The invention discloses a manufacturing method of a precise 3D glass plate. The method is characterized by comprising the following steps: S1, the preparation of glass water; S2, compression molding;S3, high-temperature flame polishing; S4, annealing; S5, detection; S6, fine trimming; S7, polishing; and S8, tempering. The invention further discloses the precise 3D glass plate manufactured according to the manufacturing method of the precise 3D glass plate. According to the manufacturing method of the precise 3D glass plate disclosed by the invention, traditional process glass processing is combined with an existing electronic 3D glass processing process, the precision which cannot be achieved by glass produced by a traditional pressing and pressure blowing method is achieved, the defectsthat a glass product blank obtained by roughening plain glass in existing electronic 3D glass processing is high in height, large in cost and low in amplitude can be overcome, and the method of the invention has the advantages of low cost, high precision, high product percent of pass, high production efficiency and long service life.