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33results about How to "Produce synergy" patented technology

Polymer loaded with penicillin and nitric oxide at same time as well as preparation method and application of polymer

The invention belongs to the field of biomedical engineering and discloses a polymer loaded with penicillin and nitric oxide at the same time as well as a preparation method and application of the polymer. The structural formula of the polymer is described in the following description. For the polymer, a dendritic cation alkynyl group-contained polyamide-amine dendritic molecule PAMAM (polyamide-amine) as an NO donor, and a dendritic structure and a great quantity of secondary amine in the structure are beneficial to efficient loading of NO; in addition, PAMAM contains a great quantity of primary amine groups at the same time, so that efficient loading of the penicillin is facilitated, and efficient loading of NO and PCN is realized; polyamide-amine is grafted with chitosan, so that the biocompatibility of a material can be greatly improved, and meanwhile, high grafting ratio of a chitosan long chain to the polyamide-amine greatly increases the loading amounts of NO and PCN; and meanwhile, the antibacterial effect of the polymer loading the penicillin and NO at the same time is better than the antibacterial effect of a polymer singly loading the penicillin or NO, and the synergistic effect is generated. (The formula is shown in the description.).
Owner:JINAN UNIVERSITY

Traditional Chinese medicine immersing powder for treating foot sprain and contusion and preparation method thereof

ActiveCN107737312AAnti-inflammatory for jointsSmall toxicityPowder deliveryAntipyreticSide effectBalsam
The invention relates to the technical field of traditional Chinese medicine, and particularly relates to traditional Chinese medicine immersing powder for treating foot sprain and contusion and a preparation method thereof, solving the technical problems of great side effect, slow curative effect, and incapability of completely covering the focus of existing medicines for treating sprain and contusion. The traditional Chinese medicine immersing powder contains the following materials in parts by weight: 5-16 parts of cassia twig, 8-15 parts of mulberry twig, 3-9 parts of garden balsam stem, 5-9 parts of Antongteng, 8-15 parts of willow branch, 5-9 parts of rheum officinale, 5-9 parts of dandelion, 3-9 parts of turmeric, 5-9 parts of safflower carthamus, 5-9 parts of golden cypress, 5-9 parts of rhizoma drynariae, 5-9 parts of astragalus membranaceus, 3-6 parts of humulus scandens, 3-6 parts of coptis chinensis, 8-15 parts of Caulis Spatholobi, 3-6 parts of herba ephedra, and 5-9 partsof cacumen biotae. According to the traditional Chinese medicine immersing powder, when the traditional Chinese medicines are used, by interaction among medicines, the efficacy is enhanced, a synergistic effect is generated, the developing direction of multi-functional single traditional Chinese medicine is controlled, the therapeutic range is enlarged, the state of illness can be adapted, the toxic or side effect of medicine can be reduced, and the medicine property is relieved.
Owner:华震
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