Traditional Chinese medicine soap with skin protection and bacteria inhibition efficacy is prepared from, by weight, 10-14 parts of liquorice, 12-16 parts of lonicera japonica, 28-34 parts of selfheal, 29-35 parts of radix saposhnikoviae, 26-30 parts of rhizoma chuanxiong, 14-22 parts of saponin, 21-27 parts of mugwort, 16-26 parts of ginger peel, 28-36 parts of bupleurum chinense, 26-30 parts of radix notoginseng, 26-30 parts of flos hibisci, 19-24 parts of cactus, 19-24 parts of herba menthae, 22-28 parts of white gourd kernels, 28-32 parts of cacumen tamaricis, 28-32 parts of gynura aurantiaca, 12-17 parts of pteris semipinnata, 12-17 parts of herba kalimeridis, 17-23 part of flos chrysanthemi indici, 17-23 parts of desmodium triquetrums, 23-30 parts of herba plantaginis, 19-26 parts of white hyacinth beans and 19-26 parts of herba taraxaci. The raw materials of the traditional Chinese medicine are convenient to obtain and low in cost, and soap production process is mature; the soap contains multiple traditions Chinese medicine components and can be directly applied to skin, chemical stimulus is avoided, effect of skin moisturizing and beautifying, nourishing and cleaning and bacteria killing is achieved, and after-flavor is retained after cleaning; the soap is especially suitable for youngsters after movement and has quite good efficacy in sweat removing, skin wakening and bacteria inhibiting.