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33 results about "Interventions therapy" patented technology

Biomedical magnesium or magnesium alloy implantation material with multiple surface protection

The invention discloses a magnesium or magnesium alloy material or device with multiple surface protection layers and a production method. The magnesium or magnesium alloy material or device with multiple surface protection treatment has the aims that the initial mechanical attenuation of magnesium / magnesium alloy in a physiological environment is decelerated, the corrosion resisting property of the magnesium / magnesium alloy is improved, and the time of service is effectively prolonged. The protection treatment comprises the steps: 1) manufacturing a magnesium / magnesium alloy substrate, and cleaning the surface of the substrate; 2) carrying out chemical conversion treatment on the surface of the magnesium / magnesium alloy substrate, so as to grow a chemical conversion film, of which the thickness is several nanometers, on the surface of the substrate; 3) coating the chemical conversion film with an adhesive layer; 4) coating the outside surface of the adhesive layer with a degradable polymer film. The magnesium or magnesium alloy material or device with multiple surface protection treatment, provided by the invention, can be applied to biomedical implantation or intervention therapy and has the advantages of being good in initial corrosion resisting property in a human physiological environment, meeting clinical requirements of medical treatment and being finally in-vivo degradable.
Owner:NANJING NORMAL UNIVERSITY

Detection kit for detecting relative expression level of PML-RAR (alpha) fusion gene by use of fluorescent quantitative PCR (polymerase chain reaction) technology

The invention relates to a detection kit for detecting the relative expression level of PML-RAR (alpha) fusion gene by use of fluorescent quantitative PCR (polymerase chain reaction) technology. The detection kit comprises the following materials in part ratio: red blood cell lysis buffer, TRIzol, chloroform, absolute ethyl alcohol, reverse transcription PCR reagent, detection system PCR reaction liquid, positive control substance and negative control substance. The kit provided by the invention has the advantages that the precision is high, the result is convenient to read, both the amplification efficiency and the rate reach the best level and the like; the complicated condition grope link is omitted; and the experimental efficiency is greatly improved. The kit has good specificity and high sensitivity and is easy and convenient to operate according to the test. The detection kit is favorable for the trace residue detection of the PML-PAR (alpha) (type L/type S) fusion gene in a clinical APL (acute promyelocytic leukemia) patient, and has great importance in performing timely intervention therapy to avoid hematological recurrence, adjusting the therapeutic schedule, evaluating the therapeutic effect, predicting the prognosis and preventing clinical recurrence.
Owner:FUZHOU ADICON CLINICAL LAB INC

Drug intervention therapy device for medical oncology

The invention discloses a drug intervention therapy device for medical oncology. The drug intervention therapy device comprises a supporting shelf, a puncture drainage device, a hemostasis device, a drug administration device, a control device and a power supply; the supporting shelf comprises bases, telescopic columns, a supporting beam and a slide sleeve; the puncture drainage device comprises apuncture needle and a drainage bottle; the drug administration device comprises a drug storage tank; the control device comprises a controller, a remote control unit and a processor; the telescopic columns are arranged on the bases; the supporting beam is arranged on the telescopic columns, the slide sleeve is arranged on the supporting beam, and a fixation box is arranged at the lower end of theslide sleeve; a puncture device is arranged at the lower end of the fixation box; drug storage devices are arranged on the bases; the controller is connected with the telescopic columns, the remote control unit and the processor are connected with the controller, and the power supply supplies power to the telescopic columns. By means of the drug intervention therapy device, the focus part can besubjected to drug administration and hydrop drainage, the hemostasis device is arranged, the clinic using effect is good, and the drug intervention therapy device is suitable for being popularized ona large scale.
Owner:AFFILIATED CANCER HOSPITAL OF SHANDONG FIRST MEDICAL UNIV SHANDONG CANCER INST (SHANDONG CANCER HOSPITAL)

Vascular intervention operation collection device and vascular intervention operation collection method

ActiveCN105769343AAutomated surgerySurgical robotsHand partsHand movements
The invention discloses a vascular intervention operation collection device based on an improved optical fiber data glove and a vascular intervention operation collection method based on an improved optical fiber data glove. The device comprises an operation guide wire circumferential rotary collection module, an operation guide wire axial propelling collection module, a support auxiliary module and a data processing module, wherein the operation guide wire circumferential rotary collection module is used for collecting finger bending curvature information when an operator rotates a guide wire; the operation guide wire axial propelling collection module is used for collecting hand movement information when the operator propels or withdraws the guide wire; the support auxiliary module is used for supporting a simulated blood vessel environment and enabling the front end of the guide wire to be positioned in an effective magnetic field emission region of an electromagnetic positioning system; the data processing module is used for processing, analyzing and converting the collected data. The vascular intervention operation collection device is capable of performing modeling analysis on hand and finger movement in an operation process; the method is capable of tracking movement of the guide wire in a vascular intervention therapy, so that the operator can effectively control the propelling and rotary motion of the guide wire, the operation precision is improved, and the recovery period of a patient is shortened.
Owner:北京中科鸿泰医疗科技有限公司

Method for screening active components from traditional Chinese medicine or natural medicine complex system and purposes thereof

The invention relates to a method for screening active components from a traditional Chinese medicine or natural medicine complex system, and provides the method for screening the active components from the traditional Chinese medicine or natural medicine complex system on the basis of metabonomics and traditional Chinese medicine chemical composition analysis technology. The method is characterized in that: establishing a related disease animal model, performing intervention therapy on effective parts by use of a traditional Chinese medicine or a natural medicine compound prescription or an element-plus/minus prescription of the traditional Chinese medicine or the natural medicine compound prescription; aiming at drug intervention-treated animal body fluids or tissues for metabonomics study to obtain curative effect differences information of medicine treatment groups; using a multivariate statistical analysis method to for search and identification of chemical constituents of differences so as to lead compounds or compound groups with active effects in the traditional Chinese medicine or natural medicine compound prescription. The method for screening the active components is reasonable and feasible. The method for screening the active components can be used as a method to develop new drugs from the traditional Chinese medicine or natural medicine complex system, also can be used as supplementary means for quality control of traditional Chinese medicines or natural medicine compound medicines.
Owner:INST OF MEDICINAL PLANT DEV CHINESE ACADEMY OF MEDICAL SCI

Liposomal corticosteroids for treatment of inflammatory disorders in humans

InactiveCN104144679AEfficient removalOvercome inherent problemsOrganic active ingredientsAntipyreticLipid formationCorticosteroid preparation
The invention relates to a pharmaceutical composition comprising liposomes composed of non-charged vesicle-forming lipids, optionally including not more than 10 mole percent of negatively charged vesicle- forming lipids and / or not more than 10 mole percent of PEGylated lipids, the liposomes having a selected mean particle diameter in the size range of 40-200 nm and comprising a first corticosteroid in water soluble form, for the site-specific treatment of inflammatory disorders in humans, providing in human patients a fast, strong, and durable anti-inflammatory effect for at least 2 weeks at a dose of at most 5 mg / kg body weight of prednisolone or an equipotent dose corticosteroid other than prednisolone at a treatment frequency of at most once per two weeks. Furthermore the present invention relates to the application of the above-mentioned pharmaceutical composition given as intervention therapy in inflammatory disorders such as rheumatic disease or a related inflammatory connective tissue disorder, inflammatory diseases of the kidney or inflammatory bowel disorders, in combination with chronic therapy with a second free corticosteroid formulation or in combination with chronic treatment with a disease- modifying agent such as methotrexate.
Owner:ENCELADUS PHARMA BV

Vascular lens-end balloon for arhythmia radiofrequency ablation

The invention provides a vascular lens-end balloon for vascular intervention therapy. The vascular lens-end balloon comprises a balloon body, a balloon top-end electrode, balloon surrounding electrodes, balloon electrode leads and a balloon vascular lens-end interface. The balloon body is of a dual-layer structure which comprises an inner layer and an outer layer; the balloon electrode leads are connected to the balloon top-end electrode and the balloon surrounding electrodes and the balloon electrode leads can move between the inner layer and the outer layer of the balloon body; the balloon vascular lens-end interface is connected into the balloon body; both ends of the balloon vascular lens-end interface are hollowed; a spiral structure is arranged in the balloon vascular lens-end interface; balloon electrode lead interfaces are arranged at the tail end of the interior of the balloon vascular lens-end interface; and the balloon electrode lead interfaces are connected to the balloon electrode leads. The vascular lens-end balloon provided by the invention has the beneficial effects that (1) a platform is provided for endoscopic cardiovascular examination in blood vessels and for arhythmia radiofrequency ablation therapy; the influence of blood on images is eliminated; and the vascular lens-end balloon, which is unnecessary to block a blood flow, is simple and convenient to operate; and (2) the arhythmia radiofrequency ablation therapy can be conducted under the direct vision of a vascular endoscopy, so that the use of rays is reduced; therefore, the vascular lens-end balloon is simple, convenient and safe.
Owner:黄冰生

Nursing assisting device for intervention therapy department

The invention discloses a nursing assisting device for the intervention therapy department. The device includes a body, the side walls of the left side and right side of the body are fixedly provided with locking belts, one end of each locking belt is fixedly provided with a clamping buckle, the other end of each locking belt is fixedly provided with a clamping head, the top of the body s fixedly provided with a pressurization device, the pressurization device includes a housing, the left side of the top of the housing is movably connected with one end of a pressing rod through a supporting frame and a rotating shaft, the other end of the pressing rod is fixedly provided with a handle, the center position of the pressing rod is fixedly provided with a connecting rod through the rotating shaft, the bottom of the connecting rod is fixedly connected with a piston, the piston is closely attached to the inner side of the housing, the body is further provided with an opening, a rubber sleeve is fixed to the open position of the opening, the inner wall of the opening is further provided with a sterilization device, a heating device is located on the left side of an inner cavity of the body, and the inner cavity of the body is further provided with a pressure sensor. The device is simple in structure and high in practicability.
Owner:NINGBO RONGHUI NANO TECH CO LTD

Novel titanium stent for aged coronary artery and treatment method of titanium stent

InactiveCN106729968ACoronary immunomodulationTissue regenerationCoatingsPhosphateThrombus
The invention discloses a novel titanium stent for aged coronary artery and a treatment method of the titanium stent. A stent body is made of a titanium material. The treatment method comprises the following steps of adsorbing a nanoparticle composition onto the surface of the stent body; after the surface of the stent body is polished and cleaned, soaking the stent body into an NaOH (sodium hydroxide) solution, reacting for 10h at the temperature of 70 DEG C, cleaning by ultrasonic waves in primary distilling water, soaking into secondary distilling water, reacting for 10h at the temperature of 70 DEG C, cleaning by ultrasonic waves in primary distilling water, and drying at the temperature of 37 DEG C; soaking the stent body into PLL (poly-l-lysine), standing for reacting for 20h at the temperature of 4 DEG C, and cleaning the stent body by a phosphate buffer solution. The GDP (guanosine diphosphate) at the surface of the stent body is combined with HEP (haperin), PLL, LN (laminin) or SDF-1apha (stromal derived factor-1alpha) to build a biological functional micro-environment with effects of coronary artery immune regulation, blood compatibility, coronary artery thrombus formation inhibition, coronary artery endothelial injury recovery, and coronary interventional treatment restenosis inhibition, so as to possibly solve the problems of coronary artery thrombus formation and restenosis caused by intervention therapy for coronary multi-vessel lesions and complex coronary artery lesion.
Owner:淮安市第二人民医院(淮安仁慈医院)

A method for screening active ingredients from complex systems of traditional Chinese medicine or natural medicine and its application

The invention relates to a method for screening active components from a traditional Chinese medicine or natural medicine complex system, and provides the method for screening the active components from the traditional Chinese medicine or natural medicine complex system on the basis of metabonomics and traditional Chinese medicine chemical composition analysis technology. The method is characterized in that: establishing a related disease animal model, performing intervention therapy on effective parts by use of a traditional Chinese medicine or a natural medicine compound prescription or an element-plus / minus prescription of the traditional Chinese medicine or the natural medicine compound prescription; aiming at drug intervention-treated animal body fluids or tissues for metabonomics study to obtain curative effect differences information of medicine treatment groups; using a multivariate statistical analysis method to for search and identification of chemical constituents of differences so as to lead compounds or compound groups with active effects in the traditional Chinese medicine or natural medicine compound prescription. The method for screening the active components is reasonable and feasible. The method for screening the active components can be used as a method to develop new drugs from the traditional Chinese medicine or natural medicine complex system, also can be used as supplementary means for quality control of traditional Chinese medicines or natural medicine compound medicines.
Owner:INST OF MEDICINAL PLANT DEV CHINESE ACADEMY OF MEDICAL SCI

Cardiovascular intervention therapy device

The invention belongs to the field of medical instruments, and discloses a cardiovascular intervention therapy device which comprises a needle tube. A one-way valve is embedded into the front end of the needle tube, a rubber positioning piece is vertically mounted on the one-way valve, a push rod is movably mounted inside the needle tube, a hole plug is arranged inside the push rod, a rubber plugis fixedly mounted at the front end of the push rod and clamped inside the needle tube, a through hole is formed in the front end of the rubber plug, an elastic sealing diaphragm is mounted inside thethrough hole, a guide wire hole is formed in the rear end of the push rod and communicated with the hole plug, a push plate is integrally mounted at the rear end of the push rod, and a conical blockis arranged in the middle of the push plate. The one-way valve is arranged at a needle head of the cardiovascular intervention therapy device, when the needle head is inserted into a blood vessel, a clamping valve flap further clamps a guide wire under reverse thrust of blood pressure, reverse flow of blood is decreased, annular valve flaps are arranged in a needle cylinder and a piston, reverse flow of the blood is reduced to the minimum, surgical safety is greatly improved, pollution to a worktable top is avoided, and bacterial pollution is reduced.
Owner:HENAN YUQIAN TECH TRANSFER CENT CO LTD

Postcerebral intervention therapy postoperative fixator

InactiveCN110448419AEffective circumferential fixationEffectively fixedRestraining devicesNursing bedsInterventions therapyEngineering
The invention relates to the technical field of medical apparatuses, in particular to a postcerebral intervention therapy postoperative fixator. The postcerebral intervention therapy postoperative fixator comprises two joint fixing sleeves and two leg fixing sleeves, wherein the joint fixing sleeves and the leg fixing sleeves are connected through a connecting band I; the two joint fixing sleevesare sewed and fixed together through a connecting band II; the two leg fixing sleeves are sewed and fixed together through a connecting band III; a locking band I is connected to the side surface of each joint fixing sleeve in a sleeving manner; a bed body fixing seat is fixedly connected to the ends of the locking bands I; a locking band II is connected to the side surface of each leg fixing sleeve in the sleeving manner; and bed leg fixing sleeves are fixedly sewed to the side surface of the locking bands II. According to the postcerebral intervention therapy postoperative fixator disclosedby the invention, the joint fixing sleeves and the leg fixing sleeves are flexibly fixed, and are used for separately pulling and fixing the legs and the joints to the periphery, so that the limbs cannot be pressed; and the joints and the shanks of a patient are respectively subjected to effective protective fixation..
Owner:PEOPLES HOSPITAL OF HENAN PROV

Cardiovascular anesthesia interventional therapy device

The invention relates to a cardiovascular anesthesia type interventional therapy device and belongs to the technical field of medical instruments. The cardiovascular anesthesia type interventional therapy device comprises a power supply base, an interventional instrument combined case, an anesthesia case and a hemostatic oppression top box, wherein a hidden battery box is arranged in the power supply base; a winding roller rotating shaft is arranged in the interventional instrument combined case and connected with the interventional instrument combined case through rotating shaft nesting rings; a guide pipe winding roller is arranged on the winding roller rotating shaft; a guide pipe connecting mouth is arranged in the anesthesia case; a hard drainage channel is arranged on the guide pipe connecting mouth; an anaesthetic caching box is arranged on the lower side of the hard drainage channel; a top box protective cover is arranged on the hemostatic oppression top box; and a pressure pump switch is arranged on the upper side of the hemostatic oppression top box and connected with the hemostatic oppression top box through a switch chute. The cardiovascular anesthesia type interventional therapy device is complete in function and convenient to use, and can be simply and conveniently operated with less time and effort when used for cardiovascular interventional therapy on patients, thereby reducing the work difficulty of medical staff.
Owner:陈曦
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