96 results about "9H-carbazole" patented technology

A novel cost effective process for the synthesis of phosphate salts of 1-(9H-carbazol-4yloxy)-3-[[2-(2-methoxyphenoxy)ethyl]amino]-propan-2-ol, (carvedilol phosphate) of formula (II) with high yields and purity is disclosed. More particularly, the invention discloses a process for preparation of crystalline phosphate salts of carvedilol using various phosphate forming reagents such as phosphorous pentoxide, polyphosphoric acid, dipotassium hydrogen phosphate, ammonium dihydrogen ortho phosphate, and sodium dihydrogen ortho phosphate in solvents selected from Acetonitrile, acetone and tetrahydrofuran. The solvents used to prepare solvates of carvedilol dihydrogen phosphate are methanol, ethanol and isopropyl alcohol.

The invention discloses a micro-porous metal organic framework material for methane and acetylene adsorption and storage, and a preparation method of the micro-porous metal organic framework material. The metal organic framework material is a three-dimensional crystal material prepared from self-assembling transition-metal ions and a polycarboxylic acid organic ligand 5,5',5''-(9H-carbazole-3,6,9-tri-yl)-m-phthalic acid by virtue of coordinate bonds. The metal organic framework material has the relatively large specific surface area and pore volume, the specific surface area can be 1200-1400m<2> / g, the pore volume is 0.6-0.8cm<3> / g, and the metal organic framework material is high in thermal stability and simple in preparation process. The material has high-density open metal sites, can increase the methane and acetylene adsorption and storage amount under 273K and 298K and can be expected to serve as a novel high-efficiency methane and acetylene adsorption and storage material.

The present invention relates to 3-(heteroaryl-amino)-1,2,3,4-tetrahydro-9H-carbazole derivatives of the formula (I),wherein R1, R2 and R3 are as described in the description and their use as prostaglandin receptor modulators, most particularly as prostaglandin D2 receptor modulators, in the treatment of various prostaglandin-mediated diseases and disorders, to pharmaceutical compositions containing these compounds and to processes for their preparation.

The invention discloses a phosphine-oxygen red / orange thermally activated delayed fluoresce material as well as a synthesis method and application thereof, relates to the thermally activated delayed fluoresce material as well as the synthesis method and the application thereof, and aims to solve the problems that a conventional red / orange TADF (Thermally Activated Delayed Fluoresce) material is slightly low in concentration quenching and electroluminescent device efficiency and rapid in attenuation because of high molecular polarity. The structural formula of the material is as shown in the specification. The synthesis method comprises the following steps: preparing 9-(2-bromine-4-(1,3-dioxolane-2-yl) phenyl-9H-carbazole or 9-(2-bromine-4-(1,3-dioxolane-2-yl) phenyl)-3,6-ditert-butyl-9H-carbazole, preparing 4-(9H-carbazole-9-yl)-3-(diphenylphosphine oxide) benzaldehyde or 4-(3,6-ditert-butyl-9H-carbazole-9-yl)-3-(diphenylphosphine oxide) benzaldehyde, and preparing a final product. By adopting the material disclosed by the invention, the efficiency of an electroluminescent device is remarkably improved, the quenching effect is reduced, and the efficiency stability of the electroluminescent device is improved. The material belongs to the field of fluorescence material preparation.

To provide a method for producing a wide variety of carbazole derivatives which have a simple and uncomplicated process and in which variations in the yield, purity, etc. of a desired substance which are caused by an aryl group introduced is reduced as much as possible. A method for producing a carbazole derivative represented by General Formula (1) is provided, in which 9-[4-(10-phenyl-9-anthryl)phenyl]-9H-carbazole having an active site at the 3-position of the carbazole skeleton and an aromatic compound having an active site are coupled.In the formula, Ar1 represents an aryl group with 6 to 13 carbon atoms in a ring, and Ar1 may have a substituent.

The present invention relates to (3-amino-1,2,3,4-tetrahydro-9H-carbazol-9-yl)-acetic acid derivatives of Formula (I) wherein R1, R2, R3, R4, R5 and R6 are as described in the description and their use as prostaglandin receptor modulators, most particularly as prostaglandin D2 receptor modulators, in the treatment of various prostaglandin-mediated diseases and disorders, to pharmaceutical compositions containing these compounds and to processes for their preparation.

The present invention relates to 3-(heteroaryl-amino)-1,2,3,4-tetrahydro-9H-carbazole derivatives of the formula (I),wherein R1, R2 and R3 are as described in the description and their use as prostaglandin receptor modulators, most particularly as prostaglandin D2 receptor modulators, in the treatment of various prostaglandin-mediated diseases and disorders, to pharmaceutical compositions containing these compounds and to processes for their preparation.

The invention relates to the field of organic photomultiplier detectors, an organic photomultiplier detector based on surface plasmon polariton uses an indium tin oxide ITO as an anode layer and poly(3, 4-ethylenedioxythiophene)-polystyrene sulfonic acid (PEDOT: PSS) as an anode layer, and uses any one of 3-hexylthiophene P3HT, poly[[9-(1-octylnonyl)-9H-carbazole-2, 7-dibasic]-2, 5-thiophene diyl-2, 1, 3-benzothiadiazole-4, 7-dibasic-2, 5-thienyl diyl (PCDTBT, PSBTBT: PC71BM] as a donor material of an organic active layer, and uses fullerene derivative PCBM as an acceptor material of the organic active layer, the donor material and the acceptor material constitute the organic active layer, and an integrated metal nano-grating matrix and a metal thin film are used as a cathode layer, and the nano-grating matrix is inlaid in the organic active layer.

The invention belongs to the technical field of analytical chemistry, and in particular relates to a carbazole-contained benzimidazole-substituted quinoline derivative, a preparation method and an application thereof. The carbazole-contained benzimidazole-substituted quinoline derivative is 3-(2-(8-(1H-benzo[d] imidazole-2-yl) quinoline-2-yl) ethenyl)-9-benzyl-9H-carbazole. The preparation method includes the steps of placing 2-methyl-8-(1H-benzimidazole) quinoline and 9-benzyl-9H-carbazole-3-formaldehyde into polar solvents, adding catalysts, stirring and performing backflow reaction; performing purification after the backflow reaction to obtain a target compound carbazole and benzimidazole-substituted quinoline derivative L. A benzimidazole quinoline derivative zinc ion fluorescent probe is excellent in complexing action with zinc ions and rapid in response, the response time of the Zn<2+>fluorescent probe for Zn<2+> is 50s, the lowest detection limit is 6.69*10-8mol / L, and the fluorescent probe can be used for quantitative trace detection of the zinc ions by fluorescence spectrophotometry.

The invention provides a novel carbazole fluorescent thiol marking reagent as well as a synthesis method and application thereof. The florescent marking reagent adopts carbazole as a fluorescent basering and activated C=C double bonds as reaction activity groups, is simple and convenient in synthesis step, easy to operate and can be synthesized in a large scale through two steps of reactions as follows: (1) enabling carbazole to react with 4-bromobenzaldehyde so as to obtain an intermediate (4-(9H-carbazole-9-yl) benzaldehyde; (2) enabling the intermediate (4-(9H-carbazole-9-yl) benzaldehydeto react with malononitrile so as to obtain a target product (4-(9H-carbazole-9-yl) benzaldehyde malononitrile, and performing recrystallization for three times with acetonitrile, thereby obtaining ayellow needle-shaped crystal. The chemical purity of the fluorescent marking reagent provided by the invention is up to 99%, and the fluorescent marking reagent is stable in chemical property. The novel carbazole fluorescent thiol marking reagent provided by the invention is capable of rapidly and accurately marking degradation thiol products of organic thiol ester insecticides under a gentle condition, and quantitative analysis on contents of organic thiol ester insecticides in reagent samples can be achieved.

The invention provides a fluorescent probe DCCO and a preparation method and application thereof. The fluorescent probe is 7-(diethylamino)-3-(E)-3-(9-ethyl-9H-carbazole-3-base)acryloyl-2H-pyran-2-ketone. The preparation method of the fluorescent probe DCCO comprises the steps that 3-acetyl-7-(diethylamino)-2H-pyran-2-ketone and 9-ethyl-9H-carbazole-3-formaldehyde amine are dissolved in an ethyl alcohol / acetonitrile (1 / 1, V / V) mixed solution in an equimolar ratio, piperidine is dripped, heating reflux is carried out, and the solution is changed from saffron yellow to red; decompression is carried out to remove a solvent, column chromatography isolation is carried out through a gradient elution method, and a crude product of the fluorescent probe is obtained; the crude product of the fluorescent probe is dissolved, filtered and dried to obtain a pure product. The detection of ClO<-> by the fluorescent probe is of a ratio type, the high sensitivity and good selectivity and stability are shown, and the fluorescent probe has the advantages that the detection process is simple, convenient and rapid, and detection results are accurate. The fluorescent probe DCCO can be applied in the detection of ClO<-> of biological samples.