31results about How to "Easy purity" patented technology

The invention relates to a high-purity sodium rabeprazole compound, belonging to the technical field of medicine. The method includes the following steps: dissolving crude sodium rabeprazole synthesized by the reaction of rabeprazole and sodium hydroxide in water, adjusting pH value to be faintly acid to neutral by using solid acid salt, and collecting precipitated solid; after dissolving the solid with organic solvent, conducting elution and purification by using eluting agent through macroporous adsorption resin, and collecting eluent; and adjusting the pH value of the eluent to be alkaline, and collecting the precipitated solid to obtain the pure sodium rabeprazole.

The recent invention provide an organic electroluminescence display device with color purity adjustment, particularly white purity increased, without increasing formation processes. For each of unit pixels formed on an insulating film INS formed on a principal surface of a glass substrate, a bank BNK is provided on a bottom electrode BEL being a pixel electrode. The bank BNK has the shape of a bank that surrounds a pixel concerned, for each of pixels, and an organic electroluminescence light emitting layer is charged within a region surrounded by the banks BNKs. Between the banks BNKs, a green light emitting layer (G light emitting layer), a blue light emitting layer (B light emitting layer), and a red light emitting layer (R light emitting layer) are provided. At the same time as the formation of these color light emitting layers, light emitting layers of three colors, the green light emitting layer (G light emitting layer), the blue light emitting layer (B light emitting layer), and the red light emitting layer (R light emitting layer) are stacked on a region of a white pixel to form a white light emitting layer (G+B+R). An upper electrode UEL is formed over the green light emitting layer (G light emitting layer), the blue light emitting layer (B light emitting layer), the red light emitting layer (R light emitting layer), and the white light emitting layer (G+B+R light emitting layer).

The object of the present invention is to provide a production method wherein synthesis of a cyclic organic silicon compound similar to oxa-silacyclopentanes is completed in a single-step reaction. It is also to provide an organic silicon resin having an alcoholic hydroxyl group, which is capable of easily controlling its construction and is longitudinally stable.

The means for solving is to produce the cyclic organic silicon compound represented by the formula (3) below by reacting an olefin represented by the formula (1) below and an alkoxysilane represented by the formula (2) below in the presence of a catalyst comprising a transition metal.

(In the formula, Z is alkenyl group having carbon atoms from 2 to 5 where the terminal carbon atom forms a C═C bond, R is methyl group or hydrogen atom, and Me is methyl group.)

(In the formula, R₁ is alkyl group or alkoxyl group, having carbon atoms from 1 to 3, and R₂ is alkyl group having carbon atoms from 1 to 3.)

(In the formula, Z′ is alkylene group having carbon atoms from 2 to 5.) And it is an organic silicon resin having an alcoholic hydroxyl group obtained by performing hydrolysis and condensation of a cyclic organic silicon compound represented by the formula (3) above, or of a mixture of this and a polyfunctional alkoxysilane.

The present invention relates to a preparation method of clofarabine, comprising mixture of 2-adenine chlorine and the compound of formula I. the reaction is done under mild conditions and an appropriate temperature; the basically pure compound of the formula III can be prepared after separation. The high-purity clofarabine can be got through hydrolysis under alkaline conditions.

The invention relates to a safe and reliable method for preparing lithium hexafluorophosphate by using a composite solvent. The technical steps of the method are simple. The method comprises steps that: anhydrous phosphoric acid, calcium fluoride and sulfur oxide are subject to a reaction, such that PF5 gas is obtained by evaporation; the evaporated PF5 gas is dehydrated, such that a high-purity anhydrous PF5 product is obtained; diethyl ether and anhydrous methyl cyanide are respectively dehydrated, such that high-purity diethyl ether and anhydrous methyl cyanide are obtained; high-purity lithium fluoride is added to the diethyl ether solution; methyl cyanide is added to the obtained solution; the PF5 gas is slowly delivered into the solution while stirring; when a reaction is finished, high-purity nitrogen is delivered into the solution, such that displacement is carried out until no PF5 gas is remained in a vessel; a dry product Li(CH3CN)4PF6 obtained through distillation is heatedand decomposed, such that LiPF6 is prepared; LiPF6 is dissolved under room temperature, such that a solution with a concentration of 1M is obtained; the solution is filtered by using a precise filterwith a specification of 0.2mum, such that a clarified solution is obtained; the solution is dried, such that a pure LiPF6 product is obtained.

The invention discloses a preparation method for dihydrostreptomycin sulphate and belongs to the production preparation technology of semi-synthesis antibiotics. The method comprises the following steps: treating with acid; performing ion exchange; adsorbing with large-pore amino resin; hydrogenating; performing secondary ion exchange; purifying by a mixed bed; treating with activated carbon; concentrating through a nanofiltration membrane; decolorizing by activated carbon; and treating with an ultrafiltration membrane and performing spray drying. According to the invention, the dosage of oxalic acid in a preparation process is reduced, the use ratio of the reducing agent is increased, the production cost is lowered, the production efficiency is increased, the method can meet the industrial production requirement and the product purity, quality yield and total recovery of the dihydrostreptomycin sulphate are increased.

The invention discloses a chemical synthesis method for triacetylganciclovir of a structural formula (I). The synthesis method comprises that: monoacetylguanine of a structural formula (II) and 1,3-dihalo-2-(acetoxylmethoxy) propane of a structural formula (III) are used raw materials to be reacted in a solvent A at 100 to 150 DEG C in the presence of a catalyst to form dihalo-2- acetyl- ganciclovir; the dihalo-2- acetyl- ganciclovir and an acetate are completely reacted in an organic solvent B at 70 to 150 DEG C; and the triacetylganciclovir is obtained after post treatment. The invention is reasonable in process, high in reaction yield, high in product purity and low in production cost and has good process application value.

The invention discloses a preparation method of p-aminophenylacetic acid. The method comprises the following steps: uniformly mixing water, iron chloride and p-aminophenylacetic acid, heating the materials to the temperature of 60-90 DEG C under nitrogen atmosphere, dropping a hydrazine hydrate aqueous solution, insulating for 1-2 hours, cooling the material for crystallization, filtering the material to take a filter cake, washing the filter cake, and drying the product to obtain p-aminophenylacetic acid. According to the method, a difficulty processed solid waste is not generated, an organic solvent is not required, the environment is protected, the reaction condition is mild, operation is simple, and the method is suitable for industrial production, yield is high, the purity of the prepared p-aminophenylacetic acid is good, and the method provides the help for normal and stable production for actarit.

The embodiment of the invention discloses a preparation method of ethyl 3-ethoxypropionate, and relates to the technical field of chemical industry synthesis. According to the scheme, low-acidity absolute ethyl alcohol and ethyl acrylate are subjected to an addition reaction under the catalytic action of a strongly basic ion exchange resin to prepare ethyl 3-ethoxypropionate, wherein the acidity of the reactant is within 10ppm and cannot affect the catalyst, so that the conversion rate of the catalyst is high so as to achieve high yield (the conversion rate and the yield of the scheme are morethan 98%). According to the invention, the method has the advantages of simplicity, mild conditions, few side reactions and easy regeneration of the catalyst; and the product easily achieves the purity of more than 99.8%, can be further processed into an electronic grade, can be used in photoelectric industry, greatly simplifies the separation process, and is convenient for continuous production.

In order to solve the problem that the crystallization mother liquor is difficult to treat in the adipic acid crystallization refining process in the prior art, the invention provides the treatment method of the crystallization mother liquor in the adipic acid crystallization refining process. The method can effectively remove other impurities in the mixture of adipic acid and glutaric acid in thecrystallization mother liquor. According to the technical schemes, the treatment method of the crystallization mother liquor in the adipic acid crystallization refining process comprises the following steps of: (1) mixing the crystallization mother liquor with an additive; (2) performing still standing and layering to obtain a light liquid phase 1 and a heavy liquid phase 2; (3) evaporating the light liquid phase 1 to obtain a material 3; and (4) crystallizing and separating the material 3 to obtain adipic acid and glutaric acid mixed crystals and mother liquor 4. According to the method, a solvent in the crystallization mother liquor is water or basically water, the additive comprises C1-C3 alcohol, and the weight ratio of the additive to the crystallization mother liquor is greater than0 and less than 0.3.