The invention discloses a preparation method of a multi-layer microcapsule for delivering
fucoxanthin, and belongs to the technical field of food and
drug processing. The preparation method comprises the following steps: S1, mixing
krill oil with a co-emulsifier to obtain a
microemulsion, adding
fucoxanthin, stirring to obtain a
krill oil self-
microemulsion system, adding water, and mixing to obtain a
fucoxanthin-loaded
microemulsion; s2, mixing the obtained fucoxanthin-loaded microemulsion with
chitosan, and adding a
polysaccharide solution into the obtained
mixed solution for mixing, so as to obtain a feed solution; and S3,
drying the feed liquid to obtain the fucoxanthin-loaded microcapsule. The microcapsule
wall material is prepared through electrostatic layer-by-layer deposition on the fucoxanthin-loaded microemulsion, and then
spray drying is performed to obtain the fucoxanthin-loaded multilayer microcapsule, so that the
bioavailability of fucoxanthin can be improved, and fixed-point release of fucoxanthin is realized.