38 results about "Metal poisoning" patented technology

Methods and pharmaceutical compositions for providing neuroprotection to the animal central nervous system against the effects of ischemia, and neurodegeneration. Patients at risk for certain diseases or disorders that are associated with cerebral ischemia may benefit, e.g., those at risk for Alzheimer's disease, Parkinson's disease, Wilson's disease or stroke or those patients having head or spinal cord injury. Patients undergoing certain medical procedures that may result in ischemia may also benefit. Initially, the possibility of ischemia or neurodegeneration is recognized. Intranasal therapeutic agents are administered to the upper third of the nasal cavity to bypass the blood-brain barrier and access the central nervous system directly to avoid unwanted and potentially lethal side effects. Therapeutic agents include those substances that interact with iron and / or copper such as iron chelators and copper chelators. A particular example of such therapeutic agents is the iron chelator deferoxamine (DFO). Intranasal administration of DFO provides an effective method for pre-conditioning the brain to protect against cerebral ischemia.

Methods and pharmaceutical compositions for preconditioning and / or providing neuroprotection to the animal central nervous system against the effects of neurological disorders involving ischemia, trauma, metal poisoning and neurodegeneration, including the associated cognitive, behavioral and physical impairments. In one embodiment, the method is accomplished by stimulating and / or stabilizing hypoxia-inducible factor-1α (HIF-1α). HIF-1α is known to provide a neuroprotective benefit under ischemic conditions. In another embodiment, the method is accomplished by differentially reducing, inhibiting or preventing the increased expression of selected genes caused by neurological disorders. Patients at risk for certain diseases or disorders that are associated with risk for cerebral ischemia may benefit, e.g., those at risk for Alzheimer's disease, Parkinson's disease, Wilson's disease, Huntington's disease, thalassemia or stroke, or those patients having head or spinal cord injury. Patients undergoing certain medical procedures that may result in ischemia may also benefit. Initially, the possibility of ischemia or neurodegeneration is recognized. Intranasal therapeutic agents are administered to the upper third of the nasal cavity to bypass the blood-brain barrier and access the central nervous system directly to avoid unwanted and potentially lethal side effects. Therapeutic agents include those substances that interact with iron and / or copper such as iron chelators, copper chelators, and antioxidants. Particular examples of such therapeutic agents are the iron chelators deferoxamine (DFO) and deferasirox. Intranasal administration of DFO is known to stimulate and / or stabilize HIF-1α and provides an efficient and safe method for pre-conditioning the brain to protect against cerebral ischemia.

The invention discloses a novel cerium oxide denitration catalyst. The novel cerium oxide denitration catalyst has the expression formula of CeNaOx, wherein the molar ratio of Ce to Na is (90-98):(10-2), and x is balanced and determined by positive and negative valence electrons in each atom. The preparation method of the catalyst comprises the following steps of: 1, dissolving cerous sulfate, sodium phosphate and cerium sulfate in water at normal temperature, and stirring to form a transparent solution; 2, transferring the prepared solution into a hydrothermal reaction kettle, and adding deionized water; 3, sealing the hydrothermal reaction kettle and transferring the hydrothermal reaction kettle to an oven for heating and reacting, reducing the temperature, performing centrifugal separation, and cleaning until no sulfate radical is detected by using deionized water; and 4, drying and roasting the centrifuged precipitate, thereby obtaining the catalyst. The metallic oxide catalyst is in the range of 200-500 DEG C, and the purification efficiency of nitric oxide is 71-100 percent; and the composite oxide catalyst has high high-altitude-resistant speed and good alkali-resistant metal poisoning performance, the efficiency is greatly improved, and the operating cost can be obviously reduced.

The present invention is directed to methods for treating or ameliorating skin conditions, diabetic conditions, cardiovascular conditions, cancer, infections or metal poisoning, enhancing performance, or providing nutritional support, comprising administering to a subject in need thereof compositions comprising a magnetic dipole stabilized solution (MDSS). The MDSS solution may include additional components and can be provided in a kit.

The invention discloses a bamboo shoot superfine powder adsorbent and a preparation method thereof. The bamboo shoot superfine powder adsorbent of the present invention is prepared with bamboo shoots as raw material, comprising the following steps: (1) selecting and cleaning the raw material; (2) cutting into pieces; (3) drying; (4) coarsely pulverizing and sieving; (5) ) enzyme activation treatment; (6) drying; (7) ultrafine grinding and sieving. The present invention degrades cellulose and hemicellulose in bamboo shoots through enzyme activation treatment to convert them into soluble small-molecule dietary fibers, and the overall structure becomes bulky and porous, and is processed by ultrafine pulverization technology to increase the size of bamboo shoot diet The specific surface area of ​​the fiber enhances the adsorption capacity. Adding it to food can help absorb heavy metals left in the human body and prevent metal poisoning.

The invention discloses a SCR denitration catalyst. The SCR denitration catalyst comprises a base material and auxiliaries doped in the base material, wherein the base material comprises power purified from dust generated in a glass furnace, and further comprises titanium dioxide doped in the powder. The invention further discloses a synthesis method for a catalytic material, and the synthesis method comprises the following steps: (1) cleaning dust generated by the glass furnace to remove impurities which can be dissolved into water; (2) stirring and dissolving the dust into diluted nitric acid or diluted hydrochloric acid, meanwhile, adding titanium dioxide to at least remove potassium oxide and sodium oxide in dust; (3) extracting un-dissolved precipitates; and (4) drying, roasting and crushing to obtain raw material powder. The SCR denitration catalyst can solve treatment of dust generated by the glass plant furnace, recycles resources, and expands the raw material supply channel ofthe SCR denitration catalyst manufacturing enterprises. The prepared SCR denitration catalyst is improved in the aspects of sulfur resistance, alkaline metal poisoning resistance and wear resistance.

The invention relates to two novel amino substituted carboxylic acid compounds and a preparation method thereof. The compounds can be used for the prevention and treatment of in-vivo metal poisoning and the preparation of metal decorporation medicaments and health products. The amino substituted carboxylic acid compounds combine the advantages of aminocarboxylic acid and phenolic hydroxyl; and the two novel chelators designed by effectively introducing carboxyl chelation groups onto the benzylic site of a benzene ring have fine metal poisoning prevention and treatment activity and metal decorporation activity. By adding the effective chelation groups on the benzylic site in the molecule chelation center, the nuclide ion bonding capability is enhanced, so that the compounds can be easily formed into stable complexes, thereby accelerating the in-vivo discharge and improving the decorporation effect and poisoning prevention and treatment effect of metal (especially uranium).

An acid soil curing agent and a preparing method thereof are provided. The curing agent comprises or is composed of silica, potassium bicarbonate and water. The curing agent corrects overly acidic conditions of soil, improves toxicity of metals of divalent or more such as aluminum and manganese, and supplements active elements essential for crop growth. The curing agent functions from a plurality of aspects, improves soil acidity and cures the acid soil.