The utility model discloses a novel prefabricated high-strength combined guardrail structure for a bridge. A prefabricated concrete base unit is used for being connected with a bridge panel and fixing a steel structure guardrail unit; a wet joint notch is formed in the bottom face of one side of a head-on collision face of each prefabricated concrete base unit, annular steel bars are arranged in the wet joint notches, U-shaped steel bars are arranged on a bridge face plate, and the adjacent annular steel bars are connected through longitudinal steel bars in a binding mode. The annular reinforcing steel bars and the U-shaped reinforcing steel bars are oppositely staggered, U-shaped openings of the U-shaped reinforcing steel bars are provided with hooks, transverse sealing reinforcing steel bars are arranged between the hooks of the U-shaped reinforcing steel bars, and the transverse sealing reinforcing steel bars and the longitudinal reinforcing steel bars are arranged in an intersecting mode. According to the scheme, on one hand, the prefabricated concrete base unit is connected with the bridge panel through the
cement mortar cushion layer, on the other hand, the open-type wet joint notches are formed, connection between the prefabricated concrete base unit and the bridge panel is enhanced through the UHPC grouted in the notches and the steel bars arranged in the staggered mode, the construction quality is effectively guaranteed, and the construction difficulty is reduced; and the quality of the prefabricated guardrail is effectively improved.