11results about How to "Efficient and stable" patented technology

The invention belongs to the technical field of chemistry, and particularly relates to a water-based stable transdermal preparation based on a structural nanoemulsion and a preparation method of the water-based stable transdermal preparation. 1% to 10% of a polyether block copolymer; 5%-20% of a co-emulsion; 0.1% to 15% of an active ingredient; and the balance of deionized water. Through a compounding system of an amino acid surfactant and a gemini surfactant and in combination with the synergistic effect of a specific polyether block copolymer, a nanoemulsion drug delivery system with a stable structure is constructed. Through a compound system of the amino acid surfactant and the gemini surfactant and by combining the synergistic effect of the polyether block copolymer, a nano-emulsion drug delivery system with a stable structure is constructed, and the nano-emulsion drug delivery system has good long-term storage stability and temperature adaptability, is not easy to layer and is uniform in particle size distribution.

The invention discloses a cooperative control method for manufacturing precision between complex thin-wall microsphere shell component forming processes, and relates to the technical field of microsphere shell component machining. The invention relates to a multi-process forming method for a micro-spherical crown structure on the surface of a complex thin-wall micro-spherical shell component in the prior art. According to an existing manufacturing precision keeping and reference transferring method, due to factors such as low soft and brittle hardness of a workpiece material, high precision requirement and multiple processes, the pose precision and the manufacturing precision of a micro-spherical shell are difficult to keep in multi-process circulation. The device is used for four workpiece circulation processes of material milling removal-laser etching marking-milling quality characterization-laser local modification-surface quality detection corresponding to three processes of milling removal of a micro spherical crown structure on the surface of a thin-wall micro spherical shell component, laser modification and measurement characterization. All the steps cooperate to achieve high-precision forming of the micro-spherical crown structure on the surface of the complex thin-wall micro-spherical shell component. The method is used for forming the complex thin-wall microsphere shell component.

The invention belongs to the technical field of biological medicine, and discloses an enteritis targeted probiotic delivery system and a preparation method and application thereof, the system comprises: i) a recombinant plasmid for coding an anti-inflammatory functional protein, the plasmid comprising an anti-inflammatory peptide fragment, a surface protein modification and an antibiotic switch; ii) Escherichia coli chassis bacteria which are subjected to genetic engineering modification and have the capability of high yield of outer membrane vesicles; and iii) introducing the recombinant plasmid into the escherichia coli chassis bacterium to obtain a recombinant engineering bacterium. The delivery system disclosed by the invention can target intestinal inflammation parts, deliver anti-inflammatory proteins through the outer membrane vesicles, and specifically release anti-inflammatory factors in an inflammation microenvironment, so that intestinal inflammation response is relieved; according to the present invention, the method can achieve the precise targeting on the intestinal inflammation, can effectively control the remote delivery and the continuous secretion of the anti-inflammatory protein in space and time, has advantages of strong targeting property, lasting effect, small side effect and the like, and provides the new strategy for the safe and efficient treatment of the intestinal inflammation diseases.

The embodiment of the invention discloses Chinese herbal medicine freckle-removing cream and a preparation method thereof. The Chinese herbal medicine freckle-removing cream is prepared from Chinese herbal medicine decoction liquor and a natural oil-in-water emulsion system, and the Chinese herbal medicine decoction liquor comprises the following medicinal materials: rehmannia, radix polygonati officinalis, Chinese waxgourd seed, stiff silkworm, caltrop, hawthorn, hairyvein agrimony, allium macrostemon, vine of multiflower knotweed, cortex albiziae, platycladi seed, lalang grass rhizome, perilla leaf, pepper and magnolia bark; the natural oil-in-water emulsifying system comprises the following raw materials: olive oil emulsifying wax, shea butter, jojoba oil, grape seed oil and vitamin E. Human body trials prove that the Chinese herbal medicine freckle-removing cream is fine and moist in skin feeling and not greasy after being smeared, and skin irritation reactions such as stabbing pain, redness and pruritus do not exist in the using process; after continuous use for 3 months, chloasma, sunburn and other color spots are obviously faded, the skin glossiness and fineness are obviously improved, and no obvious rebound occurs after the use is stopped; the composition is suitable for dry, oily, mixed and sensitive skin, and has good safety and tolerance.

The present application relates to a kind of refractory dispersant and its preparation method in the technical field of refractory additive, it is the comb structure copolymer, the copolymer includes styrene-maleic anhydride copolymer main chain, polyethylene glycol side chain grafted on the styrene-maleic anhydride copolymer main chain by ester bond, and phosphate radical;The polyethylene glycol side chain includes short-chain polyethylene glycol with molecular weight of 400-600 and long-chain polyethylene glycol with molecular weight of 800-1200.The present application realizes the precise division of function by using asymmetric compound polyethylene glycol side chain of specific molecular weight range, and controls esterification grafting degree is 50%-85%, not only can provide excellent initial wetting and dispersion force, ensure that slurry has excellent construction fluidity, but also can effectively prevent particle re-aggregation and sedimentation under static or shear, so as to fundamentally solve the technical problem that traditional dispersant is difficult to consider high initial fluidity and long-term anti-settling property, plasticity.

The utility model relates to the technical field of keyboard accessories, in particular to a balancing-rod-based keyboard satellite shaft capable of being automatically assembled in a matched mode, a mounting opening is formed in the side face of a shaft seat, the extending direction of the mounting opening is aligned with the horizontal direction of a mounting groove, and a sliding section is directly inserted into the mounting groove of the corresponding shaft center through the mounting opening. And the sliding section can horizontally slide in the mounting groove along with the vertical movement of the axle centers, so that the synchronous linkage of the axle centers at the two ends is realized. Through the horizontal alignment design of the shaft seat lateral mounting opening and the shaft center mounting groove, the linear insertion type assembly of the balance rod is realized, and the process requirements of an automatic production line can be met.

The utility model relates to the technical field of conductive parts, and particularly discloses a conductive part structure for fixedly connecting a silver strip, which comprises a base body and a second conductive body arranged on the base body, and the second conductive body is used for abutting against a conductive contact to form a conductive path; the base body is of a T-shaped plate-shaped structure and comprises a first plane part, a second plane part and an installation part, the installation part is used for installing the base body on an external structure, the extending direction of the first plane part and the extending direction of the second plane part are arranged in a crossed mode, and the first plane part is bent towards the direction where the installation part is located to form an arc-shaped part. According to the fixed connection silver strip conductive piece structure, the T-shaped base body design facilitates installation and fixation, and the first plane part and the second plane part are arranged in a crossed mode to facilitate space layout. Due to the arc-shaped part, the structural flexibility is enhanced, stress can be buffered, and damage caused by external force is reduced; the second conductor is matched with the conductive contact to form a conductive path, so that the conductive performance is guaranteed, and the product stability and reliability are improved.

This invention discloses a method for D2D communication, a remote user equipment (User Equipment), and a relay User Equipment (User Equipment). The method includes: the remote User Equipment receiving a D2D discovery message sent by the relay User Equipment and obtaining discontinuous reception parameters of the relay User Equipment; and sending a communication request message to the relay User Equipment based on the discontinuous reception parameters. Using this invention, the power consumption of the D2D link can be reduced.

The application relates to the technical field of metal powder processing, in particular to a high-efficiency production device for metal additive powder, which comprises a machine body, a discharge port is arranged at the bottom of the machine body, a roller is rotatably arranged in the machine body, stirring rods are uniformly distributed on the outer surface of the roller, a plurality of grooves are arranged on the surface of the roller, an arc-shaped baffle is arranged above the roller in the machine body, and an auxiliary cleaning mechanism and a telescopic cleaning mechanism are further arranged in the machine body and used for cleaning the outer surfaces of the stirring rods and the roller. The high-efficiency production device for metal additive powder is provided with the auxiliary cleaning mechanism and the telescopic cleaning mechanism, the elastic scraping plate of the scraping plate is used for realizing dynamic cleaning of the surfaces of the roller and the stirring rods, the elastic compensation of the spring one and the spring two is matched, the cleaning components are tightly attached to the working surface, the adhesion and accumulation of materials caused by high temperature are efficiently removed, and the continuous operation stability of the device is improved.

The utility model relates to an electric drive axle which is used for an electric truck, the electric drive axle is provided with a main drive motor, a speed reducer assembly and a differential mechanism assembly, the speed reducer assembly is provided with a first-level speed reduction level, a first-gear transmission mechanism, a second-gear transmission mechanism, a third-gear transmission mechanism, a first gear shifting mechanism and a second gear shifting mechanism, the first speed reduction stage is composed of a first speed reduction driving gear and a first speed reduction driven gear which are meshed with each other, the first speed reduction driving gear is fixedly supported on a motor shaft, and the first-gear transmission mechanism is composed of a planetary gear reducer, a first driving gear and a first driven gear. The second-gear transmission mechanism is composed of a planet carrier of the planetary gear reducer, a first driving gear and a first driven gear, and the third-gear transmission mechanism is composed of a second driving gear and a second driven gear, the torque of the main drive motor is transmitted to the differential mechanism assembly through the first-stage speed reduction stage and the first-gear transmission mechanism or the second-gear transmission mechanism or the third-gear transmission mechanism.

This invention discloses a parameterized-driven microsphere insulation and anti-settling structure and its monitoring method. The settlement structure of this invention includes an outer shell, a first anti-settling enclosure, a second anti-settling enclosure, a third anti-settling enclosure, an inner shell, and glass microsphere filling. The first, second, and third anti-settling enclosures are sequentially arranged inside the outer shell, and the inner shell is arranged inside the third anti-settling enclosure. The first, second, and third anti-settling enclosures are connected by bolts. The outer shell is connected to the first anti-settling enclosure, and the inner shell is connected to the third anti-settling enclosure. The gaps between the outer shell, the first, second, and third anti-settling enclosures, and the inner shell are filled with glass microspheres. This invention achieves synergistic effects of highly efficient anti-settling, ultra-low temperature stability, and vacuum maintenance capability in the pure glass microsphere insulation layer, and can be widely applied in the insulation structure of liquid hydrogen storage tanks.