastrointestinal motility can be promoted by matching other raw materials, convenience is brought to defecation, lipid and blood glucose are reduced, and the demand for health of people is met.

Disclosed herein is a method for feeding low doses of algae to cattle to increase the level of omega 3 polyunsaturated fatty acids including docosahexaenoic acid (DHA) and eicosapentenoic acid (EPA) in commercial cattle feeding environments. The method of increasing the level of omega-3 fatty acids in cattle which comprises feeding the cattle between about 0.05 and 0.8 pounds per day of algae.