The invention discloses an antibacterial sound insulation board, which is made from the following ingredients in parts by weight: 5-10 parts of nanometer titanium dioxide, 5-6 parts of nano silver particle, 40-80 parts of high damping silicone rubber, 40-50 parts of EPDM rubber, 15-30 parts of basalt fiber, 1-2 parts of benzoyl peroxide, 80-100 parts of EVA resin, 20-30 parts of white carbon black, 4-6 parts of hydroxyl silicone oil, 23-38 parts of foam ceramic powder, 2-4 parts of mica powder, 0.3-0.5 part of zinc oxide, 2-4 parts of stearic acid, 1.2-1.8 parts of accelerator, 2-3 parts of antioxidant, 5-9 parts of bamboo charcoal particles, 3-7 parts of zinc borate, 5-8 parts of high vinyl silicone oil and 0.2-0.4 part of silane coupling agent. The antibacterial sound insulation board prepared by the invention has the antibacterial rate over 99%, the sound absorption coefficient over 0.8, the compressive strength >= 8 MPa, the breaking strength>= 25 MPa, and excellent flame retardancy.