The invention discloses a negative-ion water purification ceramic ball. The negative-ion water purification ceramic ball comprises, by weight, 55-76 parts of Gui mineral, 32-54 parts of elbaite, 28-49 parts of basalt, 11-17 parts of potassium feldspar, 9-17 parts of zeolite, 8-14 parts of germanite, 12-17 parts of kaolin, 6-11 parts of indianite, 14-20 parts of bryozoatum, 7-14 parts of shell powder, 17-22 parts of pebble, 12-19 parts of pearl powder, 30-35 parts of pi-mineral balls, 11-15 parts of tourmaline balls, 14-18 parts of selenium-rich mineralized balls, 4-7 parts of negative-potential balls, 65-90 parts of limonite balls, 38-47 parts of medical stone balls, 3-5 parts of activated carbon, 68-83 parts of tourmaline, 12-20 parts of far-infrared powder, 50-88 parts of clay, 13-22 parts of sepiolite, 40-60 parts of inorganic nano-selenium mineral powder, 40-58 parts of negative-potential mineral powder, 45-63 parts of adhesive, other 45-50 parts of kaolin and 20-40 parts of medical stone. The negative-ion water purification ceramic ball has the advantages that high-concentration efficient and durable negative ions can be released by the negative-ion water purification ceramic ball, electrolytic actions can be carried out between the negative-ion water purification ceramic ball and water, accordingly, hydroxide ions with negative electricity can be generated, macromolecule groups in the water can be diminished, and the dissolving capacity and the permeability of the water can be improved.