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31results about How to "Inhibits oxidase activity" patented technology
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Lactobacillus plantarum UA-416 strain and application thereof
ActiveCN108048368ALower serum uric acidInhibits oxidase activityBacteriaSkeletal disorderCreatinine riseTherapeutic effect
The invention discloses a lactobacillus plantarum UA-416 strain and application thereof, and belongs to the field of functional food microbes. Blanks of lactobacillus plantarum in the effects of lowering uric acid and resisting gout are filled up. According to the lactobacillus plantarum (Lactobacillus plantarum) UA-416 strain provided by the invention, the bacterial strain is already collected inthe China Center for Type Culture Collection (CCTCC) on July 25, 2017; the collection number is CCTCC NO: M2017419. The lactobacillus plantarum UA-416 strain provided by the invention can be used foreffectively lowering the level of blood uric acid, is used for improving the levels of urea nitrogen and creatinine and inhibiting the activity of xanthine oxidase in serum, and has prevention and treatment effects on uricemia or the gout.
Owner:JILIN MINGZHIYUAN BIOTECH
L.plantarum UA149 strain and application thereof
ActiveCN110055199AReduce synthesisLower uric acid levelsBacteriaMicroorganism based processesInflammatory factorsResearch Object
The invention discloses an L.plantarum UA149 strain and an application thereof, and belongs to the field of functional food microorganisms. The L.plantarum UA149 strain is deposited in China Typical Culture Collection Center on November 29, 2018 with the preservation number of CCTCC No: M2018842. The strain can be apply to preparing products with a uric acid reducing function or a gout resisting function. Lactic acid bacteria separated and identified from the surface of fleshy plant leaves are taken as research objects, and a new strain of lactic acid bacteria is screened through a large number of experiments. Hyperuricemia model rats are established by potassium oxazinate combined with fructose water, continuous intragastric administration of the lactobacillus plantarum UA149 strain for 14 days can significantly reduce the level of uric acid; and during gout attack, the release of inflammatory factors thromboxane and leukotriene mediated by neutrophils is reduced, the influx of neutrophils into joints is avoided, and the symptoms of redness, swelling, pain, heat and the like are reduced.
Owner:JILIN MINGZHIYUAN BIOTECH
Snapper breeding method
InactiveCN104839065AInhibits oxidase activityReduce generationClimate change adaptationAnimal feeding stuffLimoniumRedfish
The invention discloses a snapper breeding method. The snapper breeding method includes steps of 1) putting a net cage; 2) throwing fry into the net cage; 3) feeding submersible minced fillet, lemon and tea leaves when fry is smaller than 10 cm long; feeding fish and shrimp, lemon and tea leaves when fry is longer than or equal to 10 cm long; 4) separating fry once every twelve to eighteen days when fry is smaller than 10 cm long and once every fifteen to twenty five days and replacing the net cage with meshes of 15 to 20 mm when fry is 10 to 15 cm long and once every thirty to forty days and replacing the net cage with meshes of 20 to 25 mm when fry is longer than 15 cm. Lemon and tea leaves are fed in the feeding process, so as to effectively suppress lipoxidase activity and reduce aldehydes, and fishy smell of snappers is greatly reduced.
Owner:广西金海环岛渔业有限公司
Drug for treating purine metabolic disorder disease
ActiveCN103599123ARich sourcesLow priceOrganic active ingredientsSkeletal disorderDiseaseKidney stone
The invention relates to a drug for treating purine metabolic disorder disease, provides a flavonoids compound represented by the formula (I) and a modified derivative thereof, and a use in inhibition of xanthine oxidase activity and promotion of uric acid excretion function, wherein R1, R2 and R3 independently represent -H or monosaccharide residues, and R4 represents -H or -OH. In particular, the drug is used for treating purine metabolic disorder disease, and can be used for treating hyperuricemia and related diseases and reducing a individual serum UA level; the drug is used for treating hyperuricemia; the drug is used for treating the related diseases, such as for treating gouty arthritis and arthrophlogosis caused by hyperuricemia, and for treating chronic interstitial nephritis, kidney stones and the like caused by hyperuricemia. The drug has the advantages of natural chemical structure, safety, low toxicity, rapid curative effect and fewer side effects. (I).
Owner:广东世信药业有限公司
Method for brewing cherry fruit wine
ActiveCN101962609ASimple production processReduce astringencyMicroorganism based processesAlcoholic beverage preparationPectinaseVitamin C
The invention discloses a method for brewing cherry fruit wine. The method is characterized by comprising the following steps of: after selecting, washing and stoning cherries serving as raw materials, obtaining primary pulp by juicing; adding the following substances such as pectinase, calcium citrate, vitamin C, and g / L kojic acid into the primary pulp; standing for 5 to 24 hours; preparing clear juice by performing centrifugal separation; inoculating 0.05 to 2 percent of fruit wine yeast based on the weight of the clear juice; controlling a temperature and fermenting, wherein the primary fermentation temperature is between 16 and 28 DEG C, the fermentation time is 7 to 15 days, the secondary fermentation temperature is between 15 and 20 DEG C, and the fermentation time is 20 to 40 days; aging for 3 to 6 months; clarifying and filtering by adopting an ultra-filtration method; and filling, sterilizing and packaging to obtain finished cherry fruit wine. The method effectively improves a production process of cherry wine, reduces the content of polyphenol fundamentally, inhibits the activity of polyphenol oxidase, reduces harsh taste and improves stability. Compared with the prior art, the cherry fruit wine produced by the method maintains effective nutrient components, reduces the harsh taste and has a pure flavor.
Owner:SHANGHAI BACCHUS LIQUOR
Compound feed for crimson snappers
The invention discloses a compound feed for crimson snappers. The compound feed comprises a fish and shrimp feed, lemons and tea leaves, and the weight ratio of the fish shrimp feed to the lemons and the tea leaves is 100:0.5-1.5:3-5; preferably, the weight ratio of the fish shrimp feed to the lemons and the tea leaves is 100:1:4. A certain number of lemons and tea leaves are added to the compound feed disclosed by the invention on the basis of a conventional feed, so that the activity of lipoxygenase can be effectively inhibited, the generation of aldehydes materials is reduced, and the stink odor of the crimson snappers is largely reduced; because nutritional ingredients in the lemons and the tea leaves generate a certain attractant effect on the crimson snappers, the immunity of the crimson snappers is improved, and the feed coefficients and the survival rate are increased.
Owner:钦州市钦州港七十二泾渔业养殖专业合作社
Preparation method of radix ginseng health-care green tea
InactiveCN107372912AInhibits oxidase activityReduce lossPre-extraction tea treatmentRoll formingTraditional medicine
The invention discloses a preparation method of radix ginseng health-care green tea and belongs to the technical field of preparation methods of health-care tea. Radix ginseng leaves are directly soaked with water for drinking, are poor in mouth feel and have health-care efficacy, but are not beneficial to popularization. The preparation method comprises the following steps: picking up fresh leaves; mixing two kinds of leaves; mechanically cutting into strips; withering with hot air; carrying out microwave heating; carrying out cooling moisture retaining; adding enzyme and kneading; sieving; primarily drying with hot air; carrying out electromagnetic roll forming, electromagnetic strip finishing, electromagnetic winnowing and microwave sterilization; obtaining radix ginseng green tea. The preparation of the radix ginseng health-care green tea is realized, and efficient utilization of radix ginseng plants and tea resources is enhanced; the radix ginseng health-care green tea is good in color, aroma, taste, shape and quality and excellent in nutritional and health-care functions.
Owner:安徽九朵莲实业股份有限公司
Manufacturing technology of purple lycium barbarum leaf tea
The invention discloses a manufacturing technology of purple lycium barbarum leaf tea. The manufacturing technology comprises the steps of picking and cleaning purple lycium barbarum leaves, performing deactivation of enzymes for four times, rolling for molding and drying to realize formation. To be specific, the preliminary low-temperature deactivation of enzymes is executed, then middle-temperature water bath fumigation is executed, and finally, high-temperature frying is executed; the first three deactivation of enzymes is implemented from low temperature to high temperature, and the temperature is moderate and is always below 90 DEG C, so that the activity of oxidase of the purple lycium barbarum leaves is inhibited while other substances in the purple lycium barbarum leaves cannot be damaged; rapid cooling freezing is executed, so that the deactivation of enzymes is complete, furthermore, the nutritional components and trace elements in the lycium barbarum leaves can be retained in the leaves to the maximum extent, and in particular, the content of Zn in the purple lycium barbarum leaf tea is much higher than that of common green lycium barbarum leaf tea.
Owner:厦门恒春园农艺有限公司
Cereal powder dual-coated multi-preventive biological fresh keeping film and preparation method thereof
ActiveCN107509808AInsect-resistantWith biological antioxidantEdible seed preservationFlat articlesLow-density polyethyleneAdhesive
The invention relates to a cereal powder dual-coated multi-preventive biological fresh keeping film and a preparation method thereof. The inner layer of the film is composed of the following components in parts by weight: 80 to 100 parts of microencapsulated plant essential oil insect-proof mildew preventive, 5 to 10 parts of mildew-proof film forming agent, 2 to 5 parts of antioxidant, and 75 to 84 parts of dispersant. The middle support layer of the film is composed of the following components in parts by weight: 20 to 35 parts of low density polyethylene resin, 70 to 100 parts of low density linear polyethylene resin, and 1 to 3 parts of mildew preventive. The outer coating is composed of the following components in parts by weight: 10 to 15 parts of microencapsulation agent of garlicin and capsaicin, and 5 to 8 parts of adhesive. The inner layer and the outer coating are sprayed on the middle support layer to prepare the cereal powder dual-coated multi-preventive biological fresh keeping film. The biocontrol mechanism is utilized, biological source fresh keeping materials are used to prepare the dual-coated film with a mildew-proof function, the oxidation and slow release problems of the coating functional material are solved by a microencapsulation treatment; the activity of fatty acid oxidase is inhibited for a long time; and the film can prevent insects, mold, aging, and mice and can delay the rancidity of cereals.
Owner:天津市雅锋食品科技发展有限公司
Geniposide derivative with xanthine oxidase inhibitory activity as well as preparation method and application of geniposide derivative
ActiveCN114315929AInhibits xanthine oxidase activityInhibits oxidase activitySugar derivativesSkeletal disorderPurine-Xanthine OxidaseChemical compound
The invention belongs to the field of compound synthesis, and particularly relates to a geniposide derivative with xanthine oxidase inhibitory activity as well as a preparation method and application of the geniposide derivative. The geniposide derivative has a molecular structure shown in the specification. According to the invention, a novel geniposide derivative is synthesized, and the geniposide derivative has an obvious effect of inhibiting the activity of xanthine oxidase; the geniposide is subjected to structural modification, so that the biological activity of the geniposide can be greatly improved, and the geniposide has important practical significance on research and development of novel uric acid reducing drugs; according to the geniposide derivative with the xanthine oxidase inhibitory activity, related structural modification is carried out by taking geniposide as a raw material, the synthesis method is simple, the raw material price is low, and the structure is novel.
Owner:VEGETABLE RES INST OF SHANDONG ACADEMY OF AGRI SCI +1
Processing method capable of prolonging green tea shelf life
InactiveCN102370012APrevent aging and deteriorationExtended shelf lifePre-extraction tea treatmentVitamin CMathematical model
The invention discloses a processing method capable of prolonging a green tea shelf life, and belongs to the technical field of agricultural product storage and processing. The processing method comprises the following steps of 1, forecasting single layer moisture adsorption content of a processed green tea end product through a mathematical model according to a green tea isothermal adsorption curve, 2, carrying out microwave and far-infrared heating treatment on the processed green tea end product so that moisture activity of the processed green tea end product is controlled in a range of 0.2 to 0.4; and 3, packaging the processed green tea end product from the step 2 in a moisture-proof and light-proof environment, and storing the packaged green tea end product at normal temperature. The processing method adopts a microwave and far-infrared technology to carry out moisture activity control, thoroughly inhibits the activity of residual oxidase, minimizes chemical activities of green tea components, fundamentally inhibits various aging reactions in green tea storage, prevents oxidation of green tea active ingredients such as tea polyphenols, vitamin C and the like, maintains the most stable state of green tea, prevents green tea aging and deterioration in storage, and prolongs a green tea shelf life to the utmost extent.
Owner:JIANGNAN UNIV
Fructus gardeniae substitutional tea and method for organoleptic optimization of formula of fructus gardeniae substitutional tea
InactiveCN113383842AInhibits oxidase activityLower uric acidChemical property predictionOrganic active ingredientsBiotechnologyXanthine
The invention relates to the field of food, in particular to fructus gardeniae substitutional tea and a method for organoleptic optimization of a formula of the fructus gardeniae substitutional tea. The substitutional tea with specific proportioning components can effectively inhibit the activity of xanthine oxidase. The invention also provides a method for searching the organoleptic optimization of the formula of the fructus gardeniae substitutional tea. The optimal component ratio is finally obtained by establishing an optimization model and researching the influence of the components of the substitutional tea on the sense organs, and therefore, the sensory value of the substitutional tea is greatly improved while efficacy is ensured. According to the invention, development and utilization of cape jasmine resources are accelerated, a formula optimization thought is provided, economic development is driven, and ecological benefits and social benefits are improved.
Owner:CHONGQING ACAD OF CHINESE MATERIA MEDICA
1-N-ethyl-4-N-2'-substituted acylhydrazine-1H-pyrazol [3, 4-d] miazines derivative as well as preparation method and application thereof
InactiveCN102746309AGood antitumor activityGrowth inhibitionOrganic active ingredientsOrganic chemistryAcylhydrazineGout
The invention provides an allopurinol derivative shown in a formula I and a method for preparing the same. The allopurinol derivative can effectively inhibit tumor growth, and has a good antitumor effect; the allopurinol derivative can also effectively inhibit xanthine oxidase activity, can be used for gout treatment, and provides a new pharmaceutical option for clinically treating cancer and gout; and moreover, the preparation method of the compound is simple, is lower in cost, and has high yield and a good industrial application prospect.
![1-N-ethyl-4-N-2'-substituted acylhydrazine-1H-pyrazol [3, 4-d] miazines derivative as well as preparation method and application thereof](https://images-eureka.patsnap.com/patent_img/f302729f-4b86-4de0-92ca-462aa850092c/FDA00001865055400011.png "1-N-ethyl-4-N-2'-substituted acylhydrazine-1H-pyrazol [3, 4-d] miazines derivative as well as preparation method and application thereof")
![1-N-ethyl-4-N-2'-substituted acylhydrazine-1H-pyrazol [3, 4-d] miazines derivative as well as preparation method and application thereof](https://images-eureka.patsnap.com/patent_img/f302729f-4b86-4de0-92ca-462aa850092c/BDA00001865055500011.png "1-N-ethyl-4-N-2'-substituted acylhydrazine-1H-pyrazol [3, 4-d] miazines derivative as well as preparation method and application thereof")
![1-N-ethyl-4-N-2'-substituted acylhydrazine-1H-pyrazol [3, 4-d] miazines derivative as well as preparation method and application thereof](https://images-eureka.patsnap.com/patent_img/f302729f-4b86-4de0-92ca-462aa850092c/BDA00001865055500012.png "1-N-ethyl-4-N-2'-substituted acylhydrazine-1H-pyrazol [3, 4-d] miazines derivative as well as preparation method and application thereof")
Owner:SICHUAN UNIV
High-viscosity masking paper tape and preparation process thereof
InactiveCN106752977AFast dryingWith thickeningNon-macromolecular adhesive additivesOrganic non-macromolecular adhesiveAntioxidantPaper tape
The invention relates to a tape and a preparation process thereof, in particular to a high-viscosity masking paper tape and a preparation process thereof. The invention provides the high-viscosity masking paper tape with the advantages of no toxicity, no harm, high viscosity and good use performance, and the preparation process thereof. A high-viscosity masking paper tape glue formula comprises the following raw materials in parts by weight: 60 to 80 parts of main body rubber, 2 to 4 parts of antioxidants, 3 to 5 parts of rosin ester, 4 to 6 parts of emulsifiers, 7 to 9 parts of acrylic acid, 1 to 3 parts of sodium polyacrylate, 25 to 30 parts of propylene butyrate and 1.5 to 2.5 parts of degassing agents; the preparation process comprises five steps. The prepared high-viscosity masking paper tape has high viscosity and can be used in life and industry; the condition that the falling phenomenon occurs within a short time is avoided; ageing resistance, water resistance and solvent resistance are realized; the isolation performance of base paper is improved.
Owner:嘉善弘欣化工厂(普通合伙)
Feed for artificial culturing of leiocassis longirostris
InactiveCN107252009AImprove survival rateImprove economic efficiencyClimate change adaptationAnimal feeding stuffDandelionHerb
The invention discloses a feed for artificial culturing of leiocassis longirostris. Raw materials of the feed comprise, in parts by weight, 18-26 parts of millet, 5-10 parts of cicada pupa powder, 2-8 parts of kelp powder, 1-5 parts of mulberry leaf powder, 30-40 parts of an adhesive, 1-5 parts of baikal skullcap roots, 1-2 parts of dandelion herbs, 1-2 parts of immature flower of Japanese honeysuckle, 0.5-1.2 parts of coptis roots, 0.15-0.35 part of EM bacteria, 0.2-0.6 part of lecithin, 0.1-0.3 part of beta-carotene, and 0.5-1 part of a phagostimulant. The feed for artificial culturing of the leiocassis longirostris provided by the invention can obviously raise the surviving rate of the leiocassis longirostris, improve economic benefits of the artificial culturing, and significantly decrease the generation of bacterium infection and diseases such as fatty liver in a culturing process. The feed improves the quality of the leiocassis longirostris, and contains no antibiotic.
Owner:全椒县鮰鱼养殖专业合作社
Unattended breeding sewage treatment system
PendingCN111268852ASimple process flowReduce construction costsWater treatment parameter controlSpecific water treatment objectivesPig farmsWater discharge
The invention relates to the field of pig farm sewage treatment. The invention particularly relates to an unattended breeding sewage treatment system. The system comprises an adjusting tank, a coagulating sedimentation tank, a UASB reactor, a primary denitrification reaction tank, a primary nitrification reaction tank, a primary sedimentation tank, a short-cut nitrification-denitrification device,a secondary sedimentation tank and a water discharge tank which are sequentially connected through a water conveying pipeline, and also comprises a PLC system used for controlling the sewage treatment process, a gas conveying pipeline used for conveying gas, and a sludge conveying pipeline used for conveying sludge. An artificial intelligence management mode is adopted, the intelligent level is high, the automation degree is high, the sewage treatment efficiency is high, the treatment effect is good, and energy conservation and environmental protection are facilitated.
Owner:武汉鸿鑫天环保工程有限公司
A strain of Lactobacillus plantarum ua149 and its application
ActiveCN110055199BLower blood uric acid levelsReduce synthesisBacteriaSkeletal disorderBiotechnologyInflammatory factors
Owner:JILIN MINGZHIYUAN BIOTECH
A drug for treating purine metabolic disorders
ActiveCN103599123BRich sourcesLow priceOrganic active ingredientsSkeletal disorderDiseaseKidney stone
Owner:广东世信药业有限公司
Glue firm in adhesion and preparation technology thereof
InactiveCN106519996AGood adhesionWeak tear-repellentNon-macromolecular adhesive additivesOrganic non-macromolecular adhesiveWater vaporAntioxidant
The invention relates to glue and a preparation technology thereof, in particular to glue firm in adhesion and a preparation technology thereof. The glue is high in adhesion firmness, high in chemical corrosion resistance and water vapor erosion resistance, little in viscosity change after long-time storage and not prone to spoilage. The glue firm in adhesion is prepared from, by weight, 50-55 parts of ethyl cyanoacrylate monomers, 3-5 parts of acrylamide, 2-4 parts of emulsifier, 5-8 parts of ethyl cyanoacrylate and the like. The preparation technology includes five steps. The glue formed by mixing and reacting ethyl cyanoacrylate monomers, acrylamide, emulsifier, ethyl cyanoacrylate, an antioxidant, abietin and the like is little in viscosity change after long-time storage, free of offensive odor and toxin, harmless to bodies and capable of being used in life and industries, articles need to be attached to firm places, are not likely to fall off, can be maintained for a long time and is fixedly pasted.
Owner:嘉善弘欣化工厂(普通合伙)
Method for brewing cherry fruit wine
ActiveCN101962609BSimple production processReduce astringencyAlcoholic beverage preparationMicroorganism based processesPectinaseVitamin C
The invention discloses a method for brewing cherry fruit wine. The method is characterized by comprising the following steps of: after selecting, washing and stoning cherries serving as raw materials, obtaining primary pulp by juicing; adding the following substances such as pectinase, calcium citrate, vitamin C, and g / L kojic acid into the primary pulp; standing for 5 to 24 hours; preparing clear juice by performing centrifugal separation; inoculating 0.05 to 2 percent of fruit wine yeast based on the weight of the clear juice; controlling a temperature and fermenting, wherein the primary fermentation temperature is between 16 and 28 DEG C, the fermentation time is 7 to 15 days, the secondary fermentation temperature is between 15 and 20 DEG C, and the fermentation time is 20 to 40 days; aging for 3 to 6 months; clarifying and filtering by adopting an ultra-filtration method; and filling, sterilizing and packaging to obtain finished cherry fruit wine. The method effectively improvesa production process of cherry wine, reduces the content of polyphenol fundamentally, inhibits the activity of polyphenol oxidase, reduces harsh taste and improves stability. Compared with the prior art, the cherry fruit wine produced by the method maintains effective nutrient components, reduces the harsh taste and has a pure flavor.
Owner:SHANGHAI BACCHUS LIQUOR
Application of vitisinol D in the preparation of xanthine oxidase inhibitory drugs
ActiveCN113304138BStrong xanthine oxidase inhibitionGood xanthine oxidase inhibitory activityMetabolism disorderSkeletal disorderPurine-Xanthine OxidaseXanthine
The invention belongs to the technical field of the application of active ingredients of Chinese medicinal materials, and in particular relates to the application of Vitisinol D in the preparation of xanthine oxidase inhibitory drugs. The xanthine oxidase inhibitory drugs are composed of Vitisinol D as an active ingredient and other pharmaceutical excipients or carrier, the molecular formula of the Vitisinol D is C 28 h 22 o 6 , Vitisinol D of the present invention is a monomer compound isolated from gorse root, which has high safety and strong xanthine oxidase inhibitory effect.
Owner:GUIZHOU MEDICAL UNIV
A strain of Lactobacillus plantarum ua-416 and its application
ActiveCN108048368BImprove the level ofInhibits oxidase activityBacteriaSkeletal disorderSerum igeUrea nitrogen
Owner:JILIN MINGZHIYUAN BIOTECH
1-N-benzyl allopurinol derivative as well as preparation method and application thereof
InactiveCN102746307BGood anti-tumor effectGrowth inhibitionOrganic active ingredientsOrganic chemistryUse medicationBenzyl group
The invention provides an allopurinol derivative shown in a formula I, as well as a preparation method and an application thereof. The allopurinol derivative can effectively inhibit tumor growth, and has a good antitumor effect; the allopurinol derivative can also effectively inhibit xanthine oxidase activity, can be used for gout treatment, and provides a new pharmaceutical option for clinicallytreating cancer and gout; and moreover, the preparation method of the compound is simple, is lower in cost, and has high yield and a good industrial application prospect.
Owner:SICHUAN UNIV
Application of herba lycopi flavone in preparation of medicine for resisting hyperuricemia and gout
PendingCN114377005AInhibits oxidase activityOrganic active ingredientsSkeletal disorderDiseasePeroxidase
The invention belongs to the technical field of medicines, and discloses application of herba lycopi flavone in preparation of anti-hyperuricemia and / or anti-gout medicines, hyperuricemia comprises primary and secondary hyperuricemia, and the concentration of uric acid in blood caused by various factors is higher than 420 [mu] mol / L for men and 357 [mu] mol / L for women (measured by a phosphotungstic acid reduction method). Or determining adult gout higher than 420 mu mol / L by a uricase-peroxidase coupling method, wherein the gout comprises primary gout and secondary gout. It is found that the herba lycopi flavone can significantly reduce the activity of xanthine oxidase in vitro and can effectively reduce the serum uric acid level of a hyperuricemia model mouse at the same time, and it is indicated that the herba lycopi flavone can be used for preparing the anti-hyperuricemia and / or anti-gout medicine. The invention provides a safe, effective and economical active substance for preparing medicines for preventing and / or treating hyperuricemia or / and gout diseases.
Owner:INST OF MATERIA MEDICA AN INST OF THE CHINESE ACAD OF MEDICAL SCI
Allopurinol derivative and preparation method and application thereof
InactiveCN102746308BImprove anti-tumor effectGrowth inhibitionOrganic active ingredientsOrganic chemistryUse medicationAntitumor activity
The invention provides an allopurinol derivative as shown in Formula I, and a preparation method and application thereof. Tumor growth can be effectively suppressed by the allopurinol derivative provided by the invention, and the allopurinol derivative has good antitumor activity. The activity of xanthine oxidase can be effectively suppressed by the allopurinol derivative, and the allopurinol derivative can be used for treating gout and provides a new drug choice for treating cancer and gout. Additionally, the preparation method of the compound provided by the invention has the advantages of simplicity, lower cost, high yield and good industrial application prospect.
Owner:SICHUAN UNIV
Live vaccine, live vaccine freeze-dried powder, live vaccine protective agent as well as preparation method and application thereof
PendingCN111700865AAvoid sex changePrevent oxidative deteriorationAntibacterial agentsPowder deliveryBiotechnologySodium ascorbate
The invention belongs to the technical field of live vaccine protective agents, and particularly relates to a live vaccine, a live vaccine freeze-dried powder, a live vaccine protective agent as wellas a preparation method and application thereof. The live vaccine protective agent comprises water-soluble gelatin, oligosaccharides, sorbitol, polyvinylpyrrolidone, sodium ascorbate, sodium L-glutamate, a 199 culture medium and water for injection. The live vaccine protectant provided by the invention can increase the survival rate and shelf life of bacteria, and the protective function of the live vaccine protective agent on bacteria under a high temperature condition can be improved; and the situation of animal allergies and immune failure caused by improper storage of the live vaccine canbe also avoided.
Owner:GANSU ANIMAL HUSBANDRY & VETERINARY MEDICINE INST
Feed for improving leiocassis longirostris flavor
InactiveCN107183338AImprove survival rateImprove qualityClimate change adaptationAnimal feeding stuffOxygenase activityFood flavor
The invention discloses a feed for improving leiocassis longirostris flavor, which is prepared from, by weight, 4-8 parts of guar gum sodium carboxymethylcellulose composite, 40-50 parts of high gluten flour, 16-20 parts of maltose, 4-8 parts of bacteriostat system, 1-3 parts of hawthorn, 2-4 parts of Amomum tsao-ko, 30-50 parts of germinated brown rice powder, 16-22 parts of earthworm powder, 10-16 parts of seaweed meal, 4-8 parts of pine needle meal, and 3-3.6 parts of intestinal tract promoter. The feed has advantages of improving immunity and survival rate of leiocassis longirostris, obviously improving the survival rate, increasing economic benefit of artificial cultivation, effectively inhibiting lipoxidase activity, reducing generation of aldehydes material, and greatly decreasing stink odor of leiocassis longirostris; meanwhile, the leiocassis longirostris excrement is few and water body is not polluted.
Owner:全椒县鮰鱼养殖专业合作社
1-N-ethyl-4-N-2'-substituted acylhydrazine-1H-pyrazol [3, 4-d] miazines derivative as well as preparation method and application thereof
InactiveCN102746309BGood antitumor activityGrowth inhibitionOrganic active ingredientsOrganic chemistryUse medicationAcylhydrazine
![1-N-ethyl-4-N-2'-substituted acylhydrazine-1H-pyrazol [3, 4-d] miazines derivative as well as preparation method and application thereof](https://images-eureka.patsnap.com/patent_img/813b1da1-39bf-4666-b5ad-7cc563febd85/BDA00001865055500011.PNG "1-N-ethyl-4-N-2'-substituted acylhydrazine-1H-pyrazol [3, 4-d] miazines derivative as well as preparation method and application thereof")
![1-N-ethyl-4-N-2'-substituted acylhydrazine-1H-pyrazol [3, 4-d] miazines derivative as well as preparation method and application thereof](https://images-eureka.patsnap.com/patent_img/813b1da1-39bf-4666-b5ad-7cc563febd85/BDA00001865055500012.PNG "1-N-ethyl-4-N-2'-substituted acylhydrazine-1H-pyrazol [3, 4-d] miazines derivative as well as preparation method and application thereof")
![1-N-ethyl-4-N-2'-substituted acylhydrazine-1H-pyrazol [3, 4-d] miazines derivative as well as preparation method and application thereof](https://images-eureka.patsnap.com/patent_img/813b1da1-39bf-4666-b5ad-7cc563febd85/BDA00001865055500031.PNG "1-N-ethyl-4-N-2'-substituted acylhydrazine-1H-pyrazol [3, 4-d] miazines derivative as well as preparation method and application thereof")
Owner:SICHUAN UNIV
Five-grain powder two-way coating multi-proof biological preservative film and preparation method thereof
ActiveCN107509808BInsect-resistantWith biological antioxidantEdible seed preservationFlat articlesBiotechnologyLow-density polyethylene
Owner:天津市雅锋食品科技发展有限公司
A kind of Lactobacillus fermentum for preventing and treating hyperuricemia and its composition and application
ActiveCN113999805BGood bile salt toleranceImprove degradation rateAntibacterial agentsBacteriaBiotechnologyMetabolite
A lactobacillus fermentum for preventing and treating hyperuricemia, its composition and application, the lactobacillus fermentum GF1800 for preventing and treating hyperuricemia, deposit number: CCTCC NO: M 2021984. Lactobacillus fermentum GF1800 has high biological activity and strong acid production ability, can effectively inhibit the activity of pathogenic microorganisms and xanthine oxidase, can tolerate gastric acid and bile salts, and has significant effects on nucleosides, uric acid, cholesterol, nitrite, etc. It can effectively inhibit the intake of exogenous uric acid and the increase of endogenous uric acid, can significantly reduce the blood uric acid level of hyperuricemia, and at the same time improve the intestinal and kidney structural damage and inflammatory response. The invention also discloses a composition containing Lactobacillus fermentum GF1800 and its strain metabolites and postbiotics. Lactobacillus fermentum GF1800 and its postbiotics are used in the preparation and prevention of hyperuricemia or / and gout, degrading nucleosides, and inhibiting xanthine oxidation. Enzymes, lowering cholesterol, degrading nitrite, inhibiting the application of functional food or medicine of pathogenic bacteria.
Owner:SICHUAN GAOFUJI BIOLOGICAL TECH
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