111 results about "Basal lamina" patented technology

A device permits effective engagement of micro-needles with a cutaneous layer thereby to permit for a substance to pass effectively to the cutaneous layer. A flexible or non-flexible material supports an array of micro-needles for receiving the surface of the cutaneous layer so that the proximal ends of the micro-needles pierce to effect a passage of a substance with the micro-needles to the cutaneous layer. A passageway or bladder acts on the substrate to cause the proximal ends of the micro-needles to pass to the cutaneous layer for passage of a substance associated with the micro-needles to the cutaneous layer. The bladder includes apertures located about and spaced from the micro-needles such that suction transmitted though the apertures. The micro-needles are mounted with a movable first substrate. In one form, the first substrate includes a surface with concavities and the micro-needles are mounted in the concavities, and the apertures are located in the concavities. In another form the surface is substantially flat. There can be a third layer spaced relative to the second substrate layer at least partly forming a chamber between the second layer and third layer. There can be a biasing device for urging the first substrate from the cutaneous layer.

Wrinkles are cosmetically removed from a superficial area of mammalian skin tissue having an epidermal layer, a basal layer, and a dermal layer, by irradiating the dermal layer through the basal layer, the irradiation being selected to be absorbed by a chromophore in the dermal layer such that collagen present in the dermal layer is heated, while the basal layer remains intact so as to substantially inhibit contact of the dermal layer with ambient air.

A mat having a base layer that is bonded to a top layer. The base layer of the mat includes a plurality of depressions along the bottom surface of the base layer, wherein the depth of the depressions does not exceed the depth of the base layer. The orientation of the depressions on the bottom surface of the mat is such that there is a greater concentration of depressions along the edges of the mat. The top layer of the mat is preferably a layer of carpet tuft. In operation, the depressions of the mat suction the mat to the surface onto which the mat is placed once an initial force is applied to the mat, such as a footstep or vehicular traffic.