The invention relates to an iron ore sintering device and method with coke replaced with biomass charcoal based on fuel layering and flue gas circulating, and belongs to the technical field of the iron and steel industry. The iron ore sintering device with the coke replaced with the biomass charcoal based on fuel layering and flue gas circulating comprises a sintering machine body, a mixing tank,an ignition furnace, a holding furnace, air bellows, a mixed flue gas circulating pipeline, a mixed flue gas circulating fan, a mixed flue gas dust removal device, a sintered ore cooling waste gas pipeline, a circulating flue gas pipeline, a sintering trolley, a large flue, a large flue dust removal desulfurizer, a large flue fan, a chimney and a sintering furnace. By means of the device and method, the biomass charcoal is adopted for replacing the coke, and reduction of fossil fuel consumption, utilization of flue gas waste heat, enrichment of SO2 in flue gas and reduction of the flue gas discharge amount can be achieved.