The invention relates to an amplitude modulation type radial polarization illumination confocal microimaging method and device. The device comprises a laser, a collimation and beam expansion system, apolarization state conversion system, an amplitude type spatial light modulator, a first beam splitter, a scanning galvanometer system, a high-numerical-value aperture objective lens, a sample, a white light source, a three-dimensional displacement table, a second beam splitter, a CCD camera, a cylinder lens, a size-variable confocal pinhole and a photomultiplier. Apodization of the sidelobe is performed by changing the size of the confocal pinhole to solve a problem of a large sidelobe; and the pinhole size is optimized according to the actual focusing spot size, so that noise is suppressed.With the method, the confocal microscopic imaging resolution can be effectively improved. Moreover, the system structure is simple, and no binary optical device needs to be introduced.