The invention discloses a medicine composition capable of reducing blood fat, reducing blood viscosity and softening blood vessels. The medicine composition is prepared from fructus phyllanthi, fructus lycii, dried full grass of veronica eriogyne, Chinese angelica, kudzuvine root, herba dracocephali tangutici, coriander, dried lagotis brevituba maxim, faeces ochotonae erythrotis, ligusticum wallichii, herba meconopsis, astragalus membranaceus, pterocephali herba, safflower carthamus, lignum dalbergiae odoriferae, Tibetan radix rubiae, radix aucklandiae, fructus aristolochiae, tea tree root, lacca, dendrobe, Tibetan radix lithospermi, dried full grass of saxifraga umbellulata, fructus chebulae, hawthorn leaf, fructus terminaliae billericae, radix polygonati officinalis, gastrodia elata, herpetospermum pedunculosum, radix aucklandiae, hairy antenoron herb, tinospora sinensis merr, Tibet inula root, hippophae rhamnoides fruit paste, calculus bovis, radix et rhizoma rhodiolae kirilowii seu bergeniae, and mulberry leaves and the like; the medicine composition is prepared from traditional Chinese medicines and Tibetan medicines, has the effects of cooling blood, reducing blood pressure, promoting blood circulation to remove blood stasis, clearing and activating the channels and collaterals, dispelling wind, relieving pain and the like, has good effects of promoting blood circulation, reducing blood viscosity and softening blood vessels after being taken or eaten for a long time, and has good treatment and prevention effects on hyperlipidemia; and the medicine effect is mild and the side effect is low.