1results about How to "Improve dissolution behavior" patented technology

The invention discloses a tigorazan amorphous solid dispersion, a tigorazan-containing tablet core, a tigorazan tablet and a preparation process of the tigorazan amorphous solid dispersion. The invention specifically discloses a tigorasan solid dispersion. The tigorasan solid dispersion comprises tigorasan and a carrier, the tigorasan is one or more of a tigorasan A crystal form, a tigorasan B crystal form and a tigorasan amorphous form; the carrier comprises copovidone and polyethylene glycol; the mass ratio of the copovidone to the polyethylene glycol is 1: (0.5-2). The invention also provides a preparation method of the tigorazan solid dispersion, a tigorazan-containing tablet core and a preparation method thereof, and a tigorazan tablet and a preparation method thereof. According to the method disclosed by the invention, wet granulation is adopted, so that the preparation process is simpler, the product quality is easier to control, the production efficiency is improved, large-scale production is facilitated, and the prepared tigoraz tablets are good in content uniformity and good in stability.