Patents
Literature
Hiro is an intelligent assistant for R&D personnel, combined with Patent DNA, to facilitate innovative research.
Hiro

75 results about "Drug allergy" patented technology

An immune mediated adverse reaction to a drug.

Quantitative determination and drug allergy determination kits for helicobacter pylori viable bacteria and determination method

InactiveCN103757088ASolve the deficiency of only qualitative detection of Helicobacter pyloriSimple methodMicrobiological testing/measurementUrocaninaseDrug allergy
The invention discloses quantitative determination and drug allergy determination kits for helicobacter pylori viable bacteria and a determination method. The method adopts viable helicobacter pylori as a sample to be detected; the property that the viable helicobacter pylori can generate urease is used for rapidly and accurately reading the quantity of the helicobacter pylori by a helicobacter pylori colony counting standard method (CFU / ml, namely the bacterium individual quantity in each ml of bacterium liquid and a colony quantity standard curve); the detection result is accurate and sensitive and has high reliability; the counting difficulty of existing helicobacter pylori clinic microbiological identification, caused by difficult culture and complicated operation, is solved; the drug allergy determination kit and a preparation method, which are expanded by the invention, can be used for carrying out various drug allergy tests at the same time; clinicians can rapidly and conveniently screen suitable anti-helicobacter pylori medicines so that the time and the labor are saved and the cost is saved, so as to provide a beneficial technical solution for clinical scientific treatment.
Owner:SICHUAN VACCINE TECH

System for visually identifying and analyzing as well as identifying drug allergy and drug allergy detecting method

ActiveCN104749180ACompact structureRealize intelligent drug susceptibility identificationMaterial analysis by optical meansFiltrationBarcode
The invention discloses a system for visually identifying and analyzing as well as identifying drug allergy. The system comprises an optical and digital image acquiring device, a digital image processing device and a drug allergy identifying and analyzing device, wherein the optical and digital image acquiring device is used for providing a light source and acquiring the digital image, and sending the digital image to the digital image processing device; a polarizer and an analyzer in the optical and digital image acquiring device are used for strengthening the digital image of the detected object, and the cubic aberration of the digital image is corrected through a lens; the digital image processing device is used for receiving the digital image, capturing motion, performing filtration and feature enhancement on the image after sensing a target code, determining a target specimen type according to target specimen characteristics and bar code information after obtaining the target specimen image, selecting a detecting method to obtain detected results, processing and sending the detected results to the drug allergy identifying and analyzing device; the drug allergy identifying and analyzing device is used for identifying drug allergy by combining a mode identifying algorithm with preset CLIS (cost-of-living index) identifying standards in the drug allergy identifying and analyzing device, and obtaining the identifying conclusions.
Owner:北京浩辰星月科技有限公司 +1

Method for constructing ovarian cancer transplantation tumor model based on organoid method and application of method

The invention discloses a method for constructing an ovarian cancer transplantation tumor model based on an organoid method, and belongs to the field of medicines. According to the invention, an "organoid" culture technology is adopted, and a micro-carrier is used as a support material for culturing a patient-derived ovarian cancer cell-3D material complex; then the cell-3D material complex is directly inoculated under the skin of a normal immune mouse, and a patient-derived ovarian cancer transplantation tumor model is constructed, so that a problem that immune-deficiency mice such as severecombined immunodeficiency (SCID) mice, nude mice and the like are adopted in existing human ovarian cancer transplantation tumor models, the price is high, breeding is difficult, the tumor forming rate is low and the like can be solved, especially a problem that the existing immune-deficiency mouse human ovarian cancer transplantation tumor model cannot reflect impotent effects of an organism immune system in occurrence and development processes of tumors is solved, and a problem that an immune-deficiency mouse human transplantation tumor model is long in tumor forming period and cannot meet drug allergy requirements of patients urgently needing clinic drug therapy is solved. The method is applied to the field of mouse model construction.
Owner:上海美峰生物技术有限公司

Silver nanoparticles, preparation method thereof and nano silver dressing

The invention provides silver nanoparticles used for solving the problems that the existing hydrogel nano silver external patches or medical dressings have low adsorption capacities and the nano silver external patches or medical dressings have single function or complex components, thus easily causing user skin harms, heavy metal poisoning and drug allergy. The silver nanoparticles comprise the following components by weight percent: 90-98% of polysaccharide fibers, 0.5-6.5% of stabilizing agent and 0.03-3.5% of nano silver. The silver nanoparticles have the following beneficial effects: the silver nanoparticles are larger, have low moisture content, have higher absorbed amount of blood and fluid oozing from the wounds and can form a 2-3mm thick gel after absorbing the blood and fluid oozing from the wounds, thus not only preventing oozing fluid pollution and adhesion, isolating the external air and sources of infection and protecting the skins from friction or infection but also ensuring the silver nanoparticles to release slowly and ensuring the antibacterial and sterilization capabilities to be stronger and more lasting; and besides, the silver nanoparticles do not contain drug components, are nontoxic and harmless and can avoid user skin harms, heavy metal poisoning and drug allergy.
Owner:张利波

Method used for extracting antibacterial composition from limulus reagent production waste materials

The invention relates to a method used for extracting an antibacterial composition from limulus reagent production waste materials. The method comprises following steps: 1, raw material treatment is carried out, wherein a lower layer precipitate waste material obtained in centrifugation of an emulsified product in limulus reagent production is collected, and is taken as a raw material I, and discarded blood plasma in limulus reagent production is collected, and is taken as a raw material II; 2, extraction of a tachyplesin crude extracted solution is carried out, wherein acidolysis is carried out, pH is adjusted so as to remove a precipitate product, and thermal denaturation is carried out; 3, preparation of a hemocyanin crude extracted solution from blood plasma is carried out; 4, preparation of a SOD crude extracted solution is carried out; 5, 60 to 80 parts of the tachyplesin crude extracted solution,10 to 20 parts of the hemocyanin crude extracted solution, and 10 to 20 parts of the SOD crude extracted solution are mixed, pH value is adjusted to 4 to 5, and filtering is carried out so as to obtain the antibacterial composition. According to the method, the crude extracted solutions are prepared rapidly and conveniently at low cost; the antibacterial composition is capable of inhibiting growth of a plurality of kinds of bacteria and fungus; compared with conventional chemical antibacterial products, the antibacterial composition possesses following advantages: the antibacterial composition is safe, mild, and effective, no toxic or side effect is caused, and generation of drug resistance and drug allergy caused by conventional antibacterial products can be avoided.
Owner:GENOBIO PHARM CO LTD

Anti-wrinkle, freckle-removing and whitening itching relieving dew

The invention relates to anti-wrinkle, freckle-removing and whitening itching relieving dew. The itching relieving dew is prepared by eggplant juice, kunzea, bletilla striata, lucid ganoderma, aloe juice, feverfew, liquorice and traditional Chinese medicinal materials, has the efficacies of promoting blood circulation to remove blood stasis, beautifying skin and removing freckles, removing wrinkles, treating rhagadia manus and pedalis and diminishing inflammation and itching, has a strong medicine permeation effect and is free from rebound, and liquid medicine can be absorbed by skin within 3 minutes; the itching relieving dew can promote cell functions and blood circulation, enhance the activity of epidermic cells, promote metabolism and regulate endocrine and nervous functions and is fed three times a day, the color of spots is changed from deep to shallow after seven days, and the facial spots disappear within about 30 days, so that the skin is polished, is smooth and glows with good health; the problems that the conventional beautifying product only treats symptoms, not root causes, easily rebounds and reappears and the like are solved. The anti-wrinkle, freckle-removing and whitening itching relieving dew is mainly suitable for freckles, dark spots, pigmented spots, chloasma, butterfly rashes, acne, yellowish skin, darker skin, wrinkle removal, eye bag removal, drug allergy, pollen allergy, mosquito bite and the like.
Owner:王献美

Ceftazidime injectable powder for injection and preparation method of ceftazidime injectable powder for injection

The invention discloses ceftazidime injectable powder for injection and a preparation method of the ceftazidime injectable powder for injection. The ceftazidime injectable powder for injection comprises the following raw materials in parts by weight of 8.26-12.31 parts of ceftazidime, 6.45-9.22 parts of chitosan nanoparticles, 0.06-3.8 parts of arginine, 0.06-3.8 parts of lysine, 0.82-5.3 parts ofsuperfine bacteria-free sodium carbonate and 0.00005-0.0019 part of sodium bisulfite. The ceftazidime injectable powder for injection disclosed by the invention is high in purity, particularly low inimpurity content, good and stable in quality, better in clarity and wide in in vitro antibacterial activity spectrum, the antibacterial activity of the ceftazidime on Gram-negative bacteria can be significantly strengthened, the content of polymers is low, drug allergy reactions are reduced, the dissolving speed is high, the ceftazidime injectable powder for injection can quickly dissolve even atlow temperature of 10 DEG C, and the ceftazidime injectable powder for injection is convenient in clinical use. The preparation method of the ceftazidime injectable powder for injection disclosed bythe invention is simple and convenient to operate, low in cost, good in safety and suitable for industrial production.
Owner:上海欣峰制药有限公司

Clinical drug allergy management method, auxiliary device and system

InactiveCN113393945AStandardize the allergy management processGuarantee drug safetyDrug referencesDrug utilisationDrug allergy
The invention discloses a clinical drug allergy management method, auxiliary device and system. The method comprises the steps: receiving drug allergy information of a patient, and enabling the drug allergy information to comprise structured drug allergy information or unstructured drug allergy information according to different information sources; analyzing the unstructured drug allergy information to obtain structured drug allergy information; standardizing the non-standard name of the single medicine to obtain a standard name of the single medicine; and/or standardizing the non-standard names of the medicines to obtain the standard names of the specific single medicines under the classification of the medicines; and/or carrying out standardized extraction on similar and same-component associated drugs with standard names; forming a personalized standard drug allergy information structured list for the patient through analysis and standardization, so that the effective management is achieved in the diagnosis and treatment link of the patient, and the medication safety of the patient is effectively guaranteed. According to the invention, the completeness and availability of the drug allergy information record can be effectively improved.
Owner:FUWAI HOSPITAL CHINESE ACAD OF MEDICAL SCI & PEKING UNION MEDICAL COLLEGE

Method for differentiating ureaplasma urealyticum and ureaplasma parvum in ureaplasma with culture method

ActiveCN107746875AEasy to operateEasy for clinical promotion and useMicrobiological testing/measurementBiological material analysisUreaplasma parvumManganese
The invention discloses a method for differentiating ureaplasma urealyticum and ureaplasma parvum in ureaplasma with a culture method. The method comprises the following steps: determining two detection micropores which are respectively marked as a first hole and a second hole, wherein the first hole does not contain additive, a manganese and magnesium solution is added into the second hole, and magnesium and manganese ions are attached to the inner wall of the second hole after being dried; adding a sample to be tested into a ureaplasma culture medium, after even mixing, respectively adding into the first hole and the second hole, and culturing mixture for 24-48 hours at 37 DEG C; according to the color change situation of the first hole and the second hole, determining whether the ureaplasma urealyticum and the ureaplasma parvum are contained in a sample or not. The preparation of a kit through the method disclosed by the invention is more convenient and practical. The authenticationmethod is simple in operation, whether a sample contains the ureaplasma urealyticum and the ureaplasma parvum or not can be accurately differentiated through one step, meanwhile, the method can be combined with drug sensitivity detection, and meanwhile, an authentication and drug allergy result can be carried out. The detection kit prepared according to the method principle disclosed by the invention has the advantages of visual and accurate authentication result and is convenient for clinical popularization and use.
Owner:AUTOBIO DIAGNOSTICS CO LTD

Method for distinguishing ureaplasma urealyticum and ureaplasma parvum in ureaplasma by using culture method

ActiveCN107619849AEasy to operateEasy for clinical promotion and useMicrobiological testing/measurementBiotechnologyUrease enzyme
The invention discloses a method for distinguishing ureaplasma urealyticum and ureaplasma parvum in ureaplasma by using a culture method. The method comprises the following steps: firstly, confirmingtwo detection micro-pores, namely a pore A and a pore B; putting a proper amount of glucose or / and a urease inhibitor into the pore A, putting a manganese-magnesium solution into the pore B, drying, adhering the glucose or / and the urease inhibitor to the inner wall of the pore A, and adhering manganese ions and magnesium ions to the inner wall of the pore A; putting a sample to be tested into a ureaplasma culture medium, uniformly mixing, respectively putting into the pore A and the pore B, and culturing for 24-48 hours at 37 DEG C; and according to the color change situations of the pore A and the pore B, confirming whether the sample has ureaplasma urealyticum and ureaplasma parvum or not. A kit which is relatively convenient to use is prepared according to the method. The method disclosed by the invention is simple to operate, whether a specimen contains the ureaplasma urealyticum and the ureaplasma parvum or not can be precisely distinguished at one step, meanwhile, the method canbe implemented together with drug allergy detection, and identification and drug allergy results can be achieved; and identification results are visible and accurate, and clinical popularization and application are facilitated.
Owner:AUTOBIO DIAGNOSTICS CO LTD

Drug allergy detection device and method for cancer patients

InactiveCN111812310AAchieve the effect of allergy detectionWell mixedBiological testingDrug allergyPharmaceutical drug
The invention relates to the technical field of drug allergy detection and further discloses a drug allergy detection device for cancer patients. A base is included. A mounting plate is fixedly connected to the upper end of the base, a conical gear ring is fixedly connected to the left side of the mounting plate, a supporting plate is fixedly connected to the right side of the mounting plate, a motor is fixedly connected to the upper end of the supporting plate, a rotating shaft is fixedly connected to an output end of the motor, and a U-shaped rod is fixedly connected to the end, away from the motor, of the rotating shaft. According to the drug allergy detection device for cancer patients, the U-shaped rod drives a connecting column to synchronously rotate so as to drive a detection testtube to synchronously rotate; a bevel gear is matched to revolve around an axis of the bevel gear ring and autoroatation is generated at the same time; and a first transmission wheel is indirectly driven to synchronously rotate so that the detection test tube is driven to synchronously rotate through the connecting column, and the detection test tube rotates around the axis of the rotating shaft and the axis of the connecting column at the same time so that effects of more uniform medicament mixing and high result reliability are achieved.
Owner:刘燕
Who we serve
  • R&D Engineer
  • R&D Manager
  • IP Professional
Why Eureka
  • Industry Leading Data Capabilities
  • Powerful AI technology
  • Patent DNA Extraction
Social media
Try Eureka
PatSnap group products