The invention belongs to the technical field of
new materials, and particularly relates to temperature-pH dual-response
antioxidant hollow
mesoporous silica nanoparticles as well as a preparation method and application thereof. The method disclosed by the invention comprises the following steps: S1, carrying out hydrophobic modification on HMSNs by adopting octadecyl trimethoxy
silane, so as to obtain HMSNs-C18; s2, carrying out
amination modification on the HMSNs-C18, so as to obtain HMSNs-C18-NH, and carrying out initiator fixation treatment on the HMSNs-C18-NH, so as to obtain HMSNs-C18-Br; the preparation method comprises the following steps: carrying out PNIPAM
grafting treatment on HMSNs-C18-Br to obtain HMSNs-C18-PNIPAM-Br, carrying out PAA
grafting treatment on the HMSNs-C18-PNIPAM-Br to obtain HMSNs-C18-PNIPAM-b-PAA, and carrying out PNIPAM
grafting treatment on the HMSNs-C18-PNIPAM-b-PAA to obtain HMSNs-C18-PNIPAM-b-PAA; and S3, grafting
gallic acid on the HMSNs-C18-PNIPAM-b-PAA, so as to obtain the temperature-pH (Potential of
Hydrogen) dual-response
antioxidant hollow mesoporous
silicon dioxide nano particles. By adopting the temperature-pH dual-response
antioxidant hollow
mesoporous silica nanoparticle entrapped
plant essential oil prepared by the invention, the
solubility and
bioavailability of the
essential oil can be improved, the active ingredients of the
essential oil are protected, the release of the active ingredients is controlled, and the storage stability, bacteriostasis and
oxidation resistance of the essential oil are improved. The effects of
oxidation resistance, bacteriostasis and the like of the essential
oil can also be remarkably improved through the slow release effect.