The invention discloses a novel
titanium stent for aged coronary
artery and a treatment method of the
titanium stent. A
stent body is made of a
titanium material. The treatment method comprises the following steps of adsorbing a
nanoparticle composition onto the surface of the stent body; after the surface of the stent body is polished and cleaned, soaking the stent body into an NaOH (
sodium hydroxide) solution, reacting for 10h at the temperature of 70 DEG C, cleaning by ultrasonic
waves in primary distilling water, soaking into secondary distilling water, reacting for 10h at the temperature of 70 DEG C, cleaning by ultrasonic
waves in primary distilling water, and
drying at the temperature of 37 DEG C; soaking the stent body into PLL (poly-l-
lysine), standing for reacting for 20h at the temperature of 4 DEG C, and cleaning the stent body by a
phosphate buffer solution. The GDP (
guanosine diphosphate) at the surface of the stent body is combined with HEP (haperin), PLL, LN (
laminin) or SDF-1apha (stromal derived factor-1alpha) to build a biological functional micro-environment with effects of coronary
artery immune regulation,
blood compatibility, coronary
artery thrombus formation inhibition, coronary artery endothelial injury
recovery, and coronary
interventional treatment restenosis inhibition, so as to possibly solve the problems of coronary artery
thrombus formation and
restenosis caused by intervention therapy for coronary multi-vessel lesions and complex coronary artery
lesion.